Sentences with phrase «based vaccine approach»

They will also work with Vir Biotechnology, Inc. of San Francisco, which has licensed aspects of their CMV - based vaccine approach, to expand testing with plans to start a human clinical trial in 2020.

Not exact matches

«What that suggests is that this approach really gives us broad spectrum protection, and could serve as a basis for an effective pre-pandemic vaccine.»

Researchers for the past decade have focused on the T cell approach, based on studies showing that monkeys receiving such vaccines against simian immunodeficiency virus, related to HIV, lived longer or had lower viral levels than usual.

The advantage of Novavax's approach is that a vaccine can be made rapidly and in high volume, compared with the egg - based approach that's used today, says Ted Ross, an associate professor of microbiology and molecular genetics at the University of Pittsburgh's Center for Vaccine Researchvaccine can be made rapidly and in high volume, compared with the egg - based approach that's used today, says Ted Ross, an associate professor of microbiology and molecular genetics at the University of Pittsburgh's Center for Vaccine ResearchVaccine Research (CVR).

The success of both vaccines thus far in stringent monkey models has led Picker and his colleagues to believe their CMV - based approach to making vaccines has the potential to be engineered to tackle a variety of infectious diseases.

Phages would require a less traditional approach to get official approval, such as the annual process for influenza vaccines in which manufacturers secure approval of new formulas based on the flu bug that is going around that year, instead of conducting big clinical trials every time.

For example, although early clinical trials of Listeria - based vaccines have shown that the neutralized bacterium produces only mild flulike symptoms in human patients with cervical cancer, the various methods of genetically disarming the bacteria should be explored to find the safest approach for people gravely ill with pancreatic cancer, because these patients are likely to already have weak immune systems.

There are ongoing studies which focus on the discovery of molecular biomarkers of the VSV - ZEBOV vaccine in healthy individuals using omics - based technologies in combination with a systems biology approach,» says Ali Harandi.

A vaccine based on this approach would need to work in tandem with others aimed at different parts of the cycle, Kurtis cautions.

«This broad implication is in contrast to a more traditional vaccine - based approach, which requires a specialist to surgically remove tumor samples from a patient's body then create a personalized vaccine approach for one specific patient.»

Those who oppose the trial think the approach with the greatest chance of success would be to test a vaccine based on one subtype in a population at risk from the same subtype.

For their pioneering discoveries in chemistry and parasitology, and personal commitments to translate these into effective chemotherapeutic and vaccine - based approaches to control malaria - their collective work will impact millions of lives globally particularly in the developing countries.

Our platform includes two distinct approaches to create these vaccines: AST - VAC1, an autologous (patient - specific) vaccine based on cells sourced from the patient, and AST - VAC2, an allogeneic (non-patient specific) vaccine manufactured from our proprietary pluripotent stem cell platform.

They caution that a human UTI vaccine based on the approach is still years away.

Another significant achievement of TRANSVAC in its first funding period was to develop a roadmap to define a coherent and strategy - led approach to address the existing fragmentation of European vaccine development, based on the unification of leading European vaccine experts, so as to establish a «European vaccine R&D infrastructure».

There her research focused on inventing molecular, bead and array - based approaches to enable novel vaccine discovery against infectious and chronic diseases At the University of Texas Southwestern Medical she pursued technologies that became the basis of a Texas biotechnology company that was ultimately acquired by MacroGenics, Inc..

The Vaccine & Immunotherapy Center brings together many outstanding researchers within the Institute to focus on new immune based approaches to induce protective tumor immunity, to control the tumor microenvironment, and to use humoral and cellular immunity to control or eliminate cancer.

The Agrobacterium tumefaciens - based system is a robust platform to either rapidly produce up to mg - amounts of recombinant proteins or to compare larger numbers of different vaccine constructs in a screening approach preferentially by transient expression in N. benthamiana plants.

Furthermore, our transient plant - virus expression system could generate vaccines in less time than required with some animal cell - based approaches (31).