Sentences with phrase «based exosome»

Not exact matches

We have found that exosomes and the cargo they contain are crucial mediators of stem cell - based heart regeneration, and we believe this might lead to an even more refined therapy using the «active ingredient» instead of the entire stem cell,» said Eduardo Marbán, MD, PhD, director of the Cedars - Sinai Heart Institute and a pioneer in developing investigational cardiac stem cell treatments.

Intrigued, the Martinsried - based team set up an elaborate experimental study to purify the exosomes from different cell types, including neurons, and analyse their contents.

Cancer cells settle to the bottom of the well, where they selectively bind to the antibodies based on their surface markers (unlike other devices, the chip can also trap tiny structures called exosomes produced by cancers cells).

The exosome study began four years ago based upon a growing realization that exosomes might play a role in regulating cancer metabolism.

«Based on our findings, the next phase will be to measure exosomes and exomeres in plasma samples to help predict organs that may be targeted for metastasis during tumor progression,» said Dr. Lyden.

This is the first biomarker discovery based on extracellular vesicles in a veterinary disease; genomic material (microRNA, or miRNA) was isolated in small extracellular vesicles, or exosomes, circulating in blood, according to Cummings.