Type 1 diabetes mellitus (T1D) begins with
autoimmune destruction of insulin producing cells in the pancreas, usually in children.
In their new Stem Cells Translational Medicine study they show how this strategy can be safely applied to replace the pancreatic cells lost via
autoimmune destruction in type 1 diabetes mellitus (T1D)[1].
This pathway is key in our body's ability to fight off pathogens, but its «dark side» is that it
facilitates autoimmune destruction in conditions such as multiple sclerosis (MS), psoriasis, and rheumatoid arthritis.
Type 1 diabetes mellitus (T1D) is characterized
by autoimmune destruction of the insulin producing - cells of pancreatic islets.
The origin varies from person to person, and could step
from autoimmune destruction (Hashimoto's thyroiditis) or secondary to high cortisol, or even from endocrine disruptors like Bisphenol A or flame retardants.
Autoimmune destruction of insulin - producing pancreatic β - cells is recognized as the key pathogenic feature of type 1 diabetes in patients and in the NOD mouse model (18).
Autoimmune destruction of oligodendrocytes and their fatty contents gives rise to multiple sclerosis.
Type 1 diabetes is a consequence of
the autoimmune destruction of insulin - producing beta cells in the pancreas.
The major cause of Addison's disease is
autoimmune destruction.
Dry eye can be caused by a variety of causes, but the most common cause is
an autoimmune destruction of the lacrimal glands around the eye.
An autoimmune destruction of the thyroid gland which affects more than 50, dog breeds.
Granulomatous sebaceous adenitis: a disease of sebaceous (sweat) skin glands characterized by reactive tissue growth and
autoimmune destruction of the sebaceous glands.
The disease occurs due to
autoimmune destruction of the insulin - producing β - cells of the pancreas, resulting in a complete loss of the ability to produce insulin, a hormone necessary for survival.