Sentences with word «axon»

For their analyses, the scientists specifically colored the places of origin of axons of so - called pyramidal cells in the hippocampus.

A research team has identified a gene that, upon elimination, could potentially spur regeneration of axons in nerve cells severed by spinal cord injury.

Levin's team suspected those charges slowed or stopped the growth of axons from the newly transplanted eye.

Long, thin fibers called axons extend from neural cells, and the particular geometry of the thalamus, with its many connections, makes it particularly vulnerable to injury.

«A better understanding of the mechanisms involved in axon guidance will offer new possibilities for developing techniques to treat lesions resulting from spinal cord injuries, and possibly even neurodegenerative diseases.»

The out - of - place organs extended information - transmitting nerve fibers known as axons into the animal's brain.

Finally, the CFC has discovered a unique population of glia in proximity to retinal ganglion cell axons as they exit the retina.

In marked contrast, human glial precursor cells and astrocytes generated from these cells by exposure to ciliary neurotrophic factor both failed to promote significant behavioral recovery or similarly robust neuronal survival and support of axon growth at sites of injury.

We're focused on glaucoma and it has to do with a set of very surprising findings in a region that we know is critical for axon loss in glaucoma, which is the optic nerve head.

They found that stimulating ZI GABA neurons with axons extending into the paraventricular thalamus (PVT) prompted immediate binge - like eating, just two to three seconds after stimulation.

Some RGC axons grew all the way back to the brain's visual - processing areas.

For electrical signals to move between nerve cells, or from nerve cells to other cells (such as muscle cells), those signals must travel along axons.

In contrast, mitochondria moving along the nerve axons of normal mice, viewed under the same time - lapse conditions, resembled an aerial shot of a highway.

Misrouting has been attributed to the absence of the directional cues required for normal RGC axon guidance.

When pathologists perform autopsies on people with diffuse axonal injury, they see severed axons with swollen tips, just like what Smith sees in his experiments.

Instead, supportive cells called oligodendrocytes are responsible for making the myelin sheath that wraps around axons.

The study, «Facilitation of axon regeneration by enhancing mitochondrial transport and rescuing energy deficits,» which has been published in The Journal of Cell Biology, suggests potential new strategies to stimulate the regrowth of human neurons damaged by injury or disease.

At a higher level of magnification you can see inside the neurons where little corpuscles stream down the long axons like traffic down a highway.

LKB1 - NUAK1 kinase pathway regulates terminal axon branching through mitochondrial trafficking.

A recent finding in our laboratory led to the novel hypothesis that immune system events involving lymphocytes are necessary for RGC cell death and optic nerve axon loss in glaucoma.

The ZTE AXON Max as mentioned sports a 6 inch AMOLED 2.5 D curved screen supporting 1920 x 1080p (FHD) pixels resolution.

The purpose of this study is to assess the utility of pNF - H, a biomarker released from damaged axons of the spinal cord into the bloodstream, to predict return of function following surgery in dachshunds without pain sensation in their hind limbs due to disc herniation.

Taxt T, Storm - Mathisen J (1984) Uptake of D - aspartate and L - glutamate in excitatory axon terminals in hippocampus: autoradiographic and biochemical comparison with gamma - aminobutyrate and other amino acids in normal rats and in rats with lesions Neuroscience, 11 (1), 79 - 100 PubMed 6143283

In the central nervous system, severing axons causes the entire neuron to die quickly, but why they die has been a mystery.

In contrast, axon bundles spanning the two membranes were clearly nonadherent and would undergo free lateral motion with agitation of the chamber.

Similarly, rat neurons extended axons into the grafted material and cells.

Compressive injury associated with the elevated eye pressures in glaucoma is thought to exert a deleterious effect directly on RGC axons at this site, eventually compromising the normal biological processes required for overall RGC health, and ultimately leading to RGC death.

But DTI imaging had a major glitch: When axons from different tracts intersected and crossed en route to their target, the DTI software got confused and couldn't determine each tract's direction with complete accuracy.

They found that when Axed function was blocked, injured axons not only maintained their integrity but remained capable of transmitting signals within the brain's complex circuitry for weeks.

The tendrils in pink are nerve axons reaching out from a transplanted eye.

Using diffusion tensor imaging (DTI), which can depict axonal fibers, they found a thick cable of what looked like new axons sprouting at the back of the patient's brain.

She is a recognized leader in the field, especially for her use of in vivo imaging methods to study the mechanisms controlling neuronal axon growth.

The study examined animals in their «childhood,» from birth onwards, as this is the critical stage of life in which axons receive their myelin insulation.

«We are the first to demonstrate that a receptor known to convey information from the outside of the cell to the inside of the cell is essential for axon degeneration after injury,» said study co-author Christopher Deppmann, a UVA biology, neuroscience, cell biology and biomedical engineering professor.

Today a rising star in neuroscience at the University of Chicago, Zou made a name for himself by being the first to discover the molecular signals that guide axons longitudinally along the spinal cord, toward or away from the brain.

Planum temporale asymmetries correlate with corpus callosum axon fiber density in chimpanzees (Pan troglodytes).

The experience of pain typically starts in receptors near the skin called nociceptors that transmit information through axon fibres to neurons in the spine, then to the brain.

«Treating axonal degeneration could potentially help a lot of patients because there are so many diseases and conditions where axons are inappropriately lost,» says Aaron DiAntonio, MD, PhD, professor of developmental biology.

Several neurological disorders, including autism and schizophrenia, are thought to be driven in part by the failure of myelin to properly surround axons during development.

«We know that growing axons form fascicles, but we do not know how fascicles form,» says Yoshiho Ikeuchi, a lecturer at the Institute of Industrial Science at the University of Tokyo and senior author of the study.

Also, as much as I would really hope it will not impact AXON awards, I don't see how it could POSSIBLY stay anywhere close to the value it is now.

Consequently, in adulthood, there were not enough mature cells, leaving many axons without insulation.

Organization of myelinated axons by Caspr and Caspr2 requires the cytoskeletal adapter protein 4.1 B.

Previous work by Freeman's lab identified another enzyme, a gene called SARM, which was the first shown to activate a process that causes axons to disintegrate when damaged.

Yi J.J., Barnes A.P., Hand R., Polleux F. and Ehlers M.D. (2010) TGFβ signaling specifies axons during brain development.

It is known that the SMN protein controls RNA processing and is important for axon development, but the details remain enigmatic.

Glutamate indirectly activates the substantia nigra and ventral tegmental area, which contain cells whose axons release dopamine in the hippocampus.

In the central nervous system, the cells responsible for insulating axons are called oligodendrocytes.