- NIA also sponsors five Nathan Shock Centers of Excellence that focus on
the basic biology of aging:
Not exact matches
Included are talks on mechanisms
of aging in a wide range
of established and non-traditional animal models with the key objective to enhance understanding
of the
basic biology behind experimental and lifestyle manipulations thought to have direct translational application to human
aging.
Since its founding in 1965 the Glenn Foundation for Medical Research («GFMR») has supported
basic research to better understand the
biology that governs normal human
aging and its related physiological decline, with the objective
of developing interventions that will extend the healthy years
of human life.
In the summer
of 2010, we posted an entry about a significant advance in
basic mitochondrial
biology that held within it a tantalizing promise: a potentially new approach to obviating the problem
of age - related accumulation
of mutations in mitochondrial DNA (mtDNA), which are widely suspected to play an important role in the
age - related rise in oxidative stress, Parkinson's disease, and
age - related muscle degeneration.
As one
of the three initial cores established when the Buck Institute was founded, the Genomics Core has played a vital role in helping shape investigations in the
basic molecular
biology of aging, from assisting in the investigation
of how specific drugs can extend lifespan in simple model organisms such as the nematode C. elegans, to facilitating studies in various animal models
of age - related disease.
«The idea was to continue studying the
basic biology of lysosomes and the changes as we
age.»
I believe that many venues
of science, from
basic physiology to the
biology and genetics
of aging point to a simple, but very powerful statement concerning health, that I have stated for many years and has yet to be disproven.