Sentences with phrase «base pair deletion»

Results: We confirmed the Gallus Gallus v5 consensus except for two insertions of 5 and 1 base pair within the chIFITM3 and B4GALNT4 genes, respectively, and a single base pair deletion within the B4GALNT4 gene.

We have identified a mouse containing a single base pair deletion in the Crb1 gene.

Aberrant splicing was due to a 5 base pair deletion at the branch point in intron 7.

Use of this alternative splice site yields a transcript with an in - frame 21 base pair deletion that deletes 7 amino acids from the translated protein.

The importance of CCR5 for HIV - 1 pathogenesis is shown by the fact that individuals who are homozygous for an inactivating 32 base pair deletion in ccr5 (ccr5Δ32) are highly resistant to HIV infection [2], [3], while heterozygotes typically live longer after HIV infection due to reduced CCR5 expression levels [4], [5].

Not exact matches

Somewhere along the way, certain molecular changes, including a deletion of 29 base pairs from the original virus, allowed SARS to infect and replicate in human cells.

And in January 2009 another Nature Genetics paper found an association between high body mass index and a 45,000 base - pair deletion in a gene called NEGR1, which affects neuronal growth in the hypothalamus, a brain region that regulates hunger and metabolism.

A Nature Genetics study from August 2008 found a link between Crohn's disease and a 20,000 base - pair deletion in a region upstream of a gene called IRGM, which is involved in fighting invasive bacteria.

The scientists also found tens of thousands of new structural variants, such as deletions or insertions of DNA, that are likely to be more important than the smaller single base pair differences that were cataloged before.

We next examined the specific base - pair (bp) insertions and deletions (indels) created during the CRISPR / Cas9 editing process in the clones using the Guide - it Indel Identification Kit.

The statement clarifies that this means the body will not regulate plants that undergo a variety of genetic changes, including genetic deletions, single base pair substitutions, or insertions from compatible plant relatives that could be generated through traditional plant breeding.

Forms of variation include single DNA base pair alterations, duplications or deletions of genes or sets of genes, and translocations, a chromosomal rearrangement in which a segment of genetic material from one chromosome becomes heritably linked to another chromosome.

In addition to the large CNV mutations they had spotted earlier, they also found de novo changes in single base pairs of DNA — known as single - nucleotide variants (SNVs)-- and small de novo insertions or deletions in chromosomes, all of which made the picture even more complex.

Mutations have recently been associated with both disorders; a 1 - base pair insertional mutation in exon 1 of COL9A3 is associated with DRD1 and a 1,267 - bp deletion in the 5» end of COL9A2 co segregates with DRD2.