The small increase in the high - dose group did not translate into beneficial effects because authors found no difference between the three study groups for changes in spine,
average total - hip,
average femoral neck or total - body
bone mineral density, trabecular
bone score, muscle mass or sit - to - stand tests.
Data from the substudy presented today illustrate that
bone mineral density decreased a measurable but clinically insignificant amount over the course of a year in young adult males and transgender participants with an
average age of 24 taking a protective amount of PrEP.