Sentences with phrase «basic mechanisms of cancer»

Not exact matches

«This novel technique,» they said, «should help distinguish and monitor cancer stages and progression, aid in elucidation of basic mechanisms underlying tumorigenesis, and facilitate analyses of processes related to early detection of cancer, screening and / or cancer risk assessment.»

The research, published in the Journal of Cancer Survivorship, also adds to the basic understanding of the pathophysiology of traumatic stress in general and the underlying mechanisms involved with resolving it.

Understanding the physiological mechanisms that cause or, as in this case, prevent genetic instability is a basic question in Molecular Biology and Biomedicine which is of vital importance in the research against cancer, given that genetic instability is a distinctive feature of tumorous cells.

Basic research on cancer mechanisms has led to over 40 targeted cancer therapies currently on the market, which take the form of monoclonal antibodies, small molecule drugs, and immunotherapies.

Kathleen Kelly, a cancer biologist at NCI, is optimistic that the work will enhance understanding of the basic mechanism of the disease.

In particular, he wanted to study the genomes of marbled crayfish to uncover basic mechanisms underlying epigenetics, the binding of molecules to DNA that can drive tumor growth and help cancer spread.

«This is a significant example of how knowing details of potential mechanisms and the basic science of redox active compounds in cancer versus normal cells can be leveraged clinically in cancer therapy,» says co-senior author Douglas Spitz, who focused on the biochemical studies.

Over the years, Dr. Nimer has conducted extensive clinical and basic science research into the treatment and genetic basis of adult leukemia and bone marrow failure states, defining the regulatory mechanisms that control the production of blood cells and exploring ways to improve the treatment of blood based cancers.

An area of long - standing and exceptional strength of the Cancer Center is basic science discovery into novel cancer gene targets and their mechaCancer Center is basic science discovery into novel cancer gene targets and their mechacancer gene targets and their mechanisms.

Klemke, Wang, and their colleagues are involved in research on aspects of the basic biology behind metastasis — trying to identify the signal transduction mechanisms that lead to the spread of breast cancer cells.

Research in the Immunology, Microenvironment and Metastasis program is aimed at 1) merging basic mechanistic understanding of multidisciplinary pathways of host - tumor interactions and metastatic dissemination with novel translational opportunities for diseases diagnosis and immunotherapy, as well as 2) investigating mechanisms regulating immune responses in cancer and their potential therapeutic manipulation.

Moreover, PHENONIM - ICS is involved in European projects presenting a strong impact on human health: Interreg CARDIOGENE (Genetic mechanisms of cardiovascular diseases), GENCODYS (Genetic and epigenetic networks involved in cognitive dysfunctions), AgedBrainSYSBIO (Basic studies of brain aging), as well as projects in partnership with industry: MAGenTA (an Industrial Strategic Innovation project supported by Bpifrance about the treatment of major urogenital diseases) and CanPathPro (H2020 program), to develop a predictive modeling platform of signaling pathways involved in cancers.

All CM members have research interests in basic cancer mechanisms, including the normal functions of oncogenes and tumor suppressor genes; regulators of cell cycle and apoptosis; regulators of angiogenesis and metastasis; and stem cells and blood formation.