Sentences with phrase «base pairs into»

The recently launched Gemcode system adds a new dimension to short - read DNA sequencing, by enabling the ordering of millions of barcoded short sequence reads of 150 base pairs into long continuous DNA molecules of hundreds of thousands of base pairs in size.

The result was a base editor, called ABE, that could switch A-T base pairs into G - C pairs in about 50 percent of human cells tested.

With us, ultimately the reason we failed is because we couldn't get 20,000 base pairs into a plant.»

Not exact matches

So why not look into the growth strategy tips of a pair of Stanford MBAs whose startup has expanded its customer base nearly 200 percent a year in the last two - and - a-half years?

DNA has been around for billions of years, but demonstrations of DNA as a usable storage technology began in 1986 when MIT researcher Joe Davis encoded a simple binary image into 28 base pairs of DNA.

On the Help Scout homepage, you'll see we've a rotating section that pairs testimonials, company logos, and our growing customer base into a single form of social proof.

They built up the synthetic genome from 1078 units of approximately 1000 base pairs, assembling them into larger and larger units by a factor of ten each time, until they created the complete genome of about 1.08 million base pairs after three such stages.

Fats in meat - based broths pair well with vinegar since it helps to draw out all those valuable minerals in the bones into the broth.

Like potatoes, corn often gets put into the «plants with no redeeming qualities» category, but paired with protein - rich veggies and legumes, it can nicely round out a protein - packed plant - based dish.

It's this terrain, paired with the close proximity to major metro areas, base area facilities, experience hosting large - scale events and shared history with the rise of obstacle racing, that all factored into Tough Mudder's desire to return for 2017.

The President and his Vice are a very good pair, they work well together despite their religion but the problem will come from the followers, and they are the ones who brought the party into power so the party should work hard in teaching their followers to be tolerant towards each other no matter their tribal or religious differences or else if the NDC is a able to reorganize themselves and choose a better running mate, there will be a run off and that is where the NDC will take the lead» The Eagle Prophet told Owusu Agyemang on Accra - based Hot 93.9 FM

House Republican leaders on Capitol Hill said they were launching two new investigations into Hillary Clinton, keeping alive a pair of storylines that have fueled anger with the party base.

They work out of a pair of canalfront houses whose interiors have been transformed over the years into mission control for the world's only surviving full - fledged sea base, called Aquarius.

But with the RNAs that condense into the same droplet, their complementary sequences are really exposed, so they can find each other and base pair to make a higher - order interaction,» Gladfelter says.

The genome proved to be more than a million base pairs longer than the TIGR team expected, and to be divided into one large and one small chromosome.

Communities were matched into pairs based on sociodemographic, cultural and infrastructure characteristics, with one community randomly assigned to the intervention and one serving as a control for comparison.

But genes in other regions are so close together they overlap: the cluster of 75 genes which determines tissue type and plays a part in controlling our immune responses is packed into only 4 million base pairs.

It recognizes the specific DNA sequence by inserting a pair of α - helices into grooves of the DNA helix and sensing functional groups on DNA base - pair edges.

The A. tumefaciens plasmids broke into the plant cell and penetrated its DNA, inserting up to 25,000 base pairs of its own.

They took one person's DNA (the molecule that contains all genes), chopped it up into little pieces and determined the sequence of base pairs in each piece.

When Ghadiri poured tPNA molecules into a soup of DNA bits, the tPNA base pairs reshuffled until they matched the sequence of a DNA strand.

When data are fed into the network, setting off a cascade of firing activity, the algorithm determines based on the firing patterns whether to increase or decrease the weight of the connection, or synapse, between each pair of neurons.

TerraLeaf is working on using chlorophyllin — the chlorophyll from a plant turned into a salt by adding sodium ions and copper — paired with an electrically conducting polymer to form a membrane that can pull CO2 (or other greenhouse gases) from air and form carbon - based chemicals, and potentially even fuels.

Molecular recognition (base pairing, i.e., A binds to T and G binds to C) directs the DNA to self - assemble into a specific structure as programed by the staple strand sequences.

In 2014, the scientists engineered Escherichia coli bacteria (pictured) to incorporate an additional pair of bases — X and Y — into their DNA.

So in the new study the researchers slipped the «alien» pair of bases into bacterial genes that also contained traditional bases.

We report the design, synthesis, and assembly of the 1.08 — mega — base pair Mycoplasma mycoides JCVI - syn 1.0 genome starting from digitized genome sequence information and its transplantation into a M. capricolum recipient cell to create new M. mycoides cells that are controlled only by the synthetic chromosome.

Using enzymes, the genome is cut into random fragments of around 200 base pairs each.

After isolating RNA from various human tissues, the researchers copy it into DNA, from which they cut out a kind of genetic bar code of 10 to 20 base pairs.

Vtor A. P. Martins dos Santos of the German Research Center for Biotechnology and his colleagues broke the marine organism's genome into more than 3 million base pairs and then pieced them together into a complete genetic map.

Then they smashed the DNA into smaller fragments, sequenced 1.05 billion base pairs, and used computer models to reconstruct partial genomes of different species.

Working with French composer Richard Krüll, the pair turned the complete nucleotide sequences of several microbe genes into compositions based on DNA bases: A (adenosine), C (cytosine), G (guanine), and Thymine (which they have translated to «Re,» or D).

(The team doesn't yet understand why, because the changed base pair lies in a region that is not translated into RNA and is not usually involved in switching genes on and off.)

(Base pairs are the two chemicals that bond into a rung on the DNA ladder)

After that, the researchers back - translate the amino acid sequence into a genetic sequence, buy the DNA base pairs to build the gene spelled out by that sequence, and then turn the gene loose in bacteria or yeast that have been programmed to manufacture the protein.

FATE MAPPING WITH CRISPR: Thanks to a new tool called GESTALT, researchers can now introduce a 300 - base - pair lineage barcode into cells and, using the CRISPR - Cas9 system, allow edits to accumulate as those cells divide.

Three human cornea pairs (donor ages 30 - 37 years), stored in Optisol, were labeled by chemifluorescence to show incorporation of BrdU into new DNA using a commercial procedure (Hoffman - La Roche, Nutley NJ) as based on the work of Elwart and Dormer [21].

Genomic DNA was sheared into 250 — 350 base - pair fragments by focused ultrasonication (Covaris Adaptive Focused Acoustics technology (AFA Inc., Woburn, USA), and amplification - free Illumina libraries were prepared16.

A complex technical challenge To put the huge size of the bread wheat genome into context, its constituent number of paired DNA bases, or nucleotides, totals 17,000,000,000 base - pairs (17 Gb).

In the next set of experiments, they engineered DNA bubbles into the DNA that varied between 3 and 12 base pairs and tested what size bubble would allow transcription to proceed in the absence of TFIIH, the basal or general transcription factor they implicated in forcing these DNA bubbles open.

The polyT repeat (rs10524523) genotypes were placed into categories modeled after those reported by Roses et al12: short (246 - 267 base pair [bp]-RRB-, long (268 - 279 bp), and very long (280 - 289 bp)(Supplemental Figure 2; http://neuroscienceresearch.wustl.edu/Pages/cruchaga2011.aspx).

Base calling was performed with the machine learning algorithm Ibis [63] and overlapping read pairs obtained from paired - end sequencing runs were merged into single sequences.

We have gone from sequencing small fragments of DNA to full mitochondrial genomes (17,000 base pairs of genetic code), and then in the last three years the field exploded into the realm of complete nuclear genomes.

In a previous study, we showed that genomic rearrangements of up to one million base pairs can be generated by direct injection of CRISPR / Cas9 reagents into mouse zygotes.

The device runs DNA through the voltage, which changes the signals, and converts the tiny changes into the base pairs, and then into the data analyzed by a computer.

However, it is practically difficult to perform the rescue experiments in the organoid culture system because the lentivirus transfection is required for the gene transduction into the primary stem / progenitor cells and the APC gene (> 8.5 k base pairs) is too large to be cloned into the lentivirus.

You might remember I talked a bit about getting into exercising a little more and especially walking a lot more back in August: I have been after investing in a nice and comfy pair of sneakers ever since, looking in particular for some shoes I could actually also wear on a daily basis (so yes, I wanted them to be cute!).

Before we jump too far into spring, I have to touch base on how important having a good pair of boots is.

It would pair with anything, it would be a suitable base for any glitter, and would work into any nail art look you could imagine.

By following five Atlanta - based couples, the film wants fervently to incorporate all its character's diverse fluff into one sitting, but such hopes are subverted to an emptily - flat experiment that pairs audiences with familiar faces acting out a weak script, while the experimenters stand back and pray that the audience doesn't notice just in fact how hollow it all really is.