Sentences with phrase «axonal form»

The proband, a 41 - year - old woman, and her daughter present a severe axonal form of Charcot - Marie - Tooth (CMT) disease.

Not exact matches

First, looking at a study of 185 cases of childhood epilepsy, Wittkowski's team found that mutations in genes that control axonal guidance and calcium signaling — both of which are important early in the developing brain when neurons are forming the appropriate connections — led to increased chances of having the disorder.

Instead, RIPK1 appears to fuel axonal damage across various forms of inherited and acquired forms of ALS.

Looking closer at the transplant recipients, Levin and Blackiston noticed differences in the ways the eyes formed axonal connections.

The findings suggest that RIPK1 may be involved in a range of other neurodegenerative diseases marked by axonal damage, including multiple sclerosis, certain forms of spinal muscular atrophy and even Alzheimer's disease.

Here we identify protein kinase N1 (PKN1) as a novel key player in fine - tuning the balance between axonal outgrowth and presynaptic differentiation in the parallel fiber — forming (PF - forming) cerebellar granule cells (Cgcs).

An intriguing clue to this selectivity is provided by Setola et al., who identify a truncated form of SMN1 that arises from an alternative spliced SMN1 transcript that is preferentially expressed in the axonal projections of developing motor neurons.

Myelin forms an insulating layer around these axons, the purpose of which is to allow electrical impulses to transmit efficiently and rapidly along the axonal pathways.