Sentences with phrase «based therapy»

These two properties (self - renewal and pluripotency) confers human pluripotent stem cells a unique interest for clinical applications since they could allow the production of infinite quantities of cells for disease modelling, drug screening and cell based therapy.

Stem Cell Therapy company presents a collection of stem cell - based therapy summaries for multiple diseases such as diabetes, liver disease, lung disease, osteoarthritis and more.

The latter factor determines the specificity of NP - and PNB - based diagnosis and the efficacy and selectivity of the NP - and PNB - based therapy.

I decided that my new lab would work on understanding the T - cell response to HIV and why these cells fail to control the infection, with an eye towards developing immune - based therapy.

ReliNethra ® is the first stem cell - based therapy in the country.

â $ œAlthough iPS cell technology has enormous potential for biomedical research and cell - based therapy, it is still in its early stage and significant obstacles must be overcome in order to realize its full potential.

The gift allowed Memorial Sloan Kettering to establish a state - of - the - art collaborative research center focused on immune - system - based therapy, an approach showing great promise in the treatment of cancer and several other diseases.

Stem Cells Translational Medicine welcomes original articles and concise reviews describing the clinically relevant translational aspects of stem cells and progenitor cells for cell - based therapy, tissue engineering and regenerative medicine from the bench to patient care.

Progress and challenges in the development of a cell - based therapy for hemophilia A. J Thromb Haemost.

However, as proposed for the T790M mutation in the EGFR, 31 the significant gain - of - function property conferred by the mutations that we describe here may favor their initial presence before drug selection, and rapid selection during tyrosine kinase inhibitor - based therapy.

Navigating the legal minefield — what clinicians and patients need to know before undertaking a cell - based therapy treatment

Ultimately, we use all this information to establish innovative culture techniques for generating unlimited neural stem cell sources for the derivation of specific types of clinically relevant neuronal or glial cells, for their use in disease modelling and drug discovery platforms, and towards refining their efficacy for future cell replacement - based therapy.

The first stem - cell - based therapy was a bone marrow transplant used to treat leukemia.

The US Food and Drug Administration's linkurl: decision; https://www.the-scientist.com/blog/display/55353/ to green light a human embryonic stem cell - based therapy for spinal cord injury isn't just good news for the biotech in question, Geron Corp., analysts say — instead, they argue, the move opens the door to an entire market that has heretofore been stymied.

Therefore, experts would still favor docetaxel - based therapy, with or without ramucirumab, following a platinum doublet.

For only the second time, the Food and Drug Administration approved a company's request to test an embryonic stem cell - based therapy on human patients.

The resultant clones with functional FIX can then be screened for integration of the viral backbone in safe harbor regions and for its robust expression, subsequent to which they will be differentiated in vitro to the hepatic lineage, with a view to producing a cell - based therapy for hemophilia.

The research team now concentrates on using CBS - based therapy in other animal infection models, e.g. urinary tract infection (UTI), hoping to offer a more extensive approach to combat with antibiotic resistant superbugs.

Robin's research is focused on the genetic regulation of metastasis, primarily in breast cancer and is aimed at identifying new targets for molecular based therapy for patients with progressive disease.

This bismuth drug - based therapy looks set to become the last - line strategy against superbugs infections apart from development of new antibiotics.

«'' Yet again, a world - class team of scientists has suggested another novel cell - based therapy for diabetes.

Our researchers have identified a bacterial - based therapy for attacking pancreatic tumors, offering hope in the fight against one of the deadliest cancers.

He explained that bone marrow transplants are the only routine stem cell - based therapy worldwide.

Phase I / II study of inhaled doxorubicin combined with platinum - based therapy for advanced non-small cell lung cancer.

The symposium brings together leaders in biology, medicine, and industry to present on the latest advances in technology development, mechanistic understanding, and therapeutic application of stem cells for both drug development and cell - based therapy.

Interneuron cell - based therapy in AD and related models: During brain development, embryonic interneuron precursors are generated in the medial ganglionic eminence (MGE) and retain a remarkable capacity for migration and integration in adult host brains, where they fully mature into functional inhibitory interneurons.

Then, in May, the FDA put a hold on California - based Geron's clinical trial of an ESC - based therapy to treat spinal cord injury.

Thus, MGE, or MGE - like, precursors provide a great opportunity for cell - based therapy in animal models of neurological disorders linked to impaired inhibitory function.

She added that while investigators are not sure yet how therapeutic approaches would be implemented, having the understanding of how to identify olfactory cues and use the information as part of exposure - based therapy sessions is extremely promising.

This new system, developed by Hocoma (http://www.hocoma.com/en/), a Swiss - based manufacturer, offers appropriate patients an intensive program of activity - based therapy that has been shown to improve overall function, movement and walking.

It is also funding research aimed at a stem cell - based therapy for Parkinson's disease that is expected to lead to a clinical trial.

«Activity - based therapy and exercise is essential for someone who has experienced a spinal cord injury,» said Susan J. Harkema, PhD, NeuroRecovery Network Director for the Reeve Foundation, Director of Research at Frazier Rehab Institute, Professor and Rehabilitation Research Director at the University of Louisville Kentucky Spinal Cord Injury Research Center and Owsley B. Frazier Chair in Clinical Rehabilitation Research.

These in turn can be used for disease modeling and drug discovery, but hopefully one day also for cell - based therapy of the many devastating diseases such as Alzheimer and Parkinson's Disease.

We are evaluating the therapeutic potential of interneuron - based interventions by using cell - based therapy and pharmacology.

«Stem cell - based therapy for targeting skin - to - brain cancer: Stem cells loaded with oncolytic viruses show promising results in preclinical models for targeting skin cancer metastases in the brain.»

«Stem - cell - based therapy promising for treatment of breast cancer metastases in the brain.»

The safe use of a stem - cell - based therapy against brain metastasis would require preventing the engineered cells from persisting within the brain, where they could affect normal tissue and possibly give rise to new tumors.

The main exception was that patients with few psychiatric problems and «meaning - seekers» did better with the AA - based therapy.

Investigators from Massachusetts General Hospital (MGH) and the Harvard Stem Cell Institute have developed an imageable mouse model of brain - metastatic breast cancer and shown the potential of a stem - cell - based therapy to eliminate metastatic cells from the brain and prolong survival.

Continuing medical education targeting improvements in office - based therapy for opioid abuse.

«Our research shows that the presence of lymphocytes before administering chemotherapy could predict a positive response to platinum - based therapy.»

«The fact that a microtubule - based therapy would correct the problem with dopamine release is really encouraging,» Baas said.

NRG Oncology researchers recently developed and validated a nomogram that can predict 2 - year and 5 - year overall survival (OS) and progression - free survival (PFS) for patients with local - regionally advanced oropharyngeal squamous cell carcinoma (OPSCC) treated primarily with radiation - based therapy.

Patients report satisfaction with VR - based therapy, and in some cases find it more acceptable than traditional therapy.

The study builds on previous St. Jude research that has helped to revolutionize understanding of the origins of medulloblastoma and laid the foundation for a new era of risk - based therapy.

The field has waited a very long time — decades, really — for a genetically - inspired, mechanism - based therapy.

Experts had realized that retrovirus - based therapy might cause cancer, he explains, but the risk seemed very small.

Ultimately, however, these insights could broaden the repertoire of tissues that can be generated from stem cells, with significant implications for regenerative medicine and stem cell - based therapy.

The complete list is: the Food Research Center; the Center for Research, Teaching, and Innovation in Glass; the Center for Research and Development of Functional Materials; the Brazilian Research Institute for Neuroscience and Neurotechnology; the Center for Research on Inflammatory Diseases; the Center for Research and Innovation in Biodiversity and Drug Discovery; the Center for Research on Toxins, Immune Response, and Cell Signaling; the Research, Innovation and Dissemination Center for Neuromathematics; the Center for Research in Mathematical Sciences Applied to Industry; the Obesity and Co-Morbidities Research Center; the Center for Cell - Based Therapy; the Center for Metropolitan Studies; the Human Genome and Stem - Cell Research Center; the Center for Computational Science and Engineering; the Center for Research on Redox Processes in Biomedicine; the Center for the Study of Violence; and the Optics and Photonics Research Center.

The Center for Cell - Based Therapy at the University of São Paulo was one of three centers to receive funding in both the first and second rounds of the RIDC program.