Sentences with phrase «autoimmune encephalomyelitis»
CB2 cannabinoid agonists such as WIN55,212 - 2 inhibit experimental autoimmune encephalomyelitis (EAE), an animal model of MS, by mediating apoptosis of the encephalitogenic cells that induce brain inflammation (41).
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In the mouse model of MS, experimental autoimmune encephalomyelitis (EAE), positive effects of modified fasting and ketogenic nutrition on disease onset and clinical course in animals have been observed in several studies.
In addition, WEHI - 435 (N -(2 -(4 - amino - 3 -(p - tolyl)-1 H - pyrazolo [3,4 - d] pyrimidin -1-yl)-2-methylpropyl) isonicotinamide) interfered with cytokine production in vitro and in vivo and ameliorated experimental autoimmune encephalomyelitis in mice (Nachbur et al., 2015).
One study showed that VPA could inhibit experimental autoimmune encephalomyelitis in mouse model (28).
In two other studies that assessed the therapeutic effect of VPA on experimental colitis or experimental autoimmune encephalomyelitis, the investigators showed that VPA was effective and safe up to 400 mg / kg / d (28, 29).
The antiepileptic drug valproic acid restores T cell homeostasis and ameliorates pathogenesis of experimental autoimmune encephalomyelitis.
IL - 17A secretion by CD8 + T cells supports Th17 - mediated autoimmune encephalomyelitis.
And CD4 + T - cells in the blood vessels of vaccinated mice were rare, contrasting with experimental autoimmune encephalomyelitis (EAE) mice, which are a positive control model of T - cell - mediated CNS autoimmunity.
Berghmans N, Nuyts A, Uyttenhove C, Van Snick J, Opdenakker G, Heremans H. Interferon - gamma orchestrates the number and function of Th17 cells in experimental autoimmune encephalomyelitis.
Mice with a disrupted IFN - gamma gene are susceptible to the induction of experimental autoimmune encephalomyelitis (EAE).
IL - 17RC is required for IL - 17A - and IL - 17F - dependent signaling and the pathogenesis of experimental autoimmune encephalomyelitis.
Functional interleukin - 17 receptor A is expressed in central nervous system glia and upregulated in experimental autoimmune encephalomyelitis.
Effector and suppressor roles for LFA - 1 during the development of experimental autoimmune encephalomyelitis.
Intercellular adhesion molecule - 1 expression is required on multiple cell types for the development of experimental autoimmune encephalomyelitis.
Suppression of experimental autoimmune encephalomyelitis by extracellular adherence protein of Staphylococcus aureus.
IL - 17 plays an important role in the development of experimental autoimmune encephalomyelitis.
Berard JL, Wolak K, Fournier S, David S. Characterization of relapsing - remitting and chronic forms of experimental autoimmune encephalomyelitis in C57BL / 6 mice.
Domingues HS, Mues M, Lassmann H, Wekerle H, Krishnamoorthy G. Functional and pathogenic differences of Th1 and Th17 cells in experimental autoimmune encephalomyelitis.
Administration of murine stromal vascular fraction ameliorates chronic experimental autoimmune encephalomyelitis.
Hyaluronan Anchored to Activated CD44 on CNS Vascular Endothelial Cells Promotes Lymphocyte Extravasation in Experimental Autoimmune Encephalomyelitis.
Astrocyte CCL2 sustains immune cell infiltration in chronic experimental autoimmune encephalomyelitis.
Low Dose Naltrexone Treatment of Established Relapsing - Remitting Experimental Autoimmune Encephalomyelitis.
Comparison of human adult stem cells from adipose tissue and bone marrow in the treatment of experimental autoimmune encephalomyelitis.
Hyaluronan Anchored to Activated CD44 on CNS Vascular Endothelial Cells Promotes Lymphocyte Extravasation in Experimental Autoimmune Encephalomyelitis % U http://www.jbc.org/content/early/2012/08/03/jbc.M112.356287.short.
Investigators (Fumitaka Sato, PhD, et al) tested resveratrol in autoimmune and viral models of MS.. In the autoimmune model, experimental autoimmune encephalomyelitis (EAE) was induced in 6 - week - old mice using myelin oligodendrocyte glycoprotein (MOG) 35 - 55 peptide.
The scientists performed pre-clinical trials using experimental autoimmune encephalomyelitis, a pre-clinical model for human multiple sclerosis.