Suspecting that the clustering of nerves in the striatum may somehow relate to their function, Professor Graybiel later showed (in monkeys) that neurons in the sensory cortex, where sensation is perceived, project
axons into the striatum.
This electrochemical charge races up
their axons into other layers of the cortex and is ultimately transmitted to other regions of the brain.
Similarly, rat neurons extended
axons into the grafted material and cells.
The out - of - place organs extended information - transmitting nerve fibers known as
axons into the animal's brain.
The 2 - millimeter organoids survived for at least two months, Chen said in an interview, and showed «extensive» growth of human
axons into the rat brain.
Not exact matches
Neural stem cells differentiate
into three different cell types: neurons (purple), oligodendrocytes (red), which produce
axon insulation, and astrocytes (green), which also support neurons.
Concentrations of photographic grains were observed only over regions of preterminal autonomic
axons containing granulated vesicles, thereby directly demonstrating uptake of norepinephrine
into these
axons and strongly suggesting that their granulated vesicles contain norepinephrine.
A few microscopic techniques can focus light deep
into the intact brains of dead animals to study its structure without damaging the
axons, but much of this light is scattered away by the fatty lipid membranes that surround individual cells, making the technique less than perfect.
Unexpectedly, the team discovered a thick band of microtubules, a component of the cell's cytoskeleton, that extended from the
axon of the neuron
into the synaptic terminal and then looped around the interior periphery of the terminal.
Rossoll and his colleagues showed that the SMN protein is acting like a «matchmaker» for messenger RNA that needs partners to transport it
into the cell
axon.
Axons can be very long and relatively remote from the central portion of the cell, which houses the nucleus where DNA is transcribed
into messenger RNA that can then be converted
into proteins.
The main body of the neuron conveys those pulses to an outgoing arm, or
axon, which splits
into numerous branches, each of which nearly touches other neurons.
Axons that are supposed to grow
into the muscle on the eye's inner edge may end up on the outer edge instead.
The third, a powerful growth factor called GDNF, was later injected
into sciatic nerves to lure the
axons to reach out to peripheral muscles.
When they tracked the cells»
axons from the eye
into the brain, they saw that many of them terminated in the lateral geniculate nucleus (LGN), the first relay station in the brain for visual information.
In July, however, researchers reported in the journal Neuron that the stringy extensions, or
axons, of mRGCs extend
into parts of the mouse brain involved in conscious vision, not just the parts of the brain that control unconscious responses to light.
The
axons of grid cells project
into the hippocampus and it has been assumed that without this relay of information from the entorhinal cortex to the hippocampus, place cells would be unable to develop.
«The enormous outgrowth of
axons to many regions of the spinal cord and even deeply
into the brain raises questions of possible harmful side effects if
axons are mistargeted.
The cells» dendrites form the feathery outer fringe, and the
axons gathered in the middle dive
into the depths of the cerebellum to send signals within.
In these mice, 90 per cent of the
axons in the SC had extended
into the wrong areas.
To connect with other neurons
into circuits, neurons grow long branch - like structures called
axons and dendrites.
This slower type of
axon death may happen when someone suffers mild but repeated brain injuries, exactly the kind that football players experience as they crash
into each other in game after game.
«Most previous scaffolds have supported
axon growth
into the scaffold but not out again.
Viral DNA that jumped
into our ancestors» genes millions of years ago may contribute to the chewed up
axons (blue cylinders) that cause multiple sclerosis.
«Within 3 weeks after expression of the NeuroD1 protein, we saw in the microscope that human glial cells were reinventing themselves: they changed their shape from flat sheet - like glial cells
into normal - looking neurons with
axon and dendritic branches,» Chen said.
They found that stimulating ZI GABA neurons with
axons extending
into the paraventricular thalamus (PVT) prompted immediate binge - like eating, just two to three seconds after stimulation.
Infection happens in peripheral tissues, then the virus particles enter
axons and zoom
into the distant cell nucleus, where the viral genetic information can become latent, sleeping for days or even years.
Injected botulinum toxin is taken up in
axons and reaches the cell body, shown in green, before being transported
into different neurons, shown in red.
Theses landmarks are then recognized by growth cones at the tip of
axons — the projections that grow out from the retinal neurons and
into the brain.
mRNAs and Protein Synthetic Machinery Localize
into Regenerating Spinal Cord
Axons When They Are Provided a Substrate That Supports Growth.
In theory, a transplanted organ could hack
into its host's nervous system by growing
axons that connect with the host's cells.
Promoting directional
axon growth from neural progenitors grafted
into the injured spinal cord.
For this we inject themselves
into the vitreous,
into the center of the eye, and what we're finding is that a subset of the injected retinal ganglion cells can go
into the retina, the green cells are the donor cells, they extend all of their
axons and dendrites.
Here the
axons going down the optic nerve, across the optic chiasm, and
into the expected targets in the brain: the lateral geniculate and the superior colliculus.
GenSight's treatment is for people with damaged photoreceptor cells but intact ganglion cells; it inserts the gene
into the ganglion cells, whose
axons form the basis of the optic nerve.
And they tested the technology on a tiny slice of an adult mouse's neocortex, gaining new insights
into the complex relationship between
axons (nerve fibers) and dendrites (branches on neurons that act kind of like electric input sockets).
These range from visual stimulation experiments that allow us to tap
into the specific sets of retinal ganglion cells that are most vulnerable early in the disease, to the evolution of new imaging techniques, largely thanks to Alf Dubra and Vivek Srinivasan's work in those areas, and the ability to image retinal ganglion cells and their component parts like their
axons which degenerate very early in glaucoma.
Right now all therapy for glaucoma is directed at lowering eye pressure, but the idea that we could develop therapies and test them in people that really target the retinal ganglion cells and the
axon fibers going
into the optic nerve — that, I think, is the most exciting new frontier for the premise of restoring vision and protecting vision in glaucoma.
Among the classics is the squid, which made its way
into the history of science on account of the «giant
axon» — a millimeter - wide neuron that runs down the length of each of its tentacles.
Dr. Olby wants to restore the myelin sheath to these surviving
axons by taking fat cells from the patient and turning them
into stem cells that can be combined with nerve cells and injected
into the site of the damage, regrowing the sheath.
The purpose of this study is to assess the utility of pNF - H, a biomarker released from damaged
axons of the spinal cord
into the bloodstream, to predict return of function following surgery in dachshunds without pain sensation in their hind limbs due to disc herniation.
A research team led by Michal Schwartz of Israel's Weizmann Institute of Science grew these immune cells in a laboratory and implanted them
into rats, and the transplants of the cells caused the
axons to regenerate.
And, as you can see, it is also a mere
axon or dendrite away from an incursion
into law itself: