Sentences with phrase «attack against those tumor»

Engineered with special tumor - recognition molecules, Listeria prods the immune system into action, marshaling an attack against tumors that the body might otherwise be unable to combat.

Orchestrating a successful immune attack against tumors has proven difficult so far, but a new study from MIT suggests that such therapies could be improved by simultaneously activating both arms of the immune system.

Kwak has developed anti-cancer therapeutic vaccines to spark an immune system attack against tumors, but their effectiveness has been hindered by factors such as MDSCs that stifle immune response.

Immunity is key to long - term responses Knowing that the immune system is capable of recognizing distinctive features of cancer cells and launching a T cell attack against those tumor antigens, and that checkpoint blockade removes a roadblock to that attack, it's logical that these drugs should work against many tumor types.

Moderna initiated a Phase 1 study of mRNA - 2416, an intratumoral (iTu) immuno - oncology (I - O) therapeutic that encodes for the membrane expression of the co-stimulatory protein OX40 Ligand, or OX40L, to potentially enhance T - cell attack against tumors.

Not exact matches

On its own, this immune response had no immediate effect in the fight against the utilized breast tumors, but in combination with the ADC it proved itself effective in attacking cancer cells in mice, resulting in the complete cure of the majority of mice receiving the combination therapy.

One promising strategy in the fight against cancer is to use the body's own immune system to remove tumor cells, but due to a phenomenon called immune tolerance, the immune system has a difficult time identifying which cells to attack.

The intervention, he says, essentially trains the immune system to recognize and attack the tumor, and to protect against additional tumor formation — a significant issue in colon cancer.

Research is also underway to understand whether it can elicit a response against tumors that typically don't provoke an immune attack.

New research out of the University of Michigan supports combining two approaches to fight back against gliomas: attacking the tumor with gene therapy while enhancing the immune system's ability to fight it, too.

Instead of protecting the tumor, the TAMs now signaled the presence of the tumor to the immune system, triggering attacks against it — and did so very efficiently.

Cancer vaccines are designed to stimulate an immune response against tumor - specific or tumor - associated antigens, encouraging the immune system to attack cancer cells bearing these antigens.

Our researchers have identified a bacterial - based therapy for attacking pancreatic tumors, offering hope in the fight against one of the deadliest cancers.

In different contexts, viruses appear capable of attacking tumors in a number of different ways — by directly infecting them, by releasing tumor proteins that trigger a broad immune response against the cancer, and by damaging the blood supply tumors need to survive.

Therapeutic vaccines are designed to elicit an immune response against tumor - specific or tumor - associated antigens, encouraging the immune system to attack cancer cells bearing these antigens.

Therapeutic cancer vaccines are designed to elicit an immune response against tumor - specific or tumor - associated antigens, encouraging the immune system to attack cancer cells bearing these antigens.

They can attack cancer cells directly, or they can be used to trigger an immune response against the tumor (so - called cancer immunotherapy).

A novel approach to cancer immunotherapy — strategies designed to induce the immune system to attack cancer cells — may provide a new and cost - effective weapon against some of the most deadly tumors, including ovarian cancer and mesothelioma.

The chronically stressed mice had decreased immune function and experienced tumor development significantly earlier than the non-stressed mice.16 Other mouse studies of ovarian cancer showed that chronic stress resulted in increased cancer growth as well as increased angiogenesis, the process with which cancer forms new blood vessels to feed itself nutrients for growth and metastases.17 Chronic stress has also been shown to decrease our body's ability to mount an attack against foreign invaders, including viruses.18 As we know that several viruses can cause cancer (HPV and cervical cancer, and EBV and nasopharyngeal cancer), we can extrapolate that any decrease in immune function could increase cancer risk.

Immunotherapy is the ability of the immune system to protect against tumor development by attacking malignant cells once they arise.