Sentences with phrase «autocrine factors»
These factors, along with stem cell autocrine factors such as nodal and GDF - 3, might maintain a high local ratio of SMAD2 / 3 to SMAD1 signaling to drive stem cell maintenance.
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Immature human oocytes were matured in vitro via supplementation with ovarian paracrine / autocrine factors that were selected based on expression of ligands in the cumulus cells and their corresponding receptors in oocytes.
Further, ERK1 / 2 is known to get activated by autocrine factors without mutations in Ras [31].
Not exact matches
«Exercise - induced irisin may not only act as an endocrine factor capable of promoting the browning of white adipose tissue, but could also regulate bone metabolism by autocrine mechanisms,» said Chen, who also serves as faculty in the Cell, Molecular & Developmental Biology program at the Sackler School of Graduate Biomedical Sciences at Tufts.
Glucose regulated protein 94 is required for muscle differentiation through its control of the autocrine production of insulin - like growth factors.
Autocrine fibroblast growth factor 2 increases the multipotentiality of human adipose - derived mesenchymal stem cells.
These muscle - secreted factors have autocrine, paracrine and endocrine effects, explaining how muscles regulate metabolic homeostasis in other tissues.
Angiopoietin - 2 functions as an autocrine protective factor in stressed endothelial cells.
Autocrine motility factor / phosphoglucose isomerase regulates ER stress and cell death through control of ER calcium release.
[17 - 28] Much evidence indicates that GHRH acts as an autocrine / paracrine growth factor in many human cancers [6, 23, 29 - 31] including that of the breast.
Recently, some other cytokines (such as tumor necrosis factor) or chemical drugs were also found to up - regulate several IFN - inducible gene family members (including RIG - G) through production of type I IFNs (37, 38), further indicating that the induction of RIG - G by ATRA in NB4 cells was tightly related with an IFNα autocrine pathway.