Based at the Cancer Research Institute in New York, Old is the director of the Cancer Vaccine Collaborative, an international program dedicated to fighting cancer from the inside out.
Professor John Griffiths, co-lead researcher
based at the Cancer Research UK Cambridge Institute, said: «The revelation that different types of brain tumours appear to be using similar tricks to survive was startling.
Dr Madhu Basetti, co-lead researcher also
based at the Cancer Research UK Cambridge Institute, said: «Our study is the first to use this approach to compare how different cancers use and produce energy, and look for similarities.
Not exact matches
PICI (pronounced «pie - sea»), as it's called by its member scientists, is doing something unprecedented in academic medicine: combining and coordinating the efforts of six of the top
cancer immunology centers in the country — MD Anderson Cancer Center, Memorial Sloan Kettering, Penn Medicine, Stanford, UCLA, and UCSF — in order to greatly expand and, more important, to accelerate our understanding of why some immune - based treatments work miraculously in some patients and not at all in o
cancer immunology centers in the country — MD Anderson
Cancer Center, Memorial Sloan Kettering, Penn Medicine, Stanford, UCLA, and UCSF — in order to greatly expand and, more important, to accelerate our understanding of why some immune - based treatments work miraculously in some patients and not at all in o
Cancer Center, Memorial Sloan Kettering, Penn Medicine, Stanford, UCLA, and UCSF — in order to greatly expand and, more important, to accelerate our understanding of why some immune -
based treatments work miraculously in some patients and not
at all in others.
• Aileron Therapeutics, a
cancer treatment biotech
based out of Cambridge, Mass., said it plans to offer 3.75 million shares between $ 15 to $ 17, raising about $ 60 million
at the offering's midpoint — about $ 25 million of which will be bought by insiders.
Merck — Merck was upgraded to «buy» from «neutral»
at Goldman Sachs and added to Goldman's «Conviction Buy» list,
based on Merck's success with its
cancer drug Keytruda.
The Pershing Square Sohn Prize for Young Investigators in
Cancer Research will provide young New York -
based scientists the freedom to take risks and pursue their boldest research
at a stage when traditional funding is lacking.
Parker Institute affiliated co-authors on the paper include Dr. Okada and Carl June, M.D., a Parker Institute director
based at the Abramson
Cancer Center of the University of Pennsylvania.
Prior to joining Oberon, David was Chief Financial Officer and Treasurer
at VolitionRx (NYSE MKT: VNRX), a multi-national medical diagnostics company developing simple blood -
based tests to accurately diagnose a range of
cancers.
The FDA approved a Lutetium - 177
based cancer therapy called Lutathera for the treatment of neuroendocrine tumors earlier this year, after Novartis snapped up the developer, Advanced Accelerator,
at a premium.
Looking
at sixty - seven recent drug discovery projects
based on preclinical
cancer biology research, they found that in more than 75 percent of cases the published data did not match up with their in - house attempts to replicate.
The win / win benefits to not only the environment but also health care — with plant -
based diets known to reduce heart disease, diabetes, several types of
cancer, and obesity (currently
at a shocking 23 per cent, with 60 per cent of Canadians overweight)-- make this negligence incomprehensible.»
Melanie Young (New York, NY)-- Chief Connector and Creative Strategist
at The Connected Table, a New York -
based public relations and events business, Melanie is a speaker and author of Melanie Young — Getting Things Off My Chest: A Survivor's Guide to Staying Fearless and Fabulous in the Face of Breast
Cancer, which provides tips for women on how to manage their diagnosis and stay focused and in charge of their health.
In an accompanying editorial, Theodore Slotkin, a professor of pharmacology and
cancer biology
at the Duke University School of Medicine in Durham, North Carolina, writes that it's undeniable that smoking while pregnant contributes to later behavior problems in children,
based on the new study and past research.
Children who are exposed to second - hand smoke on a regular
basis are
at greater risk for developing respiratory illnesses, asthma and
cancer.
Lacewell is returning to the administration after a stint as the executive director of
Cancer Breakthroughs 2020
at the California -
based Chan Soon - Shiong NantHealth Foundation.
Cancer treatment guidelines produced by the US National Comprehensive
Cancer Network (NCCN) are often
based on low quality evidence or no evidence
at all, finds a study published by The BMJ today.
Based on the evolutionary idea that targeted epigenetic stochasticity can improve adaptation, these observations could explain how
cancer cells are good
at evading chemotherapy treatments and spreading from one part of the body to another, he adds.
«Our discovery of these mutations is a first step in developing a genetics -
based system for classifying endometriosis so that clinicians can sort out which forms of the disorder may need more aggressive treatment and which may not,» says Ie - Ming Shih, M.D., Ph.D., the Richard W. TeLinde Distinguished Professor in the Department of Gynecology & Obstetrics
at the Johns Hopkins University School of Medicine and co-director of the Breast and Ovarian
Cancer Program
at the Johns Hopkins Kimmel
Cancer Center.
The researchers, led by Dr Vinay Prasad
at Oregon Health & Science University, say their findings «raise concern that the NCCN justifies the coverage of costly, toxic
cancer drugs
based on weak evidence.»
The idea to specifically study this group of patients was
based on groundbreaking research Garon published in the New England Journal of Medicine last year, which found that among patients who received pembrolizumab, those with PD - L1 expression on
at least 50 percent of their
cancer cells showed the longest survival and disease control.
Prostate
cancer risk groups are assigned
based on the prostate biopsy results, which include the Gleason score (GS)-- an indication of how aggressively the tumor cells may behave — and the prostate specific antigen (PSA) level in the patient's blood
at the time of diagnosis.
«Most scientists would respond well to a speculative email saying that you really love their work and you want to come and work with them,» says Simon Vincent, head of research funding
at Cancer Research UK,
based in London.
Findings were presented
at the WCLC are
based on the updated results of 12 lung
cancer patients enrolled in the clinical trial with pembro and irinotecan or gemcitabine with or without vinorelbine or docetaxel.
«This study forms the
basis for future research in patients with breast
cancer and offers hope for targeted therapy for patients with aggressive triple - negative inflammatory breast
cancer,» said lead researcher Mateusz Opyrchal, M.D., Ph.D., Assistant Professor of Oncology
at RPCI.
«It is anticipated that this novel compound will have significant efficacy in human melanomas and other
cancers either as a stand - alone therapy or in combination with other targeted or immune -
based therapies,» explained co-corresponding author Rhoda Alani, MD, the Herbert Mescon Chair of Dermatology
at Boston University School of Medicine (BUSM).
The NIHR - funded researchers,
based at The Royal Marsden hospital in London, asked 42 breast
cancer patients undergoing radiotherapy to rate how they felt about their body, before the treatment and one month later.
«Complications from thyroid
cancer surgery more common than believed, study finds: Large population -
based study identifies 3 groups most
at risk of post-operative complications.»
«
Based on epidemiological studies, the 9vHPV vaccine could prevent approximately 90 percent of cervical
cancer, 90 percent of HPV - related vulvar and vaginal cancer, 70 to 85 percent of high - grade cervical disease in females, and approximately 90 percent of HPV - related anal cancer and genital warts in males and females worldwide,» explained Anna R. Giuliano, Ph.D., Director of the Center for Infection Research in Cancer at Mo
cancer, 90 percent of HPV - related vulvar and vaginal
cancer, 70 to 85 percent of high - grade cervical disease in females, and approximately 90 percent of HPV - related anal cancer and genital warts in males and females worldwide,» explained Anna R. Giuliano, Ph.D., Director of the Center for Infection Research in Cancer at Mo
cancer, 70 to 85 percent of high - grade cervical disease in females, and approximately 90 percent of HPV - related anal
cancer and genital warts in males and females worldwide,» explained Anna R. Giuliano, Ph.D., Director of the Center for Infection Research in Cancer at Mo
cancer and genital warts in males and females worldwide,» explained Anna R. Giuliano, Ph.D., Director of the Center for Infection Research in
Cancer at Mo
Cancer at Moffitt.
«There are a lot of disparate theories about what could have a profound impact on aging and age - related processes, but
at this point, we simply do not have evidence -
based strategies to significantly change our life expectancy that come in the form of a pill,» says Ronald DePinho, professor of
cancer biology and president of the University of Texas MD Anderson Cancer C
cancer biology and president of the University of Texas MD Anderson
Cancer C
Cancer Center.
Qin; her mentor Elisa V. Bandera, MD, PhD, professor of epidemiology
at Rutgers
Cancer Institute of New Jersey; and fellow researchers evaluated the impact of three index -
based dietary patterns: the 2005 Healthy Eating Index (HEI - 2005), which was
based on the federal Dietary Guidelines for Americans; the 2010 Healthy Eating Index (HEI - 2010), which reflects the most recent dietary guidelines and has an increased emphasis on quality; and the Alternate Healthy Eating Index - 2010 (AHEI - 2010), which is
based on a different nutrition guide, the Healthy Eating Pyramid.
Based on multiple epidemiological studies, the World Health Organization in 2007 and the American Medical Association in 2012 each issued statements warning that extended exposure to light
at night increases the risk of certain
cancers, probably via alterations to circadian rhythms and associated hormone levels.
He's
at higher - than - average risk of developing prostate
cancer, so he should probably check with a urologist on a regular
basis.
«It's very surprising that the nematodes exhibited such a strong binary response to «
cancer» versus «no
cancer» urine,» says Michael Phillips
at Menssana Research, a New Jersey -
based company developing diagnostic tests
based on people's breath.
Breast
cancers that metastasize to the brain are usually deadly, but a team
based at the University of Mississippi Medical Center has discovered a possible fix: a tiny fragment of genetic material known as microRNA.
The team of investigators from Memorial Sloan Kettering
Cancer Center, New York City, analyzed data from the National Cancer Data Base (NCDB) of the American College of Surgeons and the American Cancer Society, and looked at more than 1 million women who underwent mastectomy due to breast cancer between 1998 and
Cancer Center, New York City, analyzed data from the National
Cancer Data Base (NCDB) of the American College of Surgeons and the American Cancer Society, and looked at more than 1 million women who underwent mastectomy due to breast cancer between 1998 and
Cancer Data
Base (NCDB) of the American College of Surgeons and the American
Cancer Society, and looked at more than 1 million women who underwent mastectomy due to breast cancer between 1998 and
Cancer Society, and looked
at more than 1 million women who underwent mastectomy due to breast
cancer between 1998 and
cancer between 1998 and 2011.
The German biotech CureVac, for example, has brought mRNA -
based vaccines for rabies and
cancer to clinical trials, and Karikó now heads a research team
at BioNTech in Mainz, Germany, that focuses on mRNA -
based drugs.
This study used the National
Cancer Data
Base to analyze 9,817 patients and found that patients treated
at higher - volume facilities were more likely to have shorter radiation therapy duration than those
at lower volume facilities.
Qingdong Zheng, a materials scientist
at John Hopkins University in Baltimore, Maryland, suggests that such biolasers could find uses in new types of sensors or in light -
based therapeutics, in which light is used, for example, to kill
cancer cells by triggering drugs into action that have already been administered.
«An MRI -
based protocol for the surveillance of individuals
at risk for developing pancreatic
cancer seems to detect
cancer or premalignant lesions with good accuracy.
A magnetic resonance imaging (MRI)-
based screening program for individuals
at high risk of pancreatic
cancer identified pancreatic lesions in 16 of 40 (40 percent) of patients, of whom 5 five underwent surgery, according to a report published online by JAMA Surgery.
«Further research into the detailed mechanisms underlying ASIS in naked mole - rats may shed new light on
cancer resistance in the mole - rats and contribute to the generation of non-tumorigenic human - iPSCs, enabling safer cell -
based therapeutics,» said Kyoko Miura, an assistant professor
at Hokkaido University.
The study examined 328 patients with cervical
cancer and 1,312 controls, matched on age and decade, who enrolled in a hospital - based case - control study drawn from 26,831 patients who received treatment at Roswell Park Cancer Institute and completed the Patient Epidemiology Data System questionnaire between 1982 and
cancer and 1,312 controls, matched on age and decade, who enrolled in a hospital -
based case - control study drawn from 26,831 patients who received treatment
at Roswell Park
Cancer Institute and completed the Patient Epidemiology Data System questionnaire between 1982 and
Cancer Institute and completed the Patient Epidemiology Data System questionnaire between 1982 and 1998.
Fully implemented targeted sequencing -
based assays in routine diagnostic pathology laboratories are currently lacking in lymphoid
cancer care,» explained Christian Steidl, MD, Senior Scientist at the BC Cancer and Associate Professor in the Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, C
cancer care,» explained Christian Steidl, MD, Senior Scientist
at the BC
Cancer and Associate Professor in the Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, C
Cancer and Associate Professor in the Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, Canada.
Besides working
at IBM's Thomas J. Watson Research Center in Yorktown Heights, New York, Meyer heads something called the DREAM challenges, contests that ask teams of computer scientists to solve outstanding biomedical problems, such as predicting the outcome of prostate
cancer treatment
based on clinical variables or detecting breast
cancer from mammogram data.
There is plenty of anecdotal evidence out there claiming a link between cell phone use and
cancer: Keith Black, chairman of neurosurgery
at Cedars - Sinai Medical Center in Los Angeles, says that the brain
cancer (malignant glioma) that killed O. J. Simpson's attorney, Johnnie Cochran, was the result of frequent cell phone use,
based on the fact that the tumor developed on the side of the head against which he held his phone.
Based on that assumption, many companies tested PKC inhibitors as drugs to treat
cancer, but they didn't work,» said co-senior author Alexandra Newton, PhD, professor of pharmacology
at UC San Diego School of Medicine.
«The PSA test is
based on the fact that men with higher levels of the PSA protein are more likely to have prostate
cancer,» said William Catalona, MD, principal investigator on the Prostate Health Index clinical study and urologist at Northwestern Medicine and director of the Clinical Prostate Cancer Program at the Robert H. Lurie Comprehensive Cancer Center of Northwestern University, where they began using the phi test on patients in Feb
cancer,» said William Catalona, MD, principal investigator on the Prostate Health Index clinical study and urologist
at Northwestern Medicine and director of the Clinical Prostate
Cancer Program at the Robert H. Lurie Comprehensive Cancer Center of Northwestern University, where they began using the phi test on patients in Feb
Cancer Program
at the Robert H. Lurie Comprehensive
Cancer Center of Northwestern University, where they began using the phi test on patients in Feb
Cancer Center of Northwestern University, where they began using the phi test on patients in February.
«It brought me closer to the scientific
basis of disease — you look down the microscope
at the diversity of
cancer and it makes you want to understand more.
Its founder, Allan Bradley, was
at the time
based at the M.D. Anderson
Cancer Research Center in Houston, Texas, and now heads the world's largest mouse genetics program at the Wellcome Trust Sanger Institute, which has a strong cancer comp
Cancer Research Center in Houston, Texas, and now heads the world's largest mouse genetics program
at the Wellcome Trust Sanger Institute, which has a strong
cancer comp
cancer component.