Sentences with phrase «avoid other effects»

To prevent this conversion and avoid other effects of oxidative stress, we like to increase these binding proteins.

Not exact matches

Important factors that could cause actual results to differ materially from those reflected in such forward - looking statements and that should be considered in evaluating our outlook include, but are not limited to, the following: 1) our ability to continue to grow our business and execute our growth strategy, including the timing, execution, and profitability of new and maturing programs; 2) our ability to perform our obligations under our new and maturing commercial, business aircraft, and military development programs, and the related recurring production; 3) our ability to accurately estimate and manage performance, cost, and revenue under our contracts, including our ability to achieve certain cost reductions with respect to the B787 program; 4) margin pressures and the potential for additional forward losses on new and maturing programs; 5) our ability to accommodate, and the cost of accommodating, announced increases in the build rates of certain aircraft; 6) the effect on aircraft demand and build rates of changing customer preferences for business aircraft, including the effect of global economic conditions on the business aircraft market and expanding conflicts or political unrest in the Middle East or Asia; 7) customer cancellations or deferrals as a result of global economic uncertainty or otherwise; 8) the effect of economic conditions in the industries and markets in which we operate in the U.S. and globally and any changes therein, including fluctuations in foreign currency exchange rates; 9) the success and timely execution of key milestones such as the receipt of necessary regulatory approvals, including our ability to obtain in a timely fashion any required regulatory or other third party approvals for the consummation of our announced acquisition of Asco, and customer adherence to their announced schedules; 10) our ability to successfully negotiate, or re-negotiate, future pricing under our supply agreements with Boeing and our other customers; 11) our ability to enter into profitable supply arrangements with additional customers; 12) the ability of all parties to satisfy their performance requirements under existing supply contracts with our two major customers, Boeing and Airbus, and other customers, and the risk of nonpayment by such customers; 13) any adverse impact on Boeing's and Airbus» production of aircraft resulting from cancellations, deferrals, or reduced orders by their customers or from labor disputes, domestic or international hostilities, or acts of terrorism; 14) any adverse impact on the demand for air travel or our operations from the outbreak of diseases or epidemic or pandemic outbreaks; 15) our ability to avoid or recover from cyber-based or other security attacks, information technology failures, or other disruptions; 16) returns on pension plan assets and the impact of future discount rate changes on pension obligations; 17) our ability to borrow additional funds or refinance debt, including our ability to obtain the debt to finance the purchase price for our announced acquisition of Asco on favorable terms or at all; 18) competition from commercial aerospace original equipment manufacturers and other aerostructures suppliers; 19) the effect of governmental laws, such as U.S. export control laws and U.S. and foreign anti-bribery laws such as the Foreign Corrupt Practices Act and the United Kingdom Bribery Act, and environmental laws and agency regulations, both in the U.S. and abroad; 20) the effect of changes in tax law, such as the effect of The Tax Cuts and Jobs Act (the «TCJA») that was enacted on December 22, 2017, and changes to the interpretations of or guidance related thereto, and the Company's ability to accurately calculate and estimate the effect of such changes; 21) any reduction in our credit ratings; 22) our dependence on our suppliers, as well as the cost and availability of raw materials and purchased components; 23) our ability to recruit and retain a critical mass of highly - skilled employees and our relationships with the unions representing many of our employees; 24) spending by the U.S. and other governments on defense; 25) the possibility that our cash flows and our credit facility may not be adequate for our additional capital needs or for payment of interest on, and principal of, our indebtedness; 26) our exposure under our revolving credit facility to higher interest payments should interest rates increase substantially; 27) the effectiveness of any interest rate hedging programs; 28) the effectiveness of our internal control over financial reporting; 29) the outcome or impact of ongoing or future litigation, claims, and regulatory actions; 30) exposure to potential product liability and warranty claims; 31) our ability to effectively assess, manage and integrate acquisitions that we pursue, including our ability to successfully integrate the Asco business and generate synergies and other cost savings; 32) our ability to consummate our announced acquisition of Asco in a timely matter while avoiding any unexpected costs, charges, expenses, adverse changes to business relationships and other business disruptions for ourselves and Asco as a result of the acquisition; 33) our ability to continue selling certain receivables through our supplier financing program; 34) the risks of doing business internationally, including fluctuations in foreign current exchange rates, impositions of tariffs or embargoes, compliance with foreign laws, and domestic and foreign government policies; and 35) our ability to complete the proposed accelerated stock repurchase plan, among other things.
While Greenblatt was obviously looking to avoid any connection between Trump's long stint at NBC and the fact that the billionaire is now one election away from the White House, other media executives have previously spoken more freely about the positive effect Trump's political career has had on TV ratings.
Other requirements will also go into effect if the program passes: permit holders must yield to city buses, avoid certain streets, and provide ridership and location data for enforcement and program adjustments.
This is, of course, a best - practice strategy — however, what it fails to take into consideration, is that within an artificial manipulation of a link strategy to avoid filters, there are also other patterns that take effect that Google might penalize in future iterations of their algorithm.
In an ever - shrinking world of instant communication and information overload, we can not avoid being exposed to other ways of life, and they will have their effect on us.
Apple pies and other baked goods with apples should be avoided, as they likely contain too much sugar which will counteract the effects of eating the apple itself.
Coconut oil, according to the «Blood Type Diet», Flocculates serum or precipitates serum proteins - for blood types A, and B, (both secreter and non secreter) type AB should AVOID: as it Enhances effect of other food toxins.
Having said that, I am not aware of any blaring reasons to avoid it other than complete lack of knowledge to its effects on lactating women and their infants.
A number of other small studies support this idea, known as «immunotherapy,» for overcoming various types of food allergies, but it's still unclear how long the effects last — it may be that people have to keep consuming the allergen regularly to avoid becoming allergic again — and exposing allergic individuals to their offending allergens can, of course, be risky.
The instant runoff system is considered a very good voting system when choosing between multiple options because it avoids the spoiler effect (e.g. two similar options stealing each other votes so a 3rd candidate who is actually less popular than them wins), doesn't discourage votes for options perceived as underdogs and leads to a compromise most people can agree to.
Because people with certain digestive conditions, such as colitis, are often warned to avoid too much roughage in their diets, future research may include determining the best ways for people to consume the broccoli — or other vegetables with similar effects — to receive the same health benefits, without causing any other associated digestive problems from the fibrous vegetables.
Yet unlike APR - 246, it would eventually fall off and so would avoid making permanent changes to other proteins in the body, reducing the risk of side effects.
Unlike other human antibodies under investigation that recognize both Zika and the closely related dengue virus, the antibodies used in this study exclusively target Zika, demonstrating a high specificity that could be important in avoiding potential side effects — such as enhanced dengue infection in regions where both viruses are endemic.
There is also a requirement to accommodate a low main radio frequency (100 MHz) and to lengthen the electron bunches to alleviate multiple scattering within the bunches as well as to avoid collective effects driven by, amongst other effects, the chamber wall resistivity.
It would also avoid the difficulty found with nonspecific drugs, which interfere with other hormonal receptors, causing side effects such as thrombosis and fluid retention.
This latest effort, led by researchers at Oregon Health and Science University, also succeeded in avoiding unintended effects — something that's plagued other researchers.
Marijuana's promise of pain relief is impressive in its own right, but when you add in the possibility of avoiding other drugs, and their side effects, it starts to look very appealing.
She applauds the new work, noting that Ludwig and colleagues used apt statistical models to try to avoid confounding effects and excluded subjects with other risk factors such as gestational diabetes or extremely high birth weight.
Their postoperative use has expanded with the recent development of intravenous formulations and because NSAIDs avoid the adverse effects of opioid pain relievers such as respiratory depression, impaired motility of the gastrointestinal tract and others, according to background in the study.
This can be useful to recommend that these tumors do not be conformed to surgery and determine that it will probably be necessary to administer adjuvant chemotherapy in other words, in those tumors with a more «benign» epigenetic pattern; surgery alone may be curative, thus avoiding the side effects of chemotherapy, «concludes the researcher.
Similar to a trojan horse, the drug enters the liver with a trick: It uses the pancreatic hormone glucagon as vehicle to shuttle thyroid hormone T3 the live while keeping it away from other organs, thereby improving cholesterol and lipid metabolism while avoiding typical side effects of thyroid hormone.
The authors note that experiences of other countries that have overcome financial crises, such as Iceland and Finland, suggest that by ring - fencing health and social budgets, governments can avoid some of the harmful effects of crisis taking their toll on the health of their populations.
Newer drugs like Celebrex and Vioxx, which specifically block one of these enzymes, COX - 2 — and thereby avoid upset stomachs and other side - effects — are popular arthritis medications (they even outsell Viagra).
Beyond preparing for the inevitable, the report also calls for climate mitigation, including implementing the 2015 Paris Agreement in order to have «any hope of avoiding catastrophic effects from sea - level rise and other outcomes of global warming.»
Reporting only aggregated adherence rates could create an incentive to avoid groups with worse outcomes rather than undertaking interventions to improve their care.41 Some health plans or clinicians may avoid enrolling minority patients, for whom performance rates are typically lower.42, 43 Stratifying performance rates by race, ethnicity, or other demographic characteristics may mitigate such undesired effects by not penalizing organizations that disproportionately treat minority patients.
The other 99 % of scientists fear for our future based on thousands of scientific studies and believe that we need to change what we're doing to avoid drastically harmful effects.
As calculations are based on DNA sequence data and not physical measurements, it can tease apart the genetically determined component of gene expression from the effects of the trait itself (avoiding reverse causality) and other factors such as environment.
As with other types of transplantation, the challenge with islet transplantation is to avoid rejection of the donated organ and to balance that goal against side effects from the drugs needed to control the immune system.
Scholar Rock has demonstrated that SRK - 015 selectively binds to the latent forms of myostatin, inhibiting activation while avoiding interaction with other closely related members of the TGFβ superfamily that may lead to unintended adverse effects.
The decrease in leptin levels is accompanied by several other negative effects which everyone wanting to lose fat would like to avoid, such as overall metabolic slow - down (often called metabolic adaptation), a decrease in energy and strength levels, increase in appetite, reduced sense of well - being and decreased motivation.
Just avoid sweetened varieties to save yourself the negative effects of added sugar and other additives.
Smart drugs, on the other hand, have potentially dangerous side effects (especially when used off - label or by someone they were not prescribed to) and should generally be avoided, especially without the oversight of a trained doctor or medical professional.
Pre workout side effects and other problems can be avoided if you include taurine in your supplement stack.
On the other hand, although Menoquil does not cause any side effect, women who have a known allergy to any of Menoquil's ingredients should avoid taking this product.
I do not have any joint issues or any other side effects, not even stomach pain from eating TONS of sundried tomatoes, eggplant and paprika at all, but since reading in this well written article that tomatoes are to be avoided by people with leaky gut, I am at least cutting them out of my diet over the next couple months as I address this issue.
Keep reading about all the amazing Maca health benefits mentioned above and many many others as well as some Maca side effects that you want to avoid by purchasing only the safest Maca prime products and by taking the right dosage of Maca, and decide for yourself if Maca is right for you!
Decide which exercises you are going to do and mimic these movements in a modified way (for example; if you are going to jump squats, do 10 to 12 regular squats first, and be sure to use good form with squats to avoid hemorrhoids and other untoward effects).
You can not only help yourself by avoiding side effects of medical treatment, but also potentially prevent breast or other cancer recurrence.
On the other hand, diabetics taking drugs to control blood sugar levels should avoid consuming carambola in therapeutic doses, since it can potentiate the hypoglycemic effect of the medication.
I personally avoid eating too much dairy because I know it has a negative effect on my condition while others have to avoid more foods.
The other side effects are high blood pressure, inefficient cholesterol levels so people with such clinical conditions should avoid its usages.
For others, the side effects of some allergy medications are reason enough to avoid them.
Many dentists warn their patients to avoid all alcoholic beverages due to their acidic effect on gums and teeth, but wine isn't like all the other drinks.
No need to avoid it in fruit or vegetables, the fiber, antioxidants and other solids regulate the metabolism and prevent the harmful effects.
For those suffering from lead or other heavy metal poisoning, a protective diet that avoids processed foods and emphasizes the central components of a nutrient - dense and antioxidant - rich WAPF - style diet is essential (see sidebar).21 Nutritional status shapes susceptibility to lead toxicity in important ways, affecting lead's intestinal absorption; its mobilization, distribution and retention in the body; and excretion.22 Because oxidative stress is a likely mechanism explaining some of lead's toxic actions, some investigators have begun to explore whether natural antioxidants and trace minerals may help mitigate lead - induced cell damage.17 Specifically, researchers in Spain found that administration of vitamins A, B6, C and E along with zinc modulated some of the negative effects of lead exposure in rat pups, confirming the influence of nutritional factors on health outcomes following lead exposure.17 Vitamin D also should be a major component of a protective diet.
Although Sucralose doesn't seem to have the same effects as other artificial sweeteners, I would avoid it.
Some disruptive factors can't be avoided while others can, but for most we have the tools to minimize the negative effects.
In the time since the book was published, I have learned more and developed better tools to combat stress's destructive effects and avoid adrenal fatigue and other health problems related to stress.
If you want to avoid the health - damaging effects of soybean, canola, corn and other «vegetable oils», make sure to avoid them as much as you can, and instead opt for truly healthy oils and fats such as extra-virgin olive oil, avocado oil, virgin coconut oil (a healthy source of MCT fats), and grass - fed butter (a great source of healthy CLA fats).
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