Sentences with phrase «basis of model results»

There is an important methodological point here — distrust conclusions reached primarily on the basis of model results.

Not exact matches

He said that his research should not be called «modeling» because it is based on the combined findings of thousands of lab results, as well as several other studies he has published.

The machine - learning - based model by Medial EarlySign used data found in EHRs, such as laboratory tests results, demographics, medication, and diagnostic codes, to predict a patient's risk of experiencing renal dysfunction.

I believe this is the result of our unique, actively - managed quant models and nimbleness to act based on market volatility, money flows and other factors.

The current impasse between the Parliamentary Budget Officer and the Government is the result of a clash between the Government's business model, based on a lack of transparency, and accountability; non-evidenced based decision - making; and hostility to public debate and discussion; and, a Parliamentary Budget Officer business model with the exact opposite principles.

Based on energy consumption in Model S of 181 Wh / km, this results in 90 g CO2 / km.

Their job is less labor intensive; they buy and sell every day based strictly on the results of their computer model.

Time for some brutal honesty... this team, as it stands, is in no better position to compete next season than they were 12 months ago, minus the fact that some fans have been easily snowed by the acquisition of Lacazette, the free transfer LB and the release of Sanogo... if you look at the facts carefully you will see a team that still has far more questions than answers... to better show what I mean by this statement I will briefly discuss the current state of affairs on a position - by - position basis... in goal we have 4 potential candidates, but in reality we have only 1 option with any real future and somehow he's the only one we have actively tried to get rid of for years because he and his father were a little too involved on social media and he got caught smoking (funny how people still defend Wiltshire under the same and far worse circumstances)... you would think we would want to keep any goaltender that Juventus had interest in, as they seem to have a pretty good history when it comes to that position... as far as the defenders on our current roster there are only a few individuals whom have the skill and / or youth worthy of our time and / or investment, as such we should get rid of anyone who doesn't meet those simple requirements, which means we should get rid of DeBouchy, Gibbs, Gabriel, Mertz and loan out Chambers to see if last seasons foray with Middlesborough was an anomaly or a prediction of things to come... some fans have lamented wildly about the return of Mertz to the starting lineup due to his FA Cup performance but these sort of pie in the sky meanderings are indicative of what's wrong with this club and it's wishy - washy fan - base... in addition to these moves the club should aggressively pursue the acquisition of dominant and mobile CB to stabilize an all too fragile defensive group that has self - destructed on numerous occasions over the past 5 seasons... moving forward and building on our need to re-establish our once dominant presence throughout the middle of the park we need to target a CDM then do whatever it takes to get that player into the fold without any of the usual nickel and diming we have become famous for (this kind of ruthless haggling has cost us numerous special players and certainly can't help make the player in question feel good about the way their future potential employer feels about them)... in order for us to become dominant again we need to be strong up the middle again from Goalkeeper to CB to DM to ACM to striker, like we did in our most glorious years before and during Wenger's reign... with this in mind, if we want Ozil to be that dominant attacking midfielder we can't keep leaving him exposed to constant ridicule about his lack of defensive prowess and provide him with the proper players in the final third... he was never a good defensive player in Real or with the German National squad and they certainly didn't suffer as a result of his presence on the pitch... as for the rest of the midfield the blame falls squarely in the hands of Wenger and Gazidis, the fact that Ramsey, Ox, Sanchez and even Ozil were allowed to regularly start when none of the aforementioned had more than a year left under contract is criminal for a club of this size and financial might... the fact that we could find money for Walcott and Xhaka, who weren't even guaranteed starters, means that our whole business model needs a complete overhaul... for me it's time to get rid of some serious deadweight, even if it means selling them below what you believe their market value is just to simply right this ship and change the stagnant culture that currently exists... this means saying goodbye to Wiltshire, Elneny, Carzola, Walcott and Ramsey... everyone, minus Elneny, have spent just as much time on the training table as on the field of play, which would be manageable if they weren't so inconsistent from a performance standpoint (excluding Carzola, who is like the recent version of Rosicky — too bad, both will be deeply missed)... in their places we need to bring in some proven performers with no history of injuries... up front, although I do like the possibilities that a player like Lacazette presents, the fact that we had to wait so many years to acquire some true quality at the striker position falls once again squarely at the feet of Wenger... this issue highlights the ultimate scam being perpetrated by this club since the arrival of Kroenke: pretend your a small market club when it comes to making purchases but milk your fans like a big market club when it comes to ticket prices and merchandising... I believe the reason why Wenger hasn't pursued someone of Henry's quality, minus a fairly inexpensive RVP, was that he knew that they would demand players of a similar ilk to be brought on board and that wasn't possible when the business model was that of a «selling» club... does it really make sense that we could only make a cheeky bid for Suarez, or that we couldn't get Higuain over the line when he was being offered up for half the price he eventually went to Juve for, or that we've only paid any interest to strikers who were clearly not going to press their current teams to let them go to Arsenal like Benzema or Cavani... just part of the facade that finally came crashing down when Sanchez finally called their bluff... the fact remains that no one wants to win more than Sanchez, including Wenger, and although I don't agree with everything that he has done off the field, I would much rather have Alexis front and center than a manager who has clearly bought into the Kroenke model in large part due to the fact that his enormous ego suggests that only he could accomplish great things without breaking the bank... unfortunately that isn't possible anymore as the game has changed quite dramatically in the last 15 years, which has left a largely complacent and complicit Wenger on the outside looking in... so don't blame those players who demanded more and were left wanting... don't blame those fans who have tried desperately to raise awareness for several years when cracks began to appear... place the blame at the feet of those who were well aware all along of the potential pitfalls of just such a plan but continued to follow it even when it was no longer a financial necessity, like it ever really was...

To assess the robustness of the results of our regression analysis, we performed covariate adjustment with derived propensity scores to calculate the absolute risk difference (details are provided in the Supplementary Appendix, available with the full text of this article at NEJM.org).14, 15 To calculate the adjusted absolute risk difference, we used predictive margins and G - computation (i.e., regression - model — based outcome prediction in both exposure settings: planned in - hospital and planned out - of - hospital birth).16, 17 Finally, we conducted post hoc analyses to assess associations between planned out - of - hospital birth and outcomes (cesarean delivery and a composite of perinatal morbidity and mortality), which were stratified according to parity, maternal age, maternal education, and risk level.

Although not directly comparable, our findings are in broad agreement with those from routine data in Scotland that have indicated a positive association between Baby Friendly accreditation, but not certification, and breastfeeding at 1 week of age.17 Our findings reinforce those of Coutinho and colleagues who reported that high exclusive breastfeeding rates achieved in Brazilian hospitals implementing staff training with the course content of the Baby Friendly Hospital Initiative were short - lived and not sustained at home unless implemented in combination with post-natal home visits.35 Similarly in Italy, training of staff with an adapted version of the Baby Friendly course content resulted in high breastfeeding rates at discharge, with a rapid decrease in the days after leaving hospital.36 In contrast, a cluster randomized trial in Belarus (PROBIT) found an association between an intervention modelled on the Baby Friendly Initiative with an increased duration of breastfeeding37 an association also reported from an observational study in Germany.38 Mothers in Belarus stay in hospital post-partum for 6 — 7 days, and in Germany for 5 days, with post-natal support likely to be particularly important in countries where mothers stay in the hospital for a shorter time, with early discharge likely to limit the influence of a hospital - based intervention.

Meta - analyses of this expanded research base confirm the model's impacts on a range of risk and protective factors associated with child maltreatment.7, 8,9 In addition, all of the major home visitation models in the U.S. are currently engaged in a variety of research activities, many of which are resulting in better defined models and more rigorous attention to the key issue of participant enrolment and retention, staff training and quality assurance standards.10 For example, recent findings emerging from the initial two - year follow - up of the Early Head Start National Demonstration Project confirm the efficacy of home visitation programs with new parents.

Processing the biological data at the deepest level, such as DNA base pairs, therefore only makes sense if this analysis can used to build models of biological processes and if the resulting predictions can be tested.

Random fluctuations and three physical reasons come into question to explain this: The model calculations are based on different amounts of radiant energy from the sun that impinge on Earth's surface and are stored as a result of the greenhouse effect, e.g. due to atmospheric carbon dioxide.

Based on modeling results by the National Oceanic and Atmospheric Administration (NOAA), which predicted that Pacific Ocean temperatures would rise by 1 degree Celsius (2 degrees Fahrenheit) over the next 50 years, a Canadian and U.S. team of scientists examined the distributional changes of 28 species of fish including salmon, herring, certain species of sharks, anchovies, sardines and more northern fish like pollock.

The results are based on a number of independent climate archives, as well as instrumental records, and hold up whilst applying a wide range of correction methods, which leads Laepple to believe that the problem lies more with the models.

The model calculations, which are based on data from the CLOUD experiment, reveal that the cooling effects of clouds are 27 percent less than in climate simulations without this effect as a result of additional particles caused by human activity: Instead of a radiative effect of -0.82 W / m2 the outcome is only -0.60 W / m2.

«The study results elucidate the molecular mechanisms underlying disease progression in multiple sclerosis models, providing a basis for future clinical trials to determine safety and efficacy of these chemical agents in humans with demyelinating disorders,» says Patrizia Casaccia, MD, PhD, Professor of Neuroscience, Genetics and Genomic Sciences at Mount Sinai and senior author of the study.

«For the study, we chose a decision analysis design because we could use a mathematical model to simulate the outcomes and costs of each treatment path based on results and costs that have already been published in the literature,» Dr. Dodwell explained.

People who are open - minded are beginning to realise that the results of our paper are beautiful: simple mathematical models based on standard natural selection are sufficient to explain the evolution of eusociality or other phenomena in social evolution.

By comparing the results of agent - based models against real archeological evidence, anthropologists can identify past conditions and circumstances that led different civilizations around the world into periods of growth and decline.

«Our results reflect the importance of lifelong follow - up for individuals diagnosed as having MGUS, independent of risk score, and highlight the need for better risk models based on the biology of the disease.

Overall, the study results suggest that the dual comb technique is ideally suited to precise, reproducible sensing of trace gases in the atmosphere and can support the development of accurate models for use in global, satellite - based greenhouse gas monitoring.

«Our results are based on a realistic modelling of the accretion of gas onto the black holes, and of the radiation they emit, which is compatible with current astronomical observations.

Based on the results of that test, Beaty and colleagues developed a predictive model and tested against brain scan data collected for earlier studies on creativity.

Dozens of teams submitted 179 predictions based on state - of - the - art computational models, and the organisers compared them against the experimental results.

They also explained the experimental results with models based on the estimation of nanoscale interactions between the tiny building blocks.

Based on these results the researchers developed a unified model connecting all so far reported switching states to the behavior of oxygen vacancies.

They show that this new formulation reduces the minimal curative dose in a disease model, based on infections in mice, by 100-fold and, most importantly, circumvents drug resistance in a cell line that is resistant as a result of mutations in the transporter that mediates drug uptake.

Specifically, the authors argue that evaluation models should move away from output - focused to more results - based evaluation models, specifically in the context of the new millennium development goals.

«Based on these results and the model visualizations of the Bennett linkages, we can propose a new strategy for improving our control of Bennett linkages in large DNA scaffolds,» said Ren.

They are physics - based, and fault slip distribution and ground motion are calculated results of the models.»

«Our results are based on the expression of genes in two model organisms.

So far, these early results showed that physical conditions where the air and the ocean interact must be a vital part of any successful hurricane forecasting model and would help explain, and predict, how a storm might intensify as it moves through across the water based on the physical stress at the ocean's surface.

Fourches and Jeremy Ash, a graduate student in bioinformatics, decided to incorporate the results of molecular dynamics calculations — all - atom simulations of how a particular compound moves in the binding pocket of a protein — into prediction models based on machine learning.

During a briefing for the California Department of Food & Agriculture, scientists from the University of California, Davis, told officials that based on their preliminary research and modeling, the drought is resulting in a harder economic pinch this year than it was in 2014.

«Our results in experimental models of cancer suggest a new therapeutic strategy based on inhibiting the microRNA machinery — or the Let - 7 microRNAs — specifically in the TAMs, which may unleash the power of mainstream immunotherapies, such as immune checkpoint inhibitors.»

The results, published in the current issue of Human Molecular Genetics, open the door for pursuing gene editing in nonhuman primates as models for new therapies, including pharmacological, gene - and stem cell - based therapies, said Keith Latham, MSU animal science professor and lead author of the study.

Fourth, the observed autosomal divergence of gain and loss hotspot patterns in proximity to genes supports a model in which developmental / regulatory mechanisms (based on GO term results) are robust to large amounts of transposon driven DNA gain and loss.

However, in a subsequent analysis based on version 3 of the Hadley Model (HadCM3), Collins found that he could not detect a change in magnitude or frequency of ENSO as greenhouse gases increased, thus contradicting the results of his earlier study.

As Table S1 in my paper showed, there are differences even in the response to histGHG vs 1 % per year CO2 on the order of 10 %, so we would expect the TCR for each model to vary somewhat when computed based on a slightly different set of experiments, but even if the correct dT values and all forcings were included I don't believe the results would tell us anything useful.

Primary results of the work to date include development of a system dynamics model for risk perception based upon the theory of planned behavior.

For the earlier generation of models, results are based on the archived output from control runs (specifically, the first 30 years, in the case of temperature, and the first 20 years for the other fields), and for the recent generation models, results are based on the 20th - century simulations with climatological periods selected to correspond with observations.

The results of such models more closely match estimates based on real - world data.

Results: Today's climate models regard organic aerosols as static carbon - based molecules, but scientists at Pacific Northwest National Laboratory and the University of California, Irvine showed that the particles are very dynamic.

We also compare our results with the predictions of state - of - the - art population synthesis models based on the gravitational instability (GI) formation scenario by Forgan & Rice (2013), with and without scattering.

-- 7) Forest models for Montana that account for changes in both climate and resulting vegetation distribution and patterns; 8) Models that account for interactions and feedbacks in climate - related impacts to forests (e.g., changes in mortality from both direct increases in warming and increased fire risk as a result of warming); 9) Systems thinking and modeling regarding climate effects on understory vegetation and interactions with forest trees; 10) Discussion of climate effects on urban forests and impacts to cityscapes and livability; 11) Monitoring and time - series data to inform adaptive management efforts (i.e., to determine outcome of a management action and, based on that outcome, chart future course of action); 12) Detailed decision support systems to provide guidance for managing for adaptmodels for Montana that account for changes in both climate and resulting vegetation distribution and patterns; 8) Models that account for interactions and feedbacks in climate - related impacts to forests (e.g., changes in mortality from both direct increases in warming and increased fire risk as a result of warming); 9) Systems thinking and modeling regarding climate effects on understory vegetation and interactions with forest trees; 10) Discussion of climate effects on urban forests and impacts to cityscapes and livability; 11) Monitoring and time - series data to inform adaptive management efforts (i.e., to determine outcome of a management action and, based on that outcome, chart future course of action); 12) Detailed decision support systems to provide guidance for managing for adaptModels that account for interactions and feedbacks in climate - related impacts to forests (e.g., changes in mortality from both direct increases in warming and increased fire risk as a result of warming); 9) Systems thinking and modeling regarding climate effects on understory vegetation and interactions with forest trees; 10) Discussion of climate effects on urban forests and impacts to cityscapes and livability; 11) Monitoring and time - series data to inform adaptive management efforts (i.e., to determine outcome of a management action and, based on that outcome, chart future course of action); 12) Detailed decision support systems to provide guidance for managing for adaptation.

Laboratory tests of the activated SBMOF - 1, however, showed the material didn't behave as well as it should, based on the computer modeling results.

In both cases, the results are based on the same set of blastp searches, in which we blasted each Nasonia gene against the predicted proteomes of 30 additional species, including 12 additional Hymenoptera genomes, 6 Dipteran genomes, 5 additional insect genomes, 2 additional non-insect arthopod genomes, and 5 non-arthropod outgroup genomes (see Table S4 for the full list, including gene model versions and data sources).

Based on model experiments, it has been suggested that errors resulting from the highly inhomogeneous distribution of ocean observations in space and time (see Appendix 5.

The Finnish Meteorological Institute has participated in research to estimate, based on climate model results and measurements, the maximum amount of carbon dioxide that can be released into the atmosphere without passing the climate warming limits set by the Paris Climate Agreement.