Sentences with phrase «axicabtagene ciloleucil»
Dr. Locke participated in the clinical trials that led to US Food and Drug Administration approval of a novel chimeric antigen receptor (CAR) T - cell therapy called axicabtagene ciloleucel.
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Cancer Network: Can you tell us what CAR T - cell therapy is in general and then describe axicabtagene ciloleucel specifically?
Other CAR T - cell therapies approved in 2017 include tisagenlecleucel for the treatment of children and young adults up to 25 years of age with relapsed or refractory B - cell precursor acute lymphoblastic leukemia and axicabtagene ciloleucil (aci - cel; Yescarta) for adults with relapsed or refractory DLBCL.
The FDA has approved the CAR T - cell therapy axicabtagene ciloleucel (Yescarta) for the treatment of large B - cell lymphomas in adults who have failed or relapsed after two or more prior treatments.
City of Hope will be the one of the first authorized centers in the nation to provide axicabtagene ciloleucel, which the U.S. Food and Drug Administration (FDA) announced today is the first approved CAR T therapy for adult patients who have not responded to or who have relapsed after at least two other kinds of treatment.
The FDA granted approval to Yescarta ™ (axicabtagene ciloleucel, Kite / Gilead) for the treatment of adult patients with several types of non-Hogdkin large B cell lymphoma that is refractory or has relapsed after at least two previous systemic treatments.
Other product sales, which include Letairis ® (ambrisentan), Ranexa ® (ranolazine), AmBisome ® (amphotericin B liposome for injection) and Yescarta ® (axicabtagene ciloleucel), were $ 626 million for the first quarter of 2018 compared to $ 536 million for the same period in 2017.