Peptide nucleic acid, a synthetic hybrid of protein and DNA, could form
the basis of a new class of drugs — and of artificial life unlike anything found in nature
Not exact matches
(Reuters)- Alnylam Pharmaceuticals Inc's RNAi -
based drug that targets a rare genetic disease met the main goal
of a key study, in a breakthrough for the
new class of medicines that works by blocking disease - causing proteins.
In the late 1990s — with the advent
of a
new class of protein -
based drugs, monoclonal antibodies — demand sometimes outstripped supply.
The resulting «map»
of gene -
drug interactions allowed the researchers to accurately predict the responses
of multiple human cancer cell lines to different chemotherapy agents
based on the cell lines» genetic profiles and also revealed
new genetic factors that appear to determine the response
of breast and ovarian tumor cells to common
classes of chemotherapy treatment.
«Now you have a way to test efficacy
of future vaccines or future therapeutics, whether those therapeutics are
drugs that exist already that could be used in a different way for a different purpose, or
new classes of drugs such as antibody -
based therapeutics that would be more specifically against Zika,» Diamond said.