Sentences with phrase «based functional studies»

This network funds pilot studies to expedite collaboration between the two groups, conduct model organism - based functional studies of disease gene variants, and develop new therapeutic strategies using model organisms.

Not exact matches

The neural bases of numerosity processing have been investigated in structural and functional neuroimaging studies of adults and children, and neural markers of its impairment in dyscalculia have been identified.

This hypothesis is supported by studies of comparative morphological and functional anatomy, which are based on the recognition of structural similarities between the basic body plans of the various animal groups.

In this new study and for the first time, scientists used functional magnetic resonance imaging (fMRI) combined with a standard clinical trial design to derive an unbiased brain - based neurological marker to predict analgesia associated with placebo treatment in patients with chronic knee osteoarthritis pain.

So far, studies in this field have mainly been based on functional magnetic resonance imaging (fMRI).

Dr. Aron and colleagues based their study's conclusions on a neuroimaging study using functional magnetic resonance imaging (fMRI) scanning that measures brain activity by detecting changes in blood flow.

Led by neurologist Bradley Schlaggar, the group studied 238 healthy volunteers, 7 to 30 years old, using functional MRI, a technique that identifies active neural circuits based on blood flow and blood oxygen levels.

Johnson, along with study co-author and post-doctoral researcher Jingyun Ye at the University of Pittsburgh, examined a series of eight different functional groups of Lewis acid and base pairs (Lewis pairs for short), which are highly reactive compounds often used as catalysts.

Dr Leonardo Guasti added: «It represents an entirely new concept for the study of the adrenal gland as the ability to generate donor - specific and functional adrenal - like cells will facilitate the next generation of cell - based treatments for adrenal insufficiency, the modelling of adrenal specific diseases, and the testing of personalised interventions on cells derived from patients.»

In recent years, songbirds» similarities to human vocal learning have piqued researchers» interests in using them as a functional animal model to study the neurological basis for Huntington's disease.

Using functional magnetic resonance imaging (fMRI), an imaging technique that measures brain activity, researchers examined all three groups at the beginning (baseline), middle, and end of the study while participants performed computer - based speed tasks in the scanner.

Since its discovery in the early 1990s, functional MRI has been the basis for more than 19,000 studies of the living, working brain.

To address these limitations, Zimmer and senior study author Lorenz Studer of the Sloan Kettering Institute for Cancer Research developed a simple, efficient, and robust stem cell - based strategy for reliably producing a large number of diverse, functional pituitary cell types suitable for therapeutic use.

Still, Sheehan said neuroscience already is one of the leaders in data sharing and management, with such resources as the NIH - funded National Database for Autism Research; an NIH - Defense Department sponsored data base on traumatic brain injury; the NIH - funded Neuroimaging Informatics Tools and Resources Clearinghouse (NITRC), which helps researchers to develop, share and collaborate on software tools for doing functional and structural imaging studies of the brain; and the Neuroscience Information Framework, an NIH initiative that makes neuroscience resources - data, materials, and tools - accessible via any computer connected to the Internet.

«This study is a major step forward for plant - based MAbs, and also demonstrates for the first time the capacity of plants to express and assemble large, complex and functional tetravalent MAb complexes,» said Chen.

Furthermore, their study reveals novel physical as well as functional links to phosphatase - based regulation of human cancer.

The complete list is: the Food Research Center; the Center for Research, Teaching, and Innovation in Glass; the Center for Research and Development of Functional Materials; the Brazilian Research Institute for Neuroscience and Neurotechnology; the Center for Research on Inflammatory Diseases; the Center for Research and Innovation in Biodiversity and Drug Discovery; the Center for Research on Toxins, Immune Response, and Cell Signaling; the Research, Innovation and Dissemination Center for Neuromathematics; the Center for Research in Mathematical Sciences Applied to Industry; the Obesity and Co-Morbidities Research Center; the Center for Cell - Based Therapy; the Center for Metropolitan Studies; the Human Genome and Stem - Cell Research Center; the Center for Computational Science and Engineering; the Center for Research on Redox Processes in Biomedicine; the Center for the Study of Violence; and the Optics and Photonics Research Center.

Functional magnetic resonance imaging (fMRI) used in the study showed activity in a part of the brain called the ventral striatum — which has been shown to guide goals based on prior experiences.

«Additional recordings with FO electrodes in patients with Alzheimer's disease will help us develop better tools based on computerized analysis of EEG signals and possibly functional neuroimaging studies to ascertain how common silent seizures are in Alzheimer's disease without the need for the minimally invasive electrodes we used in these patients.»

«We need to follow up with functional studies, such as in animal models or at least in vitro systems, to pinpoint and validate the biological basis for selection.»

This, in my opinion, is one of the most compelling parts of this study: in vivo functional validation of a single base change in a noncoding enhancer that's hundreds of thousands of bases away from the gene it regulates.

Phonon properties have been studied by Green's functions phonon transport method through Density Functional based Tight Binding theory, implemented into DFTB package.

Dr. Sucheston - Campbell will present a companion presentation based on this research, «Functional Genetic Variants on 14q32 Associate with Death Due to Acute Myeloid Leukemia (AML) and Myelodysplastic Syndrome (MDS) within One Year after HLA - Matched Unrelated Donor Blood and Marrow Transplantation (DISCOVeRY - BMT Study),» on Saturday, Feb. 25, 6 p.m. at Gaylord Palms Convention Center, Florida Hall C. Dr. Hahn is senior author of that presentation.

Common and distinct neural correlates of emotional processing in Bipolar Disorder and Major Depressive Disorder: a voxel - based meta - analysis of functional magnetic resonance imaging studies.

This observation suggests that the bulk of genes involved in Nasonia immune response remain uncharacterized, with the current study being the first identification of additional candidate genes for immunity based on functional response to infection.

Ageing research and more generally the study of the functional basis of human diseases profit enormously from the large - scale approaches and resources in mouse functional genomics: systematic targeted mutation of the mouse genome, systemic phenotyping in mouse clinics, and the archiving and distribution of the mouse resources in public repositories.

We demonstrate that a comprehensive characterization of immune - induced transcripts is feasible using transcriptome sequencing in combination with homology - based methods, paving the way for more detailed functional studies in a wider range of species and a more complete understanding of the degree to which Hymenoptera possess novel immune pathways.

Both task - based and resting - state fMRI have been applied to the study of functional connectivity in ASD.

Below we survey fMRI studies of ASD examining task - based functional connectivity and resting - state functional connectivity with the goal of providing an overview of the existing literature and highlighting the dearth of developmental studies of functional connectivity in ASD.

Across the subregions, GAD patients had increased connectivity with a previously characterized frontoparietal executive control network and decreased connectivity with an insula - and cingulate - based salience network.Our findings provide new insights into the functional neuroanatomy of the human amygdala and converge with connectivity studies in experimental animals.

Laboratory activities minimally include performing a lab - based patient - oriented research project applicable to cancer genomics, with an emphasis on mastering techniques commonly used within a human genetics laboratory, such as PCR, gene sequencing, mutation analysis, western blots, and functional protein studies.

«This study is purely based on differences in morphological characters between fossil specimens, with each character weighted equally, and with disregard of any functional aspects of every character,» says Dr. Gerrit van den Bergh of the University of Wollongong in New South Wales, one of the authors of the 2016 study published in Nature that supports the idea that H. floresiensis descended from H. erectus and was made small by insular dwarfism.

Although the ERP study by Koelsch and colleagues11 controlled for the possibility of processing musical sequences in a strictly local fashion, the precise neuro - functional basis of processing non-local dependencies in music nevertheless remains unknown.

The current study was thus conducted to assess the functional basis of processing non-local dependencies in music in the human brain, whilst controlling for local transition probabilities.

The Department of Microbiology of the Yonsei University College of Medicine, is investigating on identification and functional study of virulence determinants in Mycobacterium tuberculosis by comparative genome - based analysis.

This study provides a genome editing - based multiplex strategy for direct functional interrogation of RNA cis - regulatory elements in a native cellular environment.

While the Anopheline Y had previously been implicated in male mating behavior, recent data from the Anopheles gambiae complex suggests that, apart from the putative primary sex - determiner, no other genes are conserved on the Y. Studying the functional basis of the evolutionary divergence of the Y chromosome in the gambiae complex is complicated by complete F1 male hybrid sterility.

The behavioral and neuronal bases of executive function have been well studied in neuropsychological patients (12 ⇓ — 14) and with functional neuroimaging (9, 12, 15 ⇓ — 17), which confirm that executive function is supported by a network of brain regions, primarily involving the frontal lobes and the posterior parietal cortex (9, 12, 15 ⇓ — 17).

In contrast to fcMRI analyses that define networks based on intrinsic connectivity, most functional imaging studies employ cognitive subtraction paradigms.

It fosters independence Simple resistance training can improve muscle strength, power, and functional performance in people over the age of 65, say Australian researchers who studied a twice - weekly, machine - based program that targeted major muscles of the upper and lower body.

The 27 - year - old athlete is also studying functional medicine, and her vision for an integrative, community - based approach to healing might just be the next big thing in wellness.

IFNA's 5th Track entitled The Case Study Immersion or «CSI Track» is designed to give you even more case - based opportunities to immerse, investigate and integrate the functional nutrition care process into your own practices!

The Case Study Immersion or «CSI Track» designed to give you even more case - based opportunities to immerse, investigate and integrate the functional nutrition care process into your own practices!

The Case Study Immersion or «CSI Track» is designed to give you even more case - based opportunities to immerse, investigate and integrate the functional nutrition care process into your own practices!

The beautiful thing is that when we restore vitality and energy, the human body shows its amazing capacity to healMy approach is based on my education at The Institute for Integrative Nutrition where I studied over 100 different dietary theories and learned from some of the best minds in nutrition and functional medicine.

So instead of always being harmful, particularly in men, plant - based phytoestrogens may serve the functional purpose of blocking harmful estrogens from feeding hormone - related cancers, as illustrated in several studies, including a 2005 study published in the journal Clinical Cancer Research.

Montmorency tart cherry juice, compared to a placebo, was found to maintain greater functional performance, impact a key marker of inflammation and decrease self - reported muscle soreness among study participants following prolonged activity that mirrors the demands of field - based sports.

On this basis, a ketogenic diet has been proposed as a collateral therapeutic approach in this disease.95 Studies by Zhao et al. 96 revealed both histological and functional improvements in an animal model of amyotrophic lateral sclerosis when a ketogenic diet was given compared with when given a control diet.

â $ cents Conduct a doseâ $ «response study to determine the amount of fiber that needs to be ingested to promote optimum laxation so that this could form the basis for a recommendation for fiber intake and provide a basis for determining functional fibers.

In connection with this review, the DOT will request that the project sponsor provide a feasibility study (as applicable) and a fully functional Microsoft Excel - based financial model.