Sentences with phrase «autoimmune response directed»
In their latest work, reported online in the Journal of Clinical Investigation, the scientists analyzed blood from such mice and identified two types of autoimmune response directed specifically against the protein, with the first response directed by a specialized kind of immune system cells called T cells and the second by antibodies.
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Previous research has indicated that salt may alter the autoimmune response, which is implicated in the development of multiple sclerosis (MS), but it is not clear if it has any direct effect on the course of the disease itself.
It included a 1994 report from the Institute of Medicine that said it was biologically plausible for a vaccine to «induce... an autoimmune response... by nonspecific activation of the T cells directed against myelin proteins.»
When the amino acid sequence is homologous between the target antigen, such as gluten, against which the immune system is mounting a response, and tissue proteins, such as the thyroid tissue, a case of mistaken identity occurs, and the immune response can become directed against self tissues, manifesting as autoimmune disease (Hashimoto's thyroiditis in this instance).
Autoimmune diseases are characterized by tissue damage and loss of function due to an immune response that is directed against specific organs.