RepliCel Life Sciences Inc. (OTCQB: REPCF)(TSX.V: RP), a clinical stage regenerative medicine company focused on the development of
autologous cell therapies, announced today the publication of a paper out of the University of Calgary in conjunction with co-authors from Kyoto University and the University of North Carolina, which further validates the company's ongoing clinical research using dermal sheath cup (DSC) cells to reverse the effects of pattern baldness.
Autologous cell therapies require a fundamentally different manufacturing approach, and we did not identify any DSTs designed specifically for such processes.
Manufacturing Models Permitting Roll - Out / Scale - Out of Clinically Led
Autologous Cell Therapies: Regulatory and Scientific Challenges for Comparability.
In part 2, we continue to analyze manufacturing costs of
an autologous cell therapy.
RepliCel's
autologous cell therapy, RCS - 01, to be investigated as a potential treatment for aged and UV - damaged skin.
Not exact matches
HSCT is effectively used today as a form of «replacement»
therapy for patients with hard - to - treat blood cancers, providing healthy
cells from either the patient (
autologous transplantation) or from a donor (allogeneic transplantation) to better equip patients to fight the disease on their own.
Dr. Stoddart's main research focus is using
autologous stem
cells and gene transfer to repair musculoskeletal tissues using a
cell therapy approach.
Results from a clinical trial investigating a new T
cell receptor (TCR)
therapy that uses a person's own immune system to recognize and destroy cancer
cells demonstrated a clinical response in 80 percent of multiple myeloma patients with advanced disease after undergoing
autologous stem
cell transplants (ASCT).
«Previous studies have shown that a threshold percentage of limbal stem
cells (which are responsible for replenishing the cornea) is required for successful corneal
autologous therapy,» says co-first author Tom Bongiorno, a graduate student in bioengineering at Georgia Tech.
The
therapy is approved by the U.S. Food and Drug Administration for relapsed or treatment - resistant Hodgkin lymphoma, and it is commonly prescribed to patients whose disease has progressed after
autologous stem
cell transplant, a procedure that replenishes the bone marrow with the patient's own healthy stem
cells after
therapy.
A national study on conditional survival, excess mortality and second cancer after high dose
therapy with
autologous stem
cell transplantation for non-Hodgkin lymphoma.
Conditional survival and excess mortality after high - dose
therapy with
autologous stem
cell transplantation for adult refractory or relapsed Hodgkin lymphoma in Norway.
Tan J, Wu W, Xu X, Liao L, Zheng F, Messinger S, Sun X, Chen J, Yang S, Cai J, Gao X, Pileggi A, Ricordi C. Induction
therapy with
autologous mesenchymal stem
cells in living - related kidney transplants: a randomized controlled trial.
Anke Theil (Bonifacio, TUD)-- «Exploring the therapeutic potential of
autologous cord blood T regulatory
cell therapy for type 1 diabetes» (2012)
In a previous study by the same group 78,
autologous culture - expanded MSC were infused to breast cancer patients to investigate whether MSC would enhance the engraftment of peripheral blood stem
cells after myeloablative
therapy.
Passive immunization, herein referred to as adoptive T
cell therapy, is the transfusion of
autologous or allogeneic T
cells into tumor - bearing hosts, i.e., patients.
For the first time, researchers demonstrate long term success of a
cell replacement
therapy using
autologous induced pluripotent stem
cell derivatives
In 2016, the Food and Drug Administration (FDA), the branch of government charged with regulating cellular
therapies, took action to address these issues, proposing revised guidelines that could change how stem
cells, especially
autologous stem
cells, are regulated.
Embryonic
cell lines and
autologous embryonic stem
cells generated through therapeutic cloning have also been proposed as promising candidates for future
therapies.
For instance, during emergency care, allogeneic
therapy is usually the only relevant option due to the time constraints of
autologous cell expansion.
The
therapy from Trinity Clinic Fukuoka involves 10 intravenously administered doses of 200 million
autologous adipose tissue - derived mesenchymal stem
cells.
Therapy With
Autologous Adipose - Derived Regenerative
Cells for the Care of Chronic Ulcer of Lower Limbs in Patients with Peripheral Arterial Disease (March 20, 2013) in Journal of Surgical Research.
Furthermore, later - stage DSTs (such as those focusing on regulation) or higher level strategic tools (such as those focusing on portfolio management) might be readily applied to both
autologous and allogeneic
cell therapies.
The really important questions are whether this
therapy can be given safely; early in the disease course; and as second - line treatment, replacing an
autologous stem
cell transplant.
The other type of
therapy is
autologous mesenchymal stem
cell transplantation.
MediVet's Stem
Cell therapy allows our veterinarians to isolate stem
cells from your pet's own (
autologous) fat tissue, wake them up and reintroduce them directly into damaged areas.
This is called
Autologous Therapy when the stem
cells come from your own body's tissues.
Additionally, non-interventional treatments such as
Autologous Conditioned Plasma (ACP), stem
cell therapy, and rehabilitation / conditioning are proven treatment modalities that are coupled with surgical intervention or used alone as primary treatment.
After learning about
autologous stem
cell therapy and how it could help her, we raised money to help the rescue pay for her treatment.
Re-directed
Autologous T
cell Therapy for drug resistant or refractory CD20 + B
cell lymphoma Overview: In this approach, immune
cells (known as T
cells) are taken from the peripheral blood, genetically modified in the laboratory to express a receptor that recognizes B
cells, and then expanded to produce large numbers of tumor specific T
cells outside -LSB-...]
Core Paws learned about an
Autologous Stem
Cell Therapy via MediVet Biologics that was working miracles in animals with arthritis.
After experiencing how
autologous adult stem
cell therapy helped a loved one struggling with Multiple Sclerosis regain their life quality, Stemedix was founded with the determination to help offer this alternative
therapy to others around the world suffering from debilitating diseases.