In the past, Western - type diets have been made by adding high levels of fat and cholesterol to grain -
based chow diets.
Since the ingredients used are so highly refined, purified diets lack the hundreds of plantderived phytochemicals that are found in grain -
based chow diets.
With the availability of this remarkable tool, it's hard to understand why so many researchers continue to use grain -
based chow diets in nutrition studies and even, as we shall see, in studies that are not necessarily nutrition - oriented, such as drug and compound efficacy studies, or behavioral studies.
Not exact matches
Animals were fed a mouse
chow low in fat and rich in plant polysaccharides, or one of two
diets reflecting the upper or lower tertiles of consumption of saturated fats and fruits and vegetables
based on the U.S. National Health and Nutrition Examination Survey (NHANES).
For four weeks, the researchers fed mice either a grain -
based rodent
chow, a high - fat
diet (high fat and low fiber content with 5 percent cellulose as a source of fiber) or a high - fat
diet supplemented with fiber (either fermentable inulin fiber or insoluble cellulose fiber).
It turned out, the mice ate a vegetable -
based chow — essentially a low - fat vegan
diet that bore little resemblance to that of the average American male.
In 2008, Kozul - Horvath and Hamilton's found that mice fed a grain -
based chow (Purina 5001) had no changes in gene expression when exposed to arsenic while they were dramatic when fed purified
diet AIN - 76A (Click here for pdf...
The model was
based loosely on published work by (1) Surwit et al. (1995) and (2) West et al. (1995), in which a
chow -
based, undefined
diets were used to study the DIO phenotype in inbred mouse strains.
For example, in many cases a
chow (cereal
based diet) is used as a low - fat «control»
diet for a purified high - fat
diet.
Purified ingredient OpenSource
diets differ greatly from grain -
based diets (
chows) in their composition.
This requires that researchers understand the differences between grain -
based (GB)
chows and purified ingredient
diets, and unfortunately, many investigators (immunologists or not) are unaware of these differences.
Understandably, many researchers are reluctant to switch from grain -
based chows to purified
diets.
Furthermore, casein -
based purified
diets contain no phytoestrogens (or other phytochemicals) unlike typical grain -
based chows which can have highly variable levels (6).
Raw dairy products, bone broths and soups
based on broth, and lacto - fermented foods are important elements in a
diet for those would - be centenarians who wish to do more than sit in the corner «munching contentedly» on their
chow.
«Herein, we examined if, relative to a grain -
based mouse
diet (
chow), compositionally defined
diet consumption would impact development of intestinal inflammation induced by dextran sulfate sodium (DSS) and moreover, whether DSS - induced colitis might also be attenuated by
diets supplemented with inulin.
Generally, we find that your average French Bulldog in good health does well with a
diet rich in carbs from sweet potatoes, or sweet potato -
based chows, protein from various fatty avian varieties like duck, pheasant, or chicken and from fatty fish varieties such as salmon.