Sentences with phrase «base pair variant»
«What a pleasant surprise to learn that someone's paying attention to something other than the 48 - base pair variant,» he says.
http://www.genomenewsnetwork.org/ Not exact matches
Their 2006 map identified CNVs only down to 20,000 base pairs; now they are finishing a revised map that includes variants as short as 500 base pairs.
The scientists also found tens of thousands of new structural variants, such as deletions or insertions of DNA, that are likely to be more important than the smaller single base pair differences that were cataloged before.
The trait most likely developed 4800 to 6600 years ago from an earlier variant differing at just two base pairs that these groups got from intermixing with tribes migrating from the Asian Steppes, the team reported here last week at the annual meeting of the American Society of Human Genetics.
Mark Chaisson, a postdoctoral fellow in Eichler's lab and lead author on the study, developed the method that made it possible to detect structural variants at the base pair resolution using this data.
Even more astonishing are the 6 + million coding variants: depending on how you define the exome, that's about one variant every 5 or 6 base pairs in coding regions.
Roughly speaking, that's one variant for every 20.5 base pairs in the human genome.
They took the 10 T2D GWAS loci with the strongest support in their study, and looked for low - frequency missense variants within 2.5 million base pairs of the common index SNV.
In addition to the large CNV mutations they had spotted earlier, they also found de novo changes in single base pairs of DNA — known as single - nucleotide variants (SNVs)-- and small de novo insertions or deletions in chromosomes, all of which made the picture even more complex.
Petrol power comes from a 1.6 - litre VTVT unit that produces 123 PS, paired to a 6 - speed manual gearbox and will power the base variants.
The Q3 S is the base variant of Audi's entry - level SUV with skimped down features and is currently available only with a diesel engine paired to a manual transmission that sends power to the front wheels.
Specialist coachbuilder Baur wasted little time in developing a pair of soft - top variants based on the BMW 02 range which were produced until 1975.
Toyota has also added a new base variant on the 2015 Camry that uses a 2.0 - litre 4 - cylinder petrol mill belting out 150 HP, paired to a 6 - speed automatic transmission.
Despite the fact that the phone will have up to four different variants, the entire collection will be based on the new Qualcomm Snapdragon 660 SoC paired with either 3 GB RAM and 32 GB storage or 4 GB RAM and 64 GB of storage.
A variant of the iPad Pro will be available with built - in LTE, although when paired with 128 GB of storage the price of this tablet could approach a base model MacBook.