Sentences with phrase «axons during»

Yi J.J., Barnes A.P., Hand R., Polleux F. and Ehlers M.D. (2010) TGFβ signaling specifies axons during brain development.

Several neurological disorders, including autism and schizophrenia, are thought to be driven in part by the failure of myelin to properly surround axons during development.

Indeed, the rapid remodeling of the axon during local morphogenetic events such as axon elongation, branch formation and elimination and synapse consolidation has an important energetic toll.

Not exact matches

In 2011 researchers found that these waves of electricity cause neurons in the hippocampus, the main brain area involved with memory, to fire backward during sleep, sending an electrical signal from their axons to their own dendrites rather than to other cells.

During brain development, neurons have to connect to each other, which they do by extending their long axons to touch one another.

«Typically, an overproduction of axons and synapses can be found during early puberty, followed by rapid pruning during later puberty, indicating that connections and communication between subcortical and cortical regions are in a highly transitional state during this period.»

Deppmann and his graduate student, Kanchana Gamage, the study's lead author, believe that axons communicate the death message to each other during injury as a leftover activity, «borrowed» from the nervous system's developmental period when axons are overproduced and then improper or unnecessary connections are eliminated by a similar communication between axons.

During development, axons must follow specific paths in the nervous system in order to properly form neural circuits and allow neurons to communicate with one another.

During early development, axons are pruned to ensure normal growth of the nervous system.

During development, these cells migrate with the axons that they will myelinate, and depend on those same axons for appropriate signals to survive and differentiate.

During his doctoral and post-doctoral work under the mentorship of Jeffrey Goldberg, MD, PhD, and Larry Benowitz, PhD, Dr. Trakhtenberg discovered (1) how Set - β and PP2A proteins regulate axon growth; (2) the role of serotonin receptor 2C in neurite growth and processing of visual information; and (3) that inhibiting the transcription factor Klf9 acts synergistically with zinc chelation in stimulating axon regeneration.

We will leverage state - of - the - art bioinformatic and biological approaches for investigating how these factors interact in combination to regulate axon growth during RGC development and test the potential of such factors for regenerating RGC axons in a rodent model of optic nerve injury.

Figure summarizing the three major steps of axon development in the CNS: axon specification during neuronal polarization, axon growth and guidance, axon branching and presynaptic development (Modified from Lewis, Courchet and Polleux, The Journal of Cell Biology, 2013).

When retinal ganglion cell (RGC) axons are injured, before completely degenerating, they exhibit a phase during which their internal «skeletal» structure (normally consisting of a highly organized arrangement of fibers) becomes disorganized.

The new device, which ZTE introduced during this year's IFA trade show in Berlin, incorporates many of the award - winning features consumers» value from the AXON 7, all within a 5.2 - inch screen size.