Sentences with phrase «basic molecular studies»

Research in the Leukemia Program spans from direction of clinical trials to basic molecular studies of leukemia biology, immunotherapy and development of novel agents, and to mitigating the late effects of treatment in long - term survivors.

Not exact matches

The fields within biology are further divided based on the scale at which organisms are studied and the methods used to study them: biochemistry examines the fundamental chemistry of life; molecular biology studies the complex interactions of systems of biological molecules; cellular biology examines the basic building block of all life, the cell; physiology examines the physical and chemical functions of the tissues and organ systems of an organism; and ecology examines how various organisms interrelate.

«Our results demonstrate that if we find the right molecular context, more appropriate therapies can be chosen that improve outcomes,» says John Carpten, Ph.D., TGen deputy director of basic science and director of TGen's Integrated Cancer Genomics Division, and the study's senior author.

«These findings are the result of years of NHLBI - funded studies of the molecular mechanisms of action of GPIHBP1 and are an excellent example of how basic science can lead to scientific advances with direct clinical implications.»

The study, published in the journal eLife, provides a valuable model for uncovering the basic molecular mechanisms governing the interplay of immunity and regeneration, and could point the way toward new therapies to combat serious human ailments like chronic non-healing wounds.

Lydia Villa - Komaroff, a molecular and cellular biologist and co-founding member of the Society for the Advancement of Chicanos / Hispanics and Native Americans in Science, underscored the value of basic research, noting that her work studying strains of infection - resistant bacteria led to a discovery that «made it possible to make insulin and other treatments in bacteria.

The basic lines of his current work are three: in the first place, the study of evolutionary relations within aphids as well as the evolution of their life cycles; in the second place, the molecular bases that control the seasonal and circadian rhythms in aphids (and in insects in general) and their relation to vital cycles; and finally, myrmecophily in aphids, recently included.

His current research uses a variety of molecular, biochemical, and genetic approaches to study the basic biology of mesenchymal stem cells (MSCs).

«Although this is basic scientific research using animal models, these studies are shedding light on the molecular mechanisms that control male fertility, and are helping us to better understand the causes of many cases of infertility and enabling new horizons to be opened up in the development of therapeutic targets and strategies to combat it,» explained Dr Subirán.

Gerald Späth, Director of the Molecular Parasitology and Signaling Unit at the Institut Pasteur in Paris, who directed the experimental part of this study, comments: «Basic, applied, and clinical research in Leishmania is nearly exclusively conducted using parasites from long - term culture.

Of the two available models, a dual - degree program is probably the best approach for students interested in basic science, because the choices available for research training are likely to be wider and include more opportunities for basic science and bench research into molecular mechanisms, compared to graduate programs or postdoctoral fellowships linked to post-MD clinical training; the latter is more likely to be focused more on clinic - based studies.

A few species are studied as model organisms that can be used to gain knowledge of basic processes such as genetics, physiology, biochemistry, and molecular biology with results that are applicable to many organisms (Taylor et al., 1993).

The aim of the Interdisciplinary Training in Cancer Research training program is to train young scientists to design and conduct research on significant problems in cancer by combining information and approaches from different scientific disciplines, including basic cellular and molecular biology, epidemiology, clinical trials and studies, and behavioral - social sciences.

In situ atomic force microscopy studies and molecular dynamics simulations were supported by the U.S. Department of Energy (DOE), Office of Science, Office of Basic Energy Sciences, Biomolecular Materials Program at PNNL.

The authors stressed that their findings, which combine basic science with large - scale analysis of genetic studies, depended on an unusual level of cooperation among experts in genetics, molecular biology, developmental neurobiology and immunology.

In basic research, xenopus is used for studies in development biology, cell biology, molecular genetic and in the area of ecotoxicology.

The scope of the journal encompasses all of «traditional» molecular biology (including DNA replication, recombination and repair, gene expression, RNA processing, translation, and protein folding, modification, and degradation) as well as studies of the molecular interactions and mechanisms that underlie basic cellular processes.

This work is part of ongoing studies at the Center for Molecular Electrocatalysis, a DOE Office of Science, Office of Basic Energy Sciences, Energy Frontier Research Center.

Research ranges from basic molecular and genetic studies to epidemiological and clinical research on cancer prevention, early diagnosis, molecular characteristics of the cancer process and new treatments for cancer using drugs and radiotherapy.

As one of the three initial cores established when the Buck Institute was founded, the Genomics Core has played a vital role in helping shape investigations in the basic molecular biology of aging, from assisting in the investigation of how specific drugs can extend lifespan in simple model organisms such as the nematode C. elegans, to facilitating studies in various animal models of age - related disease.

«This was a truly translational project, bringing together researchers from both basic and clinical sciences to study the molecular mechanisms underlying disease,» Rajarathnam said.

The RegMed Track links basic molecular and cellular research with translational and clinical studies, and includes stem cell biology, molecular medicine, regenerative biology and translational research.

James L. Manley, Ph.D., a molecular biologist and Julian Clarence Levi Professor of Life Sciences in the Department of Biological Sciences at Columbia University is studying, together with his colleague Tsuyoshi Kashima, M.D., the basic biology of the SMN gene to find ways in which to recover its activity in patients.