Translational research is about translating
basic research findings into medical practice to improve health outcomes.
The CRS4's Bioinformatics laboratory has access to large clinical sample sets and genomic data and closely collaborates with hospitals to support clinical researchers in translating
basic research findings into clinical applications.
As the center's director, Huang aims to accelerate the conversion of
basic research findings into efficient clinical candidates and, ultimately, medical applications.
The center aims to accelerate the conversion of
basic research findings into efficient clinical candidates and, ultimately, medical applications.
Not exact matches
Without delving
into quarterly reports and other figures that might otherwise overwhelm a new dividend investor I have
found that sticking to some
basic ideas for choosing stocks can be as effective as the mountains of
research others tend to do.
Another area that is becoming increasingly important is the translation of
basic science
research findings into clinical applications, and there is a growing need for physician scientists, says Alan Trounson, president of the California Institute for Regenerative Medicine (CIRM).
Some
basic research findings are being translated
into new treatments, and with the discovery of induced pluripotent stem cells in 2006, the field has seen a step - change in biological understanding that will affect the way new drugs are identified and tested and, potentially, the way cells can be generated in the lab.
That
basic grounding could help teachers assess the importance of new
research and
find ways to incorporate it
into their classrooms.
Similarly, disease - specific fluorescence markers are
finding their way back
into basic research in high content screening applications.
In order to obtain the comprehensive designation, which is the highest ranking the National Cancer Institute (NCI) gives, a center must meet strict criteria that include a strong core of
basic laboratory
research in several fields, the ability to translate those
research findings into therapies that can one day be used to treat patients, a program of high - priority clinical trials, and a commitment to community service and outreach activities related to cancer prevention and control.
«By integrating
basic research with work on patients, she helped to transfer her
findings into the clinical routine,» Annette Peters comments on Karen Nelson's achievements.
The aim of our
research is to expand
basic knowledge of the disease and to translate these and other
basic findings into therapeutic applications in the clinic.
She leads a
research group that follows two distinct but complementary approaches:
basic science focusing on cellular mechanisms of neurodegeneration, and a programme to translate those
findings into treatments and cures.
As teams at the institute for translational science work to turn
basic science
findings into treatments for real patients, they can also identify new and important unresolved questions in medicine and population health and make them
research priorities in the lab.
The next step in this ongoing
research project involved translating the
findings from
basic research into applied clinical
research with experimental treatment of human cancer patients.
In rodents, ketogenic diets reduce reactive oxygen species in the brain34 and reduce central inflammation and reactive oxygen species in a model of multiple sclerosis.35 Two clinical papers have
found that ketogenic diet feeding of 12 weeks to 6 months reduced signs of liver inflammation in obese patients with nonalcoholic fatty liver disease (in addition to improving various other physiological and biochemical variables).36, 37 Unfortunately,
basic research into non-alcoholic fatty liver disease has been hampered by species differences between mice and humans in their hepatic reaction to ketogenic diets.38
It remains extremely rare for the
findings of
basic research to be developed
into clinical applications, and it takes a long time for the process to be achieved.
The task of advancing the development of
basic research into clinical reality lies with translational science, yet the field seems to struggle to
find a way to move forward.
Instead of regurgitating a list of
basic facts that anyone could
find out through a Google search, go deeper
into your
research — look at the company press releases, Glassdoor listings and LinkedIn postings to read between the lines of what past and former employees have to say.
This
finding replicates past
research and reinforces numerous calls in the literature (Coley, 2001; Marsiglio, Amato, Day, & Lamb, 2000) to move the study of father involvement past the
basic level of presence / absence
into more detailed investigations.»