Not exact matches
Dr David Aanensen, head of the Centre for
Genomic Pathogen Surveillance and joint lead
author on the
paper said: «Drug resistance is a growing problem both in Europe and across the world and doctors need fast and accurate information to stop epidemics.
«Our
paper reports that two highly conserved pathways — the UPR and the nonsense - mediated RNA decay pathway — intersect with each other at a pivotal point in cell stress,» said Miles Wilkinson, PhD, senior
author and professor in the Department of Reproductive Medicine and a member of the UC San Diego Institute for
Genomic Medicine.
The
authors of the
paper also found significant changes in the
genomic structure and gene families, contradicting the idea of a genuine «living fossil.»
Holly Ernest, a UW professor of wildlife
genomics and disease ecology, and Wyoming Excellence Chair in Disease Ecology, was senior
author of the
paper.
«These tools fill important and unmet needs in
genomics,» said Dr. Zhang, the senior
author of the two
papers.
This is our dream for personalized cancer therapy, so we're not just guessing any more about which drugs will work but can choose drug targets based on what's driving that patient's cancer,» said Josh Stuart, the Baskin professor of biomolecular engineering at UC Santa Cruz, director of cancer and stem cell
genomics at the UCSC
Genomics Institute, and a senior corresponding
author of the
paper.
The
authors of the
papers — Daniel L. Kaplan, associate professor at Florida State University who heads a
genomics lab, and Irina Bruck, assistant scholar scientist in Kaplan's lab — also received a correction in JBC this month, which cites image duplication.
«It's not so long ago it was very hard work to do a
genomic study in any organism,» said Leif Andersson of Uppsala University, an
author of the second published
paper.
Jennifer R. Grandis, a professor of otolaryngology and pharmacology and chemical biology at the University of Pittsburgh School of Medicine and a senior
author of one of the Science
papers, bemoaned the dearth of genetic information about head and neck cancer several years ago at a conference where Garraway had given a talk about the
genomic landscape of melanoma.
«This is an important new chapter in our ongoing work to understand the mechanisms driving
genomic diversity and through that the evolution of our species,» said Kari Stefansson, CEO of deCODE and senior
author on the
paper.
Authors on the
paper are: Atsushi Nakabachi of the UA and RIKEN; Helen E. Dunbar and Nancy A. Moran of the UA; Atsushi Yamashita and Hidehiro Toh of Kitasato University in Sagamihara, Japan; Hajime Ishikawa of The University of the Air in Mihama, Japan; and Masahira Hattori of The University of Tokyo in Kashiwa, Japan and RIKEN
Genomic Sciences Center in Yokohama, Japan.