Sentences with phrase «basewide hindlimb»

The carnivorous animal, which was roughly the size of a small lion, walked on all fours, its forelimbs and hindlimbs are similar in proportion, and the limbs themselves are pretty short relative to the length of the body.
Relative to the large and powerful hindlimbs, Tyrannosaurus forelimbs were small and retained only two digits.
Mice showing hindlimb paralysis were able to regain motor function within two weeks after KPT - 276 or KPT - 350 were orally administered.
Archicebus achilles had long hindlimbs and short forelimbs, typical of such an animal.
Its hindlimbs, they argued, had evolved for efficient, powerful swimming.
Chief among the criticisms were the animal's hindlimbs, significantly smaller compared with other large predatory dinosaurs, as well as other researchers» theoretical Spinosaurus models.
But this does not square with its slender pelvis and long slender hindlimbs.
The creature's hindlimbs were reduced in size, another adaptation for life at sea.
The tail is very capable in this leglike role: While contributing little braking force, the tails provided more forward - moving force than both the animals» forelimbs and hindlimbs combined, the team reports online today in Biology Letters.
Only later, in the Middle Miocen epoch, did whales reach the modern condition of having no external vestigial hindlimbs.
Meanwhile, the same digits in the mouse continued at their slower rate, as did the bat's hindlimb digits.
The chitosan gel resembles the alginate material used to encapsulate cells by the Taylor lab. Yoon's team was testing efficacy in a hindlimb ischemia model, in which a mouseâ $ ™ s leg is deprived of blood.
Mutant mice exhibited craniofacial malformations, hypopigmentation, intestinal pseudo-obstruction and hindlimb paralysis.
Lobe - finned ancestors of the lungfishes as well as tetrapods could have evolved hindlimb propulsion and the ability to walk on the substrate at the bottom of a lake or marsh millions of years before limbs with digits and land - dwelling animals appeared.
Motor dysfunction was evaluated in mThy1 - AS mice using a modification of the established «coat hanger test:» [17] animals were assessed for time to fall when holding on to a suspended vertical metal bar, with additional scoring for the ability to use the hindlimbs to assist (zero, one, or both hindlimbs engaged).
Though the forelimbs look similar to the hindlimbs, they were not involved in locomotion, the authors found.
mThy1 - AS controls were unable to recruit even one hindlimb to prevent their own falling, but AFF 1 treatment maintained such engagement to half of WT control animals» levels (average ≈ 1.0 vs. ≈ 1.75 hindlimbs engaged — all Figure 2).
[15] AFF 1 vaccination preserved sufficient functionality to allow treated model PD mice to cling on for 19 s. Hindlimb engagement is by analogy a, particularly suggestive outcome for animal models of a disease of fine motor control impairment.
Hindlimb bones were excised, fixed in 10 % neutral - buffered formalin, and imaged using a μCT scanner (SkyScan 1176, Bruker Corp.) at 17 - μm resolution and 180 ° scanning with a rotation step of 0.7 ° per image, 242 - ms exposure time, 55 - kV photon energy, and 455 - μA current.
Decreased metastasis by ABL - deficient breast cancer cells was accompanied by a significant reduction in the extent of hindlimb osteolytic lesions, as determined by x-ray and micro — computed tomography (μCT) imaging (Fig. 2, I and J).
Hindlimb bones were excised, fixed in 10 % neutral - buffered formalin, decalcified, and embedded in paraffin for H&E staining (28).
After injection of bone marrow - derived MSCs (BM - MSCs) into hindlimb muscles, NCVs were restored to near - normal levels.
Paracrine or proangiogenic effects of implanted early rECs played a significant role in repairing hindlimb ischemia.
While early rECs exhibited an immature phenotype, their implantation into ischemic hindlimbs induced enhanced recovery from ischemia.
It's the opposite of a hindlimb.
Interestingly, though, the postcranial remains from Dmanisi are more primitive (more similar to earlier species; e.g., the hindlimb was relatively longer) than those found at many other sites.
In this study in rats, a «synergist ablation» overload model was used, where the gastroc and soleus muscles on the right hindlimb were surgically removed, overloading and activating growth in the plantaris muscle.
Injection of the IGF - 1 gene therapy into both quadriceps (upper hindlimb) muscles and into muscles between the ribs that help control breathing maintained strength and lengthened survival.
This most commonly happens where the hindlimb gets caught in a fence whilst jumping.
This causes substantial problems walking as both hindlimbs are painful and it is not uncommon for the symptoms to be mistakenly attributed to a spinal cord injury.
There is typically a hindlimb lameness that varies from mild to non-weight bearing.
Patellar luxation (PL) is one of the most common hindlimb orthopedic pathologies seen in dogs and has been diagnosed in many other mammalian species as well.
Overall hindlimb strengthening can be accomplished by the following exercises (FIGURES 3 and 4):
Patellar luxation is one of the most common hindlimb orthopedic abnormalities seen in dogs.
Dogs presenting with grade II or III luxation usually have a history of occasional skipping, intermittent or consistent hindlimb lameness, and reluctance to jump or walk down a slope.
Many cats will resist and float their hindlimbs or try climbing out of the treadmill at higher water levels.
For 3 to 8 weeks after surgery, therapeutic exercises will continue to be added and modified, with the goals of maintaining or gaining normal ROM of the stifle, increasing weightbearing of the surgical limb, and building muscle strength of the hindlimbs and core stabilizers.
It can cause acute pain and various clinical signs such as loss of function of the hindlimbs (most commonly, although other organs or limbs can be affected).
A cat that is having difficulty breathing from heart failure or has loss of function of hindlimbs or front limbs, requires veterinary care as quickly as possible.
Some severe cases may have other neurological deficits such as fore and hindlimb limb weakness and ataxia (wobbliness).
On presentation, the horse was ataxic and exhibited hindlimb weakness.
A consequence of this was that he scratched in the air with one hindlimb whilst walking.
Diagnostics and Exam Findings: Diagnosed with acute bilateral and biaxial desmitis / degeneration of all four hindlimb suspensory branches after clinical examination, diagnostic analgesia, ultrasonography and radiography.
In severe cases the hindlimbs may become paralyzed
Large toys for self - play can be useful to encourage the elderly cat to grab and kick, giving important «range of movement» exercise for stiff hindlimbs (FIGURE 2).
The usual symptom is intermittent lameness in a forelimb or hindlimb without any known trauma or injury.
Vaccination - site guidelines recommend administration of rabies in distal portion of right hindlimb, FeLV in distal portion of left hindlimb, and all other vaccines in right shoulder region.
The most common symptom is a sudden «toe - touching» lameness in one of a dog's hindlimbs.
A veterinary surgeon once told me that a hindlimb lameness in a middle - aged to older dog is a torn cruciate until proven otherwise.
The most obvious abnormality in these dogs is a basewide hindlimb stance and gait.
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