Sentences with word «autologous»

The use of autologous stem cells from patients with heart disease should be modified.

The results could help improve the use of autologous stem cells — those drawn from the patients themselves — in cardiac therapy, Prof. Leor said.

Finally, the future success of autologous transplantation of genetically repaired or in vitro expanded organoids in patients, abolishing the need for allogeneic donors and for lifelong immunosuppression, is dependent on a significant improvement in engraftment efficiency.

For example, we have no information about how these newly - generated HPCs will compete with autologous bone marrow cells for hematopoietic niches in the recipient mice.

Conditional survival and excess mortality after high - dose therapy with autologous stem cell transplantation for adult refractory or relapsed Hodgkin lymphoma in Norway.

These data suggest that CXCR4 - specific ZFNs may prove useful in establishing resistance to CXCR4 - tropic HIV for autologous transplant in HIV - infected individuals.

While some previous studies found that maintenance lenalidomide after autologous hematopoietic stem cell transplant improved overall survival for newly diagnosed multiple myeloma patients, others showed no benefit to this approach.

Therapy With Autologous Adipose - Derived Regenerative Cells for the Care of Chronic Ulcer of Lower Limbs in Patients with Peripheral Arterial Disease (March 20, 2013) in Journal of Surgical Research.

Sustained high - level polyclonal hematopoietic marking and transgene expression 4 years after autologous transplantation of rhesus macaques with SIV lentiviral vector - transduced CD34 + cells.

Peripheral blood stem cells are generally used in autologous transplantations, while either marrow or peripheral blood stem cells are used in allogeneic transplantations.

A second trimer, B41 SOSIP.664, also induced a strong autologous tier 2 NAb response in rabbits.

Homologous blood transfusions (that is, from another person) are detectable via DNA screening, but there is still no reliable test for autologous blood transfusion.

There is little risk of rejection of a patient's own stem cells following autologous transplant.

«Meta - regression analyses failed to demonstrate any association between CR or (CR or VGPR) with either overall survival or progression - free survival both in patients receiving autologous stem cell transplant [ASCT] and in non-ASCT patients.»

Journal reference: JAMA, C - Peptide Levels and Insulin Independence Following Autologous Nonmyeloablative Hematopoietic Stem Cell Transplantation in Newly Diagnosed Type 1 Diabetes Mellitus

Re-directed Autologous T cell Therapy for drug resistant or refractory CD20 + B cell lymphoma Overview: In this approach, immune cells (known as T cells) are taken from the peripheral blood, genetically modified in the laboratory to express a receptor that recognizes B cells, and then expanded to produce large numbers of tumor specific T cells outside -LSB-...]

The treatment in the current study, called autologous hematopoietic stem cell transplantation (AHSCT), was given to patients with advanced forms of the disease that had failed to respond to other medications.

Dr. Goodman is also involved in collaborative efforts with the San Antonio Bone Marrow Transplant Center to study the outcome of allogeneic bone marrow transplants following a relapse from autologous bone marrow transplants.

37 patients received autologous MSCs via intrathecal injection, rather than direct spinal cord injection, in two monthly doses, and were then followed up at 6 months with responders (ALS - R) and non-responders (ALS - N) identified using the revised ALS functional rating scale (ALSFRS - R).

The researchers raise concern that current medical reimbursement discourages surgeons from offering autologous reconstruction.

This may entail making small holes in the bone to allow new cartilage to grow (microfracture), taking cartilage from another part of the athlete's knee and transplanting it into the defect (osteochondral autograft transfer), taking cartilage cells from the knee and then having them grown in a lab for later re-implantation (autologous chondrocyte implantation), or taking cartilage from a person who has passed away and placing it in the defect (osteochondral allograft transfer).

Additionally, non-interventional treatments such as Autologous Conditioned Plasma (ACP), stem cell therapy, and rehabilitation / conditioning are proven treatment modalities that are coupled with surgical intervention or used alone as primary treatment.

Dane Tatarniuk, MS (VMED) Adviser: Dr. Troy Trumble Thesis: Autologous conditioned serum and subsequent synovial fluid concentrations of cytokines, matrix metalloproteinases, and tissue inhibitors of metalloproteinases after injection into equine osteoarthritic distal interphalangeal joints.

This is the «show reel» of Dr Haluk Deda, a Turkish neurosurgeon who is setting up shop in Dubai, where he plans to offer autologous stem cell transplants to treat chronic spinal cord injuries and ALS, a condition with no known cure that generally leads to death within three to five years of diagnosis.

IFN - α Augments NK - mediated Antibody - Dependent Cellular Cytotoxicity (ADCC) of HIV - 1 Infected Autologous CD4 + T Cells Regardless of MHC - I Downregulation.

Tan J, Wu W, Xu X, Liao L, Zheng F, Messinger S, Sun X, Chen J, Yang S, Cai J, Gao X, Pileggi A, Ricordi C. Induction therapy with autologous mesenchymal stem cells in living - related kidney transplants: a randomized controlled trial.

While undergoing treatment in what was described as a clinical trial, three elderly patients with macular degeneration were blinded after being administered a treatment based on autologous adipose tissue.

An important impact of the Hematopoietic Stem - Cell Gene Therapy described in the paper, is that it allows for the use of autologous CD34 + cells, thereby avoiding complications associated with allogeneic transplantation.

Review of «Allogeneic MSCs and recycled autologous Chondrons mixed in a one - stage cartilage cell transplantation: A first - in - man trial in 35 patients» from STEM CELLS by Stuart P. Atkinson

Allogeneic MSCs and Recycled Autologous Chondrons Mixed in a One - Stage Cartilage Cell Transplantion: A First - in - Man Trial in 35 Patients.

Intracoronary autologous cardiac progenitor cell transfer in patients with hypoplastic left heart syndrome: the TICAP prospective phase 1 controlled trial.

Cellular Component: Limbal epithelial cells Matrix Component: Basement membrane of HAM It is a 4 cm2 denuded human amniotic membrane with cultured autologous limbal biopsy explants with 80 % of the cells positive for p63 marker.

I have worked in 3 different biotech companies to make autologous vaccines.

When autologous (self - donated) lung - derived mensenchymal stem cells (LMSCs) were transplanted endoscopically into 13 adult female sheep modeled with emphysema, post-transplant...

In a landmark study, Hirsch et al. used engineered autologous skin stem cells to replace more than 80 % of the epidermis of a critically ill 7 - year - old boy.

Should all patients with Hodgkin lymphoma who relapse after autologous SCT be considered for allogeneic SCT?

«The ability to control autoimmunity by autologous HSCT [hematopoietic stem cell transplantation] has been demonstrated in other treatment - refractory autoimmune conditions, including neurologic diseases.

A new study published online by JAMA Neurology examines the long - term outcomes of patients with aggressive forms of multiple sclerosis (MS) who failed to respond to standard therapies and who underwent autologous hematopoietic stem cell transplantation using their own stem cells.

Rodrigo Gouvea Rosique, MD, PhD, of Master Hospital of Plastic Surgery in Goiânia, Goiás, Brazil, and colleagues outline their safe and effective technique of «gluteoplasty with autologous fat tissue» for buttocks augmentation.

Although autologous cell transplantation circumvents the need for immunosuppressive treatment, it is not always available or most effective.

A major part of CCTD, led by its interim director Dr. Gordon Weir, is the participation and coordination of program activities with the Boston Autologous Islet Replacement Therapy (BAIRT) program.