Sentences with phrase «attach ubiquitin»

The gene BRCA1 makes a protein that can attach ubiquitin, which helps to regulate processes in the body, to other proteins.

Elimination of a single amino acid — a proline — in this region abrogates VHL's ability to attach ubiquitins and thus safeguards HIF - 1.

Not exact matches

In this study, the researchers found that macrophages from mice lacking Smurf1 were unable to attach the death - tagging protein ubiquitin to intracellular bacteria, resulting in a failure of the autophagy pathway and runaway growth of the bacteria inside the cells.

SUMOylation occurs when an enzyme attaches a molecular tag called a Small Ubiquitin - like Modifier (SUMO) to a protein, altering its activity and location in the cell.

When both halves of Kusabira Green are next to each other, green light is emitted — so the net result is that a cell will light up wherever the two ubiquitin molecules are attached to one another.

Ubiquitin is a tiny protein that attaches itself to other proteins in the cell, like the misfolding misfits noted above, and targets them to be degraded.

In all ubiquitination previously observed, the cascade of three E enzymes performed a sort of relay in which one activated a ubiquitin protein, one transferred it to the target protein and one attached it, he said.

His friend Michael Urban, another postdoctoral fellow, knew that a small protein called ubiquitin attached to a DNA - associated protein in the same unusual way that APF - 1 bound to proteins destined for destruction.