CRISPR is a technology based on
a bacterial immune defense system which uses Cas9, a nuclease, to cut up foreign genetic material (e.g., viral RNA).
Genomic engineering as a promising cancer therapeutic approach has experienced a tremendous surge since the discovery of the adaptive
bacterial immune defense system «CRISPR» and its potential as a gene editing tool over a decade ago.
Not exact matches
At the first hint of a viral or
bacterial invasion, the
immune system launches an orchestrated front - line
defense.
CRISPRs are
bacterial immune systems that contain many
defense enzymes such as the Cas9 «molecular scissors,» which scientists including Hsu have engineered as a powerful DNA - targeting gene - editing tool.
The results, revealing new examples of heritable
bacterial species — including those related to diet preference, metabolism, and
immune defense — appear May 11 in Cell Host & Microbe's special issue on the «Genetics and Epigenetics of Host - Microbe Interactions.»
They basically store a picture of the virus in their back pocket so that they'd recognize the bad guy if he were to ever show up again — a remarkable
defense mechanism of the
bacterial immune system.
5/24/2007 How Plague - Causing Bacteria Disarm Host
Defense Effector proteins are the bad guys that help
bacterial pathogens do their job of infecting the host by crippling the body's
immune system.
The CAMP gene itself is also the subject of much study, as it has been shown to play a key role in the «innate»
immune system, the body's ability to fight
bacterial infection and the 1st line of
defense.
Normally, there are patches of
immune cells all along the gastrointestinal tract, because of the gut's need for a good first - line
defense against viral and
bacterial invaders.