Not exact matches
Our laboratory focuses on the molecular
basis of
cell adhesion to collagen with a focus on the alpha2 beta1 integrin.
Almost all of these small neurons were identified to be cerebellar granule
cells based on their morphology and that they were stained by anti-neural
cell adhesion molecule L1 (Fig. 1A)[19].
Another interesting local network structure is centered around CLU, a gene shown to be involved in AD
based on genome - wide association studies, with genes in the integrin family, involved in
cell adhesion, clustered around CLU.
Based on the glycosylation targets of GalNAc - T6 in the cancer
cell lines, the authors hypothesized that expression of the enzyme disrupts epithelial development in the colon by affecting
cell -
cell adhesion.
The company's antibody -
based product candidates target a number of potential indications including AL and AA forms of amyloidosis, Parkinson's disease and other related synucleinopathies and novel
cell adhesion targets involved in inflammatory diseases and cancers.
Oversaw
cell based assay development, Kinase receptor activation assay (KIRA),
cell adhesion assays, reporter gene assays,
cell bridging assays, and Cytotoxicity assays.