Now, the Laboratory
of Malaria Immunology Team at the Immunology Frontier Research Center (IFReC), Osaka University, headed by Professor Cevayir COBAN, have used mouse malaria models to show that robust immune activation and invasion
of parasite by - products into the bone marrow during and after malaria infection leads to an adverse
balance in bone homeostasis - a process usually tightly controlled - by bone forming
osteoblasts and bone resorbing osteoclasts.