Sentences with phrase «based vaccines targeting»
We are developing dendritic cell - based vaccines targeting telomerase, a protein expressed in over 95 percent of cancers and rarely found in normal adult cells.
http://asteriasbiotherapeutics.com/ Not exact matches
Researchers at MedImmune, a Maryland - based biotech company, and at Washington University in St. Louis whipped up two separate vaccine formulations in the hope that at least one would successfully target an «adhesion» molecule called Filamentous H, or FimH, present on E. coli.
The Pasteur team says the finding could lead to the development of vaccines based on CD26 inhibitors or an antibody targeting either the V3 loop or CD26.
Childhood vaccines are recommended worldwide, based on their protective effect against the targeted diseases.
To be most effective, DNA vaccines need to be based on the genes of the viruses present in the target population, so regular genetic diversity monitoring is essential, Dukhovlinova says.
These same models are used to develop new anti-cancer vaccines based on long peptide or DNA vaccination targeting the antigen to antigen presenting cells.
«Each patient is different, so we're developing a personalized vaccine based on specific targets we identify on a patient's tumor,» Overman says.
As a part of VIOLIN, we have developed Vaxign, the first web - based publically available vaccine target design tool based on bioinformatics analysis of genome sequences using the strategy of reverse vaccinology.
The paper reports that it could potentially form the base for a new universal influenza vaccine that could target all strains of the virus.
A key program of VIOLIN is Vaxign, the first web - based publically available vaccine target design tool based on bioinformatics analysis of genome sequences using the strategy of reverse vaccinology.
Such antibodies are expected to reduce the efficacy of vaccines based on common human serotypes of adenovirus in a human target population.
«This loss - of - HLA mechanism suggests that, when designing vaccines and cell - based therapies, we need to target antigens that are presented to the immune system,» says Swanton.