Phages identify and grab bacteria using proteins on their leglike tail fibers, which form a strong bond with compounds on
the bacterial cell surface.
Not exact matches
-- Drinking water fountain spigots had the highest amount of bacteria on the tested
surfaces — 2.7 million
bacterial cells per square inch.
King hypothesizes that proteins that the single -
celled ancestors of animals used to interact with the extracellular environment — to capture
bacterial prey by binding to their
cell surface and to detect chemical signals — were later repurposed to enable
cells to stick to and talk to each other.
The researchers also found that these peptides can destroy certain biofilms, which are thin layers of
bacterial cells that form on
surfaces.
This research is the first to show that the accumulation and
bacterial degradation of skin squames (
cells that peel off from the skin
surface) in air - cooling units is positively correlated to the complaints of urine - like smell in air - conditioned areas.
The researchers assume that this is the signal that sparks off the response: The
bacterial cell now boosts the synthesis of a second messenger, which in turn stimulates the production of an adhesin that firmly anchors the bacteria on the
surface within a few seconds.
Their results showed it to be effective in killing
bacterial cells on contact, severely disrupting the ability of biofilms to grow on its
surface.
They also showed that the cephalosporinases are exported out of the
bacterial cells, attached to the
surface of special packages called outer membrane vesicles (OMVs).
Research groups in Munich, Essen, and Brussels have now detected a highly specific and exceptionally strong variant of this adhesion, in which the
bacterial surface molecule HopQ binds itself to so - called «Carcinoembryonic Antigen - Related
Cell Adhesion Molecules,» or CEACAMs for short, inside the stomach.
Electron microscopy of the inner and outer
surfaces of
bacterial cells gives some clues, and crystallography — a process that involves stacking purified proteins into crystals so that their three - dimensional characteristics can be measured — provides others.
Zooming in on the
surface of growing bacteria, they detected vesicles that were just budding off the
bacterial cell, confirming that GBS produces MVs.
The PATR was shown to be integral in the transport of the virulence factors to the
surface of the
bacterial cell, where they need to be to function as disease - causing agents.
For example, Dr. Shiloh said, preventing Mtb from attaching to receptors on the M -
cell surface — such as by vaccinating against a
bacterial protein — could block the bacteria's entry, infection, and spread to other organs.
«This is the first time that we have been able to actually look at how the components of a
bacterial cell membrane are able to interact with different substances, and understand how differences in metal and mineral interactions can occur on the
surface of a
cell.
«It appears that one or more of these proteins, either within the
bacterial cell envelope or on its
surface, are essential to its growth and survival.
The research team found that Alphamers not only bind strep and recruit anti-Gal antibodies to the
bacterial surface, they also helps human immune
cells engulf and kill the Alphamer - coated bacteria.
Efflux pumps are
surface proteins that prevent antimicrobial drugs from getting a foothold in a
bacterial cell by identifying and pumping them out of the
cell.
The awards span the broad mission of the NIH and include groundbreaking research, such as engineering immune
cells producing drugs at the site of diseased tissue; developing a sensor to rapidly detect antibiotic resistance of a
bacterial infection; understanding how certain parasites evade host detection by continually changing their
surface proteins; and developing implants that run off the electricity generated from the motion of a beating the heart.
«Using proteins that are found on the
surface of
bacterial cells as the basis for vaccination may lack efficacy because of the variability of the exact protein structure,» says Mobley.
The
surface roughness of the material, induced by the introduction of graphene, causes
bacterial walls to be burst while simultaneously allowing the heart
cells to multiply and grow.
Engineering the gram - positive
cell surface for construction of
bacterial vaccine vectors.
It uses a spoon - like device called a tongue cleaner (although you could also simply use a spoon) to scrape the overnight accumulation of
bacterial build - up, food debris, fungi, and dead
cells from the
surface of the tongue.