Sentences with phrase «available drugs»

Currently available drugs used for heart failure work at the surface of heart cells.

Our results suggest that readily available drugs could help protect neurons against some of the damages inflicted by this illness.

Impact: The discovery of LC pathways of major effect would be immediately pursued with new therapies using current available drugs.

If such systems became commonly available, you would no longer have to guess which of several available drugs would work best for you.

This also included a virus isolate resistant against most available drugs.

Researchers have developed an opioid compound that targets specific pain receptors in cells, but without producing the addictive qualities typical of currently available drugs.

By screening commercially available drugs currently being used for other diseases, researchers found vorinostat to be an effective anti-seizure drug in zebrafish and mouse models.

Though it still has to be shown effective in humans with the disease, this paper provides a testable method of optimizing currently available drugs for melanoma treatment.

Some of the infections can be treated with available drugs, but they are not always effective and side effects can be significant.

Currently, Dr. Ocal is trying to find the best combination of available drugs that generates the largest reduction in tumor growth early on.

In the Netherlands, based on research reported in 2016 in Science Translational Medicine, Clevers and colleagues are already using personalized gut organoids, derived from rectal biopsies, to test whether cystic fibrosis patients will benefit from available drugs.

«Now that we've tested already available drugs, the published results enable us to move on to clinical trials relatively quickly, which is very good news indeed,» says Dr Malin Wickström, one of the researchers behind the study.

While immunotherapy has shown great promise, the currently available drugs work for only a minority of patients.

Available drugs only marginally affect disease severity, making Alzheimer's disease effectively untreatable.

The alarmist prediction that cheap available drugs could lead to an addiction rate of 75 percent of regular users simply ignores the fact that 35 to 40 million Americans are already using some drugs and that only 3 percent become addicts.

Eventually those robust microbes can outsmart available drugs, and even pass on survival instructions to other bacterial strains.That's why most doctors — along with the World Health Organization and the U.S. Centers for Disease Control and Prevention — urge patients to always complete prescribed drug courses, even after they feel better.

«Next, we will explore the therapeutic implications of our discovery by repurposing available drugs that block these adenosine receptors and are well tolerated in humans.»

People at high risk of cancer may soon be advised to take readily available drugs such as aspirin to reduce their chances of succumbing to one of the world's biggest killers.

Therefore, investigators wanted to assess whether acetaminophen, a popular and readily available drug similar in action to ibuprofen with fewer gastrointestinal side effects might also reduce the risk of AMS.

RG7916 is an orally available drug that directly targets the underlying molecular deficiency of SMA by modulating SMN2 splicing to increase expression of full - length SMN2 mRNA and SMN protein from the SMN2 gene.

Things have changed quite a bit since then, and Brenda is now receiving one of the newest available drugs for someone with her condition.

The currently available drugs include:

In addition to medications to relieve GERD, there are a slew of widely available drugs to treat post-nasal drip and sore throat directly.

«The use of TMS could be a major step forward in patients in whom presently available drug treatment is ineffective, poorly tolerated, or contraindicated,» Hans - Christoph Diener, MD, of University Hospital Essen, in Germany, noted in an editorial accompanying the study.

Explain why protocols should be based on available drugs, patient health, pain level, behavior, and planned procedures

Co-researcher Professor Carola Vinuesa from JCSMR said the new findings opened the door to using available drugs to improve therapies for lymphoma, autoimmunity and immunodeficiency disorders.

The study, published December 4 in Nature Communications, also suggests that a class of commercially available drugs could be used to dampen ADAR1 activity, and ultimately prevent progression or relapse in multiple myeloma.

Rainer Krähenmann considers research into novel approaches to treatment very important, because current available drugs for the treatment of depression and anxiety disorders are not effective in all patients and are often associated with unwanted side effects.

Already available drugs may stave off and even reverse debilitating symptoms

Available drugs work at the surface of heart cells, defending them from additional damage by dampening external stressors, such as the hormone adrenaline.

The long - term efficacy of drug treatments is unknown in terms of the accumulation of disability and the prognosis of relapsing - remitting MS.. A better understanding of the neuroprotective effects of available drugs and newer compounds is needed,» the authors conclude.

«Unlike other currently available drugs for inflammatory bowel disease, ozanimod can be orally administered and does not suppress the immune system to the point of increasing likelihood of infection or cancer.»

«Our findings may allow us to modify receptor signalling in ways that far exceed simple receptor blockade or activation, as achieved with currently available drugs.

With many strains of bacteria that mutate and become immune to available drugs, and with emerging of new pathogens, there is a huge demand for new antibacterial medication.

Researchers at the University of Illinois at Chicago have now identified a small drug molecule that can clear the HSV - 1 infection in the cells of the cornea — the clear outer layer of the eyeball — and works completely differently than the currently - available drugs, making it a promising potential option for patients who have developed resistance.

Currently available drugs to treat HSV - 1 infection work by preventing the virus from producing the proteins it needs to replicate and are known as nucleoside analogs.

Such absolute resistance to all available drugs, though incredibly rare, was a «nightmare scenario,» says Daniel Kadouri, a micro-biologist at Rutgers School of Dental Medicine in Newark, N.J.

«This research is highly significant as it implies that a commercially available drug, amphotericin B, which has never been used before for patients with gliomas, may be a novel treatment to consider in future trials of patients with this frequently lethal cancer,» says Dr. Rutka.

A new study demonstrated that using two currently available drugs could be an effective treatment for the majority of lung cancers.

At the same time, bacteria have continued to evolve resistance to all of the currently available drugs, creating the current critical situation.

There are 850,000 people in the UK living with dementia, and currently available drugs are only able to treat the symptoms of dementia, rather than slowing its progression.

«If you could take a patient's cells and within days have microtumors that you could use to screen all the available drugs, then an oncologist would be able to prescribe a treatment that's tailor - made for the patient that targets both the tumor cells and these elusive cancer stem cells that currently we can't see.

The scientists say the next step is to test several currently available drugs that more specifically block the A2A receptors for their memory enhancing potential.

But the authors suggest it could be of great value to people fighting MRSA, tuberculosis, and infections with rare - but - nasty Enterococcus bacterial strains that aren't responding to available drugs.

Monk also said that Gpr56 belongs to a large class of cell receptors that are common targets for many commercially available drugs, making the protein attractive for further research.

«There are currently virtually no treatments for dilated cardiomyopathy targeted to genetic changes, so the finding that commercially available drugs may be effective for patients with childhood - onset, RAF1 - induced DCM is a remarkable advance,» said Bruce Gelb, MD, Director and Gogel Family Professor of the Mindich Child Health and Development Institute at Mount Sinai and senior author.