Not exact matches
Whether the armamentarium of alternative
vaccine candidates presently in the pipeline (including inactivated, live
attenuated, chimeric, recombinant, subunit and DNA
vaccines) will improve efficacy beyond 56 % remains to be established.
The
candidate vaccine is made from a mixture of four live, weakened (
attenuated) viruses targeted to each of the four serotypes.
Volunteers received either one or two doses of the
candidate live
attenuated vaccine and then 12 weeks later received an inactivated H7N9
vaccine, manufactured by Sanofi Pasteur (Swiftwater, Pennsylvania).
MedImmune, a Maryland company, created the live
attenuated candidate H7N9
vaccine as part of a cooperative research and development agreement with NIAID.
MHRP scientists, working with NIAID, have developed an
attenuated viral vector — modified vaccinia Ankara —
vaccine candidate, MVA - CMDR (HIV - 1 CM235 env / CM240 gag - pol).
Moreover, a single intranasal immunization dose showed higher immunogenicity and protection than that conferred with a commercial inactivated
vaccine, making our live -
attenuated CIV an excellent
vaccine candidate for the prevention and control of CIV in dogs.
He has also generated
attenuated viruses as
vaccine candidates, for the treatment of influenza and arenavirus infections in humans and other mammalians.