Sentences with phrase «axon regeneration in»

His laboratory at Stanford University School of Medicine is developing novel stem cell and nanotherapeutics approaches for ocular repair, studying retinal ganglion cell development, survival and axon regeneration in glaucoma, and investigating the cellular basis for the developmental loss of axon growth ability.

In Aim 2, we will examine whether the rate and pattern of axon regeneration in these knockout mice are affected.

We are further exploring the molecular network in which the Tsc proteins function, and have found that modulation of the growth - promoting mTOR pathway, which is regulated by TSC proteins, can promote axon regeneration in the adult central nervous system.

Not exact matches

But exploring the role of PPM - 2 in controlling DLK - 1 and axon regeneration could be worthwhile — and could have implications in neurodegenerative diseases.»

The study describes how RPM - 1 regulates the activity of a single protein known as DLK - 1, a protein that regulates neuron development and plays an essential role in axon regeneration.

In a study published last summer in PLOS ONE, Lee and his colleagues found that the protein p45 promotes nerve regeneration by preventing the axon sheath (known as myelin) from inhibiting regrowtIn a study published last summer in PLOS ONE, Lee and his colleagues found that the protein p45 promotes nerve regeneration by preventing the axon sheath (known as myelin) from inhibiting regrowtin PLOS ONE, Lee and his colleagues found that the protein p45 promotes nerve regeneration by preventing the axon sheath (known as myelin) from inhibiting regrowth.

The study, «Facilitation of axon regeneration by enhancing mitochondrial transport and rescuing energy deficits,» which has been published in The Journal of Cell Biology, suggests potential new strategies to stimulate the regrowth of human neurons damaged by injury or disease.

«Maybe it's not surprising that a highly evolved central nervous system wound response, such as scar formation, would play a crucial beneficial function in both wound healing and axon regeneration,» he said.

During his doctoral and post-doctoral work under the mentorship of Jeffrey Goldberg, MD, PhD, and Larry Benowitz, PhD, Dr. Trakhtenberg discovered (1) how Set - β and PP2A proteins regulate axon growth; (2) the role of serotonin receptor 2C in neurite growth and processing of visual information; and (3) that inhibiting the transcription factor Klf9 acts synergistically with zinc chelation in stimulating axon regeneration.

Our approach is innovative in that we propose to study a novel group of bioinformatically - predicted factors, which we hypothesize cooperate in controlling RGC axon growth and regeneration.

What his group found is that not only does that promote axon regeneration all the way back down the nerve, but in fact those axons go back to the right areas that they're supposed to get to in the brain — the right brain nuclei — and restore some measures of visual function.

In this study, we will examine whether glial cells and certain proteins secreted from these cells influence axon regeneration and guidance in the optic nerve in adult micIn this study, we will examine whether glial cells and certain proteins secreted from these cells influence axon regeneration and guidance in the optic nerve in adult micin the optic nerve in adult micin adult mice.

Searching the entire genome, a Yale research team has identified a gene that when eliminated can spur regeneration of axons in nerve cells severed by spinal cord injury.

The Yale team found more than 580 different genes that may play a role in regeneration of axons in nerve cells, something that rarely occurs in adult mammals but is of vital interest to scientists hoping to repair injuries to the central nervous system.

The researchers also reported that eliminating one of those genes, Rab27, led to regeneration of axons in the optic nerve or spinal cord of mice.