Sentences with phrase «based cell engineering»

Not exact matches

The squeeze system Sharei then designed to temporarily disrupt cell membranes — for which he's been granted most of his 10 patents — is the basis for SQZ Biotech, the company he co-founded in 2013 with the pioneering MIT professors he worked for: Klavs Jensen, the school's head of chemical engineering, and Robert Langer, a renowned bioengineer and serial entrepreneur.

On an additional project with former MIT graduate student Eric Grovender, Ameer co-developed a cartridge filter that purifies blood, «based on protein and cell engineering,» for those suffering from chronic kidney failure.

«Look at all the issues — climate change, stem cell research, general environmental issues, health care, energy — that all have a fundamental scientific or engineering basis.

Some of the other projects involve the development of proton exchange membrane for fuel cell application, a gyroscope based on micro-electromechanical technology and research on innovative engineering materials to fabricate ceramic membranes that can partially oxidize methane to syngas used as feedstock in commercial methanol production.

The authors say that successfully linking digital signals with engineered cells represents an important step toward translating similar cell - based therapies into the clinic.

The engineered protein has two ends: one activates T cells by binding to a surface molecule called the CD3 receptor, and the other — based on an antibody called VRC07 — powerfully binds to more than 90 percent of HIV strains.

The goal of the multi-institutional team is to develop genome engineering - based methods for correcting the disease - causing mutation in each patient's own stem cells to ensure that new red blood cells are healthy.

«You could imagine in the future that all cell towers or Wi - Fi routers could come with our base station technology embedded in it,» said co-author Vamsi Talla, a former UW electrical engineering doctoral student and Allen School research associate.

In 2004 Francis Tay, a mechanical engineering professor in Singapore, invented the MEMSwear device — a tiny silicon - based sensor embedded in a shirt that notices if the wearer has a fall and then communicates an alert to a cell phone or computer via the wireless Bluetooth standard.

Last week cell biologists, software engineers, image analysts, and machine learning experts met in Cambridge, Massachusetts, for a «hackathon» to refine this relatively new approach, generically known as morphological or image - based profiling.

Among the authors, only Charles Vacanti, an anesthesiologist and tissue engineering specialist based at Brigham and Women's Hospital in Boston, says his lab can make STAP cells.

If an endorsement by Ted Kennedy, Dick Cheney's daughter, The New York Times or even Chuck Norris isn't enough to thrust you onto a particular presidential candidate's bandwagon, the Scientists & Engineers for America, a nonpartisan organization that advocates evidence - based debate and decision - making in Washington, offers another metric: their science platforms.Examining subjects like energy policy, healthcare, views on evolution, stem cells and the like, the Science, Health and Related Policies (SHARP) Network unfurls each candidate's positions (and past) in a wiki format.

«This cell - targeted EPO approach demonstrates a new theoretical basis for the rational design of engineered protein fusion drugs.»

In 2005, Mr Sipes returned to GNF and is now working with a team of scientists and engineers to develop and operate next generation automation for high throughput screening and cell - based profiling.

«Our original hypothesis was that cancer cells were modifying their metabolism based on communications they were receiving from cells in the microenvironment near the tumor,» said Nagrath, assistant professor of chemical and biomolecular engineering at Rice and co-author of a new study describing the research in the open - access journal eLife.

A significant advantage of ZFN gene modification, compared to retrovirus based approaches, is that only transient transgene expression is required to permanently engineer an HIV resistant cell.

This is our dream for personalized cancer therapy, so we're not just guessing any more about which drugs will work but can choose drug targets based on what's driving that patient's cancer,» said Josh Stuart, the Baskin professor of biomolecular engineering at UC Santa Cruz, director of cancer and stem cell genomics at the UCSC Genomics Institute, and a senior corresponding author of the paper.

The means to enhance the production of cartilage - specific extracellular matrix is needed for cell - based tissue engineering applications, since cultured chondrocytes quickly lose their cartilage - specific phenotype.

The safe use of a stem - cell - based therapy against brain metastasis would require preventing the engineered cells from persisting within the brain, where they could affect normal tissue and possibly give rise to new tumors.

The multidisciplinary Southampton team, led by Dr Jessica Teeling, and in collaboration with Lundbeck (a multinational pharmaceutical company based in Denmark), engineered three antibodies to change the way they engage cells in the immune system.

Thus, Rho - kinase inhibition at low oxygen tension can be regarded as a potential way to enhance extracellular matrix production and maintain a chondrocyte phenotype in cell - based tissue engineering applications.

Verma was the first scientist to genetically engineer HIV - based tools to insert new genes into cells.

BERKELEY, CA, and CORALVILLE, IA — February 23, 2016 — Caribou Biosciences, Inc., a developer of CRISPR technologies for precision cell engineering, and Integrated DNA Technologies, Inc. (IDT), a producer of custom synthetic oligonucleotide - based technologies for genomics applications, have entered into a non-exclusive license agreement under which Caribou has granted IDT worldwide rights to commercialize CRISPR - Cas9 reagents under Caribou's intellectual property.

Dib has developed the methods of catheter base stem cell transplantation to treat myocardial infarction using 3 - dimensional guidance technology, and has edited a book on stem cell transplantation and tissue engineering for cardiovascular repair.

INGESTEM, the national infrastructure in biology and health certified by the «Investissements d'Avenir» program and the Ile - de-France Region (DIM Biothérapies), is the first French network of therapeutic innovations based on pluripotent stem cells, human tissue engineering and their biomedical applications.

Scaffold - based bone engineering by using genetically modified cells.

Ovine bone - and marrow - derived progenitor cells and their potential for scaffold - based bone tissue engineering applications in vitro and in vivo.

Glycocalyx engineering reveals a Siglec - based mechanism for NK cell immunoevasion.

The paper details the computational modeling work to define a new type of responsive material system based on genetically engineered bacteria cells.

The development of diagnostic and therapeutic nanodevices based on engineered recombinant proteins capable of recognizing specific tumor cell receptors is currently actively pursued.

We are developing tools to engineer proteins in living cells based on genetic code expansion and unnatural amino acid mutagenesis.

We will be developing tools to engineer proteins in living cells based on genetic code expansion and unnatural amino acid mutagenesis.

Stem cell ‐ based therapies under investigation as a strategy for the treatment of Type 1 diabetes mellitus (T1DM) include the differentiation of cells towards engineered β cells [1] and the use of mesenchymal stem cells (MSCs) in the prevention or reversal of autoimmune and chemical ‐ induced diabetes [2].

Georgia Tech Engineers created an organization to develop standards and production processes designed to mass produce life - saving cell - based therapeutics at affordable prices.

With this approach, scientists can develop cell - based therapies that use engineered cells from the immune system as the «drug».

Two research projects based at SciLifeLab have been granted funding from the Chan Zuckerberg Initiative, which was formed by Facebook founder Mark Zuckerberg and his wife, Dr. Priscilla Chan, and provides financial and engineering support for the Human Cell Atlas — an ambitious international collaboration that aims to create a reference atlas of all cells in the healthy -LSB-...]

While these kinds of engineered cells are not new, the new light - based technique promises much greater control over how much insulin is delivered at any given time.

Molecular cell bioengineering is the application of engineering approaches to develop quantitative understanding of cell function in terms of fundamental molecular properties, and to apply this understanding for improved design of molecular - and cell - based technologies.

Stem Cells Translational Medicine welcomes original articles and concise reviews describing the clinically relevant translational aspects of stem cells and progenitor cells for cell - based therapy, tissue engineering and regenerative medicine from the bench to patient Cells Translational Medicine welcomes original articles and concise reviews describing the clinically relevant translational aspects of stem cells and progenitor cells for cell - based therapy, tissue engineering and regenerative medicine from the bench to patient cells and progenitor cells for cell - based therapy, tissue engineering and regenerative medicine from the bench to patient cells for cell - based therapy, tissue engineering and regenerative medicine from the bench to patient care.

Khaleel was selected based on his international leadership in computational engineering sciences and fuel cell technology.

Our results suggest that co-expression of active SMAD2 / 3 could enhance multiple types of TF - based cell identity conversion and therefore be a powerful tool for cellular engineering.

At Roswell Park, along with his translational lab research, Dr. Koya leads an NIH funded prospective clinical trial based on an immune - modulator - enhanced TCR - engineered T cell transfer for metastatic cancer patients.

Of course, if we own products based on genetically engineered organisms, we will have to evaluate and control the risks of those unnatural living cells spread widely throughout our environment.

«What we've shown is that a graphene - based system can detect the activity of a cell, and by doing that we can differentiate between a cancer cell and a normal cell,» Vikas Berry, associate professor and head of chemical engineering at UIC, told Digital Trends.

Please apply directly to this positing Responsibilities • Provide level 1st & 2nd level technical assistance in analyzing, diagnosing, replicating and troubleshooting customers reported issues to resolution on Microsoft Windows 7 OS • Manage assigned support incidents and maintain up - to - date status in the Numara Ticketing Systems Console - Escalate unresolved issues that require more in - depth knowledge to engineering in a timely manner • Teach new employees on basic computer, Wi - Fi, and cell phone features & functionality • Create reproducible test cases, when necessary, for customer reported issues - Report and submit product defects in the bug tracking system - Create new knowledgebase articles and keep them up - to - date - Provide after business hour support on a rotation basis • Image and configure new PC equipment for deployment (MS MDT, SCCM, Numara) • Keep Technical Support equipment organized and readily available for deployment • Deploy hardware and software to employees Qualifications • Bachelor's degree in Computer Science or related field of studies • Comfortable teaching large groups • Knowledge of Dell Laptops and repair • Strong analytical, troubleshooting, and problem solving skills • Extensive Windows 7 knowledge • Databases, preferably, SQL Server • Read and understand log and config files • Support, QA, training or field experience with enterprise software, preferably monitoring and / or performance suites, or system administration experience • Experience creating documentation, procedures, and knowledge base entries • Excellent written and verbal communication skills required • Excellent customer service skills required Please apply directly to this positing.

Professional Duties & Responsibilities Biomedical and biotechnology engineer with background in design of biomaterials, biosensors, drug delivery devices, microfrabrication, and tissue engineering Working knowledge of direct cell writing and rapid prototyping Experience fabricating nanocomposite hydrogel scaffolds Proficient in material analysis, mechanical, biochemical, and morphological testing of synthetic and biological materials Extensive experience in bio-imaging processes and procedures Specialized in mammalian, microbial, and viral cell culture Working knowledge of lab techniques and instruments including electrophoresis, chromatography, microscopy, spectroscopy, PCR, Flow cytometery, protein assay, DNA isolation techniques, polymer synthesis and characterization, and synthetic fiber production Developed strong knowledge of FDA, GLP, GMP, GCP, and GDP regulatory requirements Created biocompatible photocurable hydrogels for cell immobilization Formulated cell friendly prepolymer formulation Performed surface modification of nano - particle fillers to enhance their biocompatibility Evaluated cell and biomaterial interaction, cell growth, and proliferation Designed bench - top experiments and protocols to simulate in vivo situations Designed hydrogel based microfluidic prototypes for cell entrapment and cell culture utilizing computer - aided robotic dispenser Determined various mechanical, morphological, and transport properties of photocured hydrogels using Instron, FTIR, EDX, X-ray diffraction, DSC, TGA, and DMA Assessed biocompatibility of hydrogels and physiology of entrapped cells Evaluated intracellular and extracellular reactions of entrapped cells on spatial and temporal scales using optical, confocal, fluorescence, atomic force, and scanning electron microscopies Designed various biochemical assays Developed thermosensitive PET membranes for transdermal drug delivery application using Gamma radiation induced graft co-polymerization of N - isopropyl acylamide and Acrylic acid Characterized grafted co-polymer using various polymer characterization techniques Manipulated lower critical solution temperature of grafted thermosensitive co-polymer Loaded antibiotic on grafted co-polymer and determined drug release profile with temperature Determined biomechanical and biochemical properties of biological gels isolated from marine organisms Analyzed morphological and mechanical properties of metal coated yarns using SEM and Instron Performed analytical work on pharmaceutical formulations using gas and high performance liquid chromatography Performed market research and analysis for medical textile company Developed and implement comprehensive marketing and sales campaign

I had included the address on mls so XXXX Drive, XXXXXXXXX Ontario, Owners (via cross reference) Mr XXXX and Mrs. XXXX, Age Mid to Late 30 ′ s Phone number 905XXXXXXX 2 children Boy 8 - 10 - plays soccer and lacrosse, favorite color blue, plays piano Girl 11 - 13 - plays soccer and ringette, favorite color yellow, likes unicorns, has ipod and cell phone Family is Catholic He has post secondary education He attended Queens He is an engineer He may have a motorcycle (this was correct too) They purchase foreign brand cars She is Stay at Home Mom She has post secondary education She has some degree She is over weight and trying to lose it She Scrap books She uses the internet regularly She uses a Mac He uses a PC They have a small dog (probably female)(correct again) The dog does not jump up on doors They use Royal Bank They vacation South in Winter (Mexico regular place) They prefer neutral colors She still likes dolls They prefer Sony products and Apple They have an alarm system The alarm is based on motion sensors The windows have no contact sensors The side door is often unlocked The patio doors have no security bars The Basement windows have no curtains The rear yard is accessible from the back They use their hot tub regularly They are not the original owners They drink red wine They drink bottled water They own 2 vehicles She comes from a big family.

I had included the address so XXXXQuail Valley Drive, XXXXXXXXX Ontario, Owners (via cross reference) Mr XXXX and Mrs. XXXX, Age Mid to Late 30 ′ s Phone number 905XXXXXXX 2 children Boy 8 - 10 - plays soccer and lacrosse, favorite color blue, plays piano Girl 11 - 13 - plays soccer and ringette, favorite color yellow, likes unicorns, has ipod and cell phone Family is Catholic He has post secondary education He attended Queens He is an engineer He may have a motorcycle (this was correct too) They purchase foreign brand cars She is Stay at Home Mom She has post secondary education She has some degree She is over weight and trying to lose it She Scrap books She uses the internet regularly She uses a Mac He uses a PC They have a small dog (probably female)(correct again) The dog does not jump up on doors They use Royal Bank They vacation South in Winter (Mexico regular place) They prefer neutral colors She still likes dolls They prefer Sony products and Apple They have an alarm system The alarm is based on motion sensors The windows have no contact sensors The side door is often unlocked The patio doors have no security bars The Basement windows have no curtains The rear yard is accessible from the back They use their hot tub regularly They are not the original owners They drink red wine They drink bottled water They own 2 vehicles She comes from a big family.