Sentences with phrase «based human phenotype»
Dartmouth researchers developed a new biological pathway - based computational model, called the Pathway - based Human Phenotype Network (PHPN), to identify underlying genetic connections between different diseases as reported in BioDataMining this week.
https://www.sciencedaily.com/ Not exact matches
Using advances in genomic sequencing, the human microbiome, proteomics, informatics, computing, and cell therapy technologies, HLI is building the world's most comprehensive database of human genotypes and phenotypes as a basis for a variety of commercialization opportunities to help solve aging related disease and human biological decline.
The concept of race (based on phenotype — such as the amount of melanin in the skin — this is what Chad means when he uses the word) has largely been discredited and discarded due to our recent understanding of the human genome.
A total of 22 mouse mutant lines can be characterised through a broad based primary phenotyping pipeline in all the major adult organ systems and most areas of major human disease.
«This agreement is a part of deCODE's ongoing strategy to unleash the value of human genetics,» said Kari Stefansson, founder and CEO of deCODE, «our research platform allows us to understand the genetic basis of disease and modifiers of clinical phenotypes in actual patient populations; by doing so, we can rapidly move from targets to patient stratification and from there to companion diagnostics.»
Using advances in genomic sequencing, the human microbiome, proteomics, informatics, computing, and cell therapy technologies, HLI is building the world's most comprehensive database of human genotypes and phenotypes as a basis for a variety of commercialization opportunities to help solve aging related disease and human biological decline.
Mouse mutant lines can be tested through a broad based primary phenotyping pipeline in all the major adult organ systems and most areas of major human disease.
Her first research internship was at the Comparative Genomics group of the Radboud University where she, under supervision of Martijn Huynen, made a computational tool that prioritizes genes based on human phenotypes.
Ageing research and more generally the study of the functional basis of human diseases profit enormously from the large - scale approaches and resources in mouse functional genomics: systematic targeted mutation of the mouse genome, systemic phenotyping in mouse clinics, and the archiving and distribution of the mouse resources in public repositories.
Test each mutant mouse line (4,000 mouse lines in the first 5 years, and ultimately up to 20,000) through a broad based primary phenotyping pipeline in all the major adult organ systems and most areas of major human diseases.Through this activity and employing data annotation tools, systematically aim to discover and ascribe biological function to each gene, driving new ideas and underpinning future research into biological systems.