Sentences with phrase «atypical development as»

These are topics that help educators understand «the course of typical and atypical development as well as age appropriate expectations for learning and behavior,» according to the report.

Not exact matches

The historic ferment and developments in modern Catholic thought are dismissed (if anything is known about them) as atypical or even hypocritical.

Can this atypical system of stellar rotation observed in MACS2129 - 1 be interpreted as a form of «prototype» representing an early stage in the development of elliptic - shaped galaxies?

This novel finding is important for our understanding of this complex condition and its development, and warrants further research on the possibility to use the atypical neural response to the own name as a potential biological marker of ASD.

In 2005, the identification of an activating mutation in JAK2 (the V617F mutation) as a STAT5 - activating and disease - causing genetic alteration in a significant proportion of patients with myeloproliferative neoplasms (MPNs) has emphasized the oncogenic role of the JAK tyrosine kinases in hematologic malignancies.2 — 5 JAK2 is a member of the Janus tyrosine kinase family comprising three other mammalian non-receptor tyrosine kinases (JAK1, JAK3 and TYK2) that associate with cytokine receptors lacking intrinsic kinase activity to mediate cytokine - induced signal transduction and activation of STAT transcription factors.6 All JAKs share a similar protein structure and contain a tyrosine kinase domain at the C - terminus flanked by a catalytically inactive pseudokinase domain with kinase - regulatory activity, by an atypical SH2 domain and by a FERM domain that mediates association to the membrane - proximal region of the cytokine receptors.7, 8 Soon after the discovery of JAK2 V617F, we and others described that activating JAK1 mutations are relatively common in adult patients with T - cell acute lymphoblastic leukemia (ALL) and participate in ALL development allowing for constitutive activation of STAT5.9 — 11 Several STAT5 - activating JAK1 mutations were also reported in AML and breast cancer patients.10

Join a free webinar with Dr. Elaine Schulte to learn how to differentiate between typical and atypical development and behavior in children, specifically as it relates to adopted children.

Summarizing the empirical evidence, Barnett and colleagues [75] suggested a two - dimensional model in which both biological vulnerability as well as adverse environment might contribute to the development of atypical (disorganised) attachment behaviour.

• to describe the lives of children in Ireland, in order to establish what is typical and normal as well as what is atypical and problematic; • to chart the development of children over time, in order to examine the progress and wellbeing of children at critical periods from birth to adulthood; • to identify the key factors that, independently of others, most help or hinder children's development; • to establish the effects of early childhood experiences on later life; • to map dimensions of variation in children's lives; • to identify the persistent adverse effects that lead to social disadvantage and exclusion, educational difficulties, ill health and deprivation; • to obtain children's views and opinions on their lives; • to provide a bank of data on the whole child; and to provide evidence for the creation of effective and responsive policies and services for children and families; • to provide evidence for the creation of effective and responsive policies and services for children and families.