Sentences with phrase «bacterial genomes as»

We will perform ultra-deep sequencing of your microbiome sample aimed at generating as many individual bacterial genomes as possible (we can't tell you how because the details of the technique are still under wraps prior to publication).

Not exact matches

Together, our collective guts have just under 3.3 million bacterial genes, more than 150 times as many as reside in our own genomes.

Overlapping «cassettes» of 5 to 7 kilobases (kb), assembled from chemically synthesized oligonucleotides, were joined by in vitro recombination to produce intermediate assemblies of approximately 24 kb, 72 kb («1/8 genome»), and 144 kb («1/4 genome»), which were all cloned as bacterial artificial chromosomes in Escherichia coli.

Bacterial genomes isolated after growth in yeast are likely to be susceptible to the restriction - modification system (s) of the recipient cell, as well as their own.

Bacterial genomes are notoriously difficult to modify, and using transfer into yeast as an intermediate step allows scientists to use a much wider range of genetic tools for tweaking the genome.

In 12 biopsies of his remarkably well - preserved gut tissue (and stomach contents), they were able to isolate enough bacterial DNA to sequence the genome of H. pylori to relatively high resolution, as they report online today in Science.

Made into a permanent programme in 2009, it set out to sequence the genomes of potential bioterror agents, explore new drug technologies and develop «broad - spectrum» therapies that would work against multiple bacterial and viral pathogens — especially haemorrhagic fever viruses such as Ebola and Marburg.

As part of the international effort to sequence the 17 — billion — base - pair hexaploid bread wheat genome (2n = 6x = 42 chromosomes), we constructed a bacterial artificial chromosome (BAC)-- based integrated physical map of the largest chromosome, 3B, that alone is 995 megabases.

As reported in tomorrow's issue of Science *, the genome of this laboratory workhorse and common pathogen is 4.6 million base pairs long, making it the largest bacterial genome sequenced to date.

As a step toward propagation of synthetic genomes, we completely replaced the genome of a bacterial cell with one from another species by transplanting a whole genome as naked DNAs a step toward propagation of synthetic genomes, we completely replaced the genome of a bacterial cell with one from another species by transplanting a whole genome as naked DNas naked DNA.

As a result, the CRISPR locus of the bacterial genome accumulates a chronological record of the bacterial viruses that it and its ancestors have survived.

Researchers have already constructed functioning viral and bacterial genomes, and the yeast genome project, known as Sc2.0, aims to have all 16 chromosomes — roughly 10 million base pairs — assembled by the end of next year.

The bacterial genomes come from species that challenge the technical performance of sequencing methods and have been determined by the Food and Drug Administration (link is external)(FDA) to have significant relevance to the research of public health issues such as food contamination, antibiotic resistance and hospital - acquired infections.

Sequencing the genome allowed researchers to identify the gene for lysin, an enzyme that the virus uses to kill bacterial cells, that has potential use as an antibiotic or disinfecting agent.

During their coexistence, the bacterium was further and further integrated as a power plant into the cell, which was evident in the fact that the construction plans of the power plant were increasingly transferred into the host cell from the bacterial genome.

The study results were very surprising: For most of these clinical measures, the association with bacterial genomes was at least as strong, and in some cases stronger, than the association with the host's human genome.

I will review recent advances in the use of nanopore sequencing for clinical microbiology and human genetics, including our collaborations on viral and bacterial diagnostic sequencing, real - time surveillance, direct RNA and human whole - genome sequencing, and discuss the opportunities and barriers around moving to sequencing as a routine test in the clinic.

His research interest focuses on 1) development and application of TALEN and CRISPR technologies for targeted genome editing in plant species, and 2) molecular mechanism of plant / microbe interactions and crop disease resistance engineering by using the bacterial blight of rice as a model.

Strains from the Olive (Olea europaea L.) Rhizosphere as Effective Biocontrol Agents against Verticillium dahliae: From the Host Roots to the Bacterial Genomes — Carmen Gómez - Lama Cabanás — Frontiers in Microbiology

The research, which was funded as part of a collaboration with the University of Oxford, involved professor Peter Andrew from the University of Leicester's Department of Infection, Immunity and Inflammation and professor Chris Bayliss from the University of Leicester's Department of Genetics and Genome Biology, the hepatobiliary and pancreatic surgeon Ashley Dennison from Leicester's Hospitals, the immunologist Luisa Martinez - Pomares from the University of Nottingham and the expert in bacterial pathogenesis Richard Moxon from the University of Oxford.

As of September 1998, we have identified the map positions of bacterial clones covering approximately 860 Mb for sequencing and completed > 98 Mb (approximately 3.3 %) of the human genome sequence.

As both bacterial and viral genomes were detected in the present brain specimens, we examined host genes known to participate in responses to infections.