Not exact matches
Immunotherapy is praised by
researchers because it is targeted, focusing on cancerous
cells rather than healthy tissue, as well as potentially durable.
Some
researchers have even looked at the chromosomes of the miscarried pregnancy to determine whether the NK
cells were elevated
because of the body's natural response to a chromosomally abnormal pregnancy.
Because of the rapidity with which it occurs (less than a tenth of a second) the
researchers argue that this influx is caused by micro-tears in
cell membranes ripped open by the force of the micro-explosion;
But
because women respond to medications and develop some diseases differently than men,
researchers need to include female lab animals, tissues and
cells in their experiments, according to a Nature commentary Clayton co-wrote in May.
Because its powerful technology can measure microstructural features in the brain, such as the diameter of nerve
cell axons, it enables
researchers to answer entirely new questions, says CUBRIC director Derek Jones.
Because of this limitation,
researchers have theorized that inherited methylation, also referred to as parental imprinting, largely remains stable throughout development, except during two important developmental milestones: after fertilization and during the creation of sperm and egg
cells.
Now,
researchers at Washington University School of Medicine in St. Louis have shown, in mice, that the virus infects a rare type of intestinal
cell called a tuft
cell, so named
because each
cell sports a cluster of hairlike extensions on its surface.
Now a team of
researchers has been able to identify accurately the sentinel node (SN) in head and neck squamous
cell carcinoma (HNSCC) using a novel tracer; a challenging task
because there are up to 150 different lymph nodes in the neck, and the differentiation of true SNs from secondary nodes is difficult.
Researchers in optogenetics can control genetically modified brain
cells using light but
because of these modifications, the technique is not yet deemed safe to use in humans.
Also,
researchers could carefully select which blood types to culture with each batch of stem
cells, creating stockpiles of needed blood products for people with extremely rare blood types whose blood
cell makeup makes it challenging to find good blood matches for transfusions
because they would reject most other types of blood.
Because the CAR - T
cells do not eradicate all cancer
cells, the
researchers think the immune therapy will need to be combined with other treatments.
This may still be speculative — Sherry agrees that it's not as though Sherley's grant was denied
because it went directly to an ES
cell researcher.
Because neural crest
cells contribute to so many tissues in the body, altering their function could change an animal's behavior, appearance and biology, the
researchers reasoned.
Because each
cell has its own unique mutation, when
researchers examine a pinch of skin or drop of blood containing millions of
cells, most mitochondrial mutations are hidden.
This basic fact makes it difficult for
researchers to discern the underlying mechanism of the disease: «It's very difficult to figure out what's wrong,
because the bone marrow is nearly empty of these
cells,» said Bessler, the director of CHOP's Pediatric and Adult Comprehensive Bone Marrow Failure Center.
According to
researchers, such margin guidelines are needed
because as many as two - thirds of the hundreds of thousands of suspicious skin moles removed each year in the United States require re-excision (further cutting out of mole
cells missed on the first attempt).
The
researchers used mice with skin like that of red - haired, fair - skinned people, who don't tan
because of a nonfunctioning protein on the surface of the skin
cells that make melanin.
Because HIF signals
cells to produce VEGF, the
researchers wondered whether deleting HIF in amacrine and horizontal
cells would also stop the pipeline of VEGF and normal intermediate layer blood vessel development.
That's in part
because researchers must properly align everything from motor proteins within
cells on the nanoscale to much larger muscle fibers and bundles of fibers on the centimeter scale.
That's probably
because, as
researchers at Tel Aviv University revealed, nanostructures in the insect's exoskeleton form a kind of solar
cell, harvesting light energy that could power the hornet's work.
But
researchers have found a mutation in a mouse gene that leads to an arthritis - like condition
because it causes the joint's cartilage
cells to pump insufficient amounts of pyrophosphate — a natural water softener — into the joint cleft.
Because the amino acids are «noncanonical,» they are effective tags that help
researchers identify proteins being synthesized in a
cell.
Previously, in mammalian
cells, other
researchers had discovered that when you mutate a specific modifying enzyme, the result is death
because the
cells can't replicate.
The virus can not infect noncancerous
cells, Kirn explained,
because researchers deleted its thymidine kinase gene, which it needs to replicate in the body.
A few years ago, MS
researchers were focused on a new type of immune
cell called the Th - 17
cell, which appeared to be a key player in driving the neuronal damage in MS.
Because Th - 17
cells produce the cytokine IL - 17,
researchers likewise thought this chemical was essential to the disease.
Most
researchers assumed that this is
because a few rogue cancer
cells find ways to circumvent the drugs before the whole tumour has been killed off.
It's more efficient than previous devices, the
researchers say,
because its two
cells absorb more light than single - layer solar devices,
because it uses light from a wider portion of the solar spectrum, and
because it incorporates a layer of novel materials between the two
cells to reduce energy loss.
Collins said that
because Hydra is such a simple animal and
because it is able to regenerate after complete dissociation into individual
cells, it offers
researchers the opportunity to use similar techniques as the ones employed in their experiments to examine how an organism develops from an unstructured group of
cells into a complex body plan.
The c - MYC pathway appeared to some
researchers to be an unlikely therapeutic target for beta
cell regeneration
because past studies had found it to cause beta
cell death when activated in high doses.
But when
researchers injected Anas platyrhynchos ducklings at 4, 9, or 14 weeks old with red blood
cells from sheep to simulate a parasitic infection, the birds — as adults — explored new items in their environment and approached small orange toys, a color they typically avoid
because they seem to associate it with toxic food.
Because this approach jams the host
cell machinery rather than directly attacking the bacteria, the chances of bacteria developing resistance could be very low, say the
researchers.
Because these organisms are excellent models for understanding stem
cell biology,
researchers were able to shed light on the earliest stages of follicle
cell differentiation, a previously poorly understood area of developmental biology.
Inpart that's
because in order to study the centromere's functions,
researchers have had to use techniques that kill the
cell.
Because calcium imaging is widely used to identify
cells in tissues throughout the body,
researchers studying other systems will be able to benefit from the published methodology.
To see if PGD and the pentose phosphate pathway were tied to the epigenetic changes the
researchers had detected in distant metastases, they treated tumor
cells from different sites in a single patient with the drug 6 - aminonicotinamide (6AN), which is known to inhibit PGD but is not used in humans
because of its severe side effects.
Because the MS4A proteins are expressed on many
cells in the body, the
researchers will also test whether they detect cues that are generated by the body itself.
«
Because of the Harvard Stem
Cell Institute, we were able to work with other
researchers to make patient
cells into any type of neuron,» said Young - Pearse, whose lab spent two years fine - tuning protocols with collaborators to generate the neurons needed for her early onset Alzheimer's study.
Researchers have turned their attention to these
cells because some of the sugar and fat they burn is stored in the body and might otherwise lead to increases in white fat, the form that increases in obesity.
Previous work by the
researchers developed plasma - activated
cell culture medium as a form of chemotherapy, but selected Ringer's solution in the present work
because of its simpler composition and likelihood of forming less complex reaction products.
The
researchers worked with Mycoplasma mycoides (a microbe that infects goats)
because it has one of the smallest genetic blueprints of any known self - replicating organism and lacks
cell walls, making it easier to insert new DNA.
Solar
cells based on cadmium and tellurium could move closer to theoretical levels of efficiency
because of some sleuthing by
researchers at the Department of Energy's Oak Ridge National Laboratory.
Because the random puffs of air were unexpected stimuli for the mice, the
researchers could directly compare the differences between legitimate and spontaneous signals in the eyelid - related Purkinje
cells that made the mice blink.
Because HIV uses CD4 to infect
cells, the
researchers used a CAR molecule that hijacks the essential interaction between HIV and the
cell surface molecule CD4 to make stem
cell - derived T -
cells target infected
cells.
Because many different types of
cells are active in the liver, the
researchers now want to populate the reactor with various combinations of
cells.
People whose
cells make too much alpha - synuclein or make a mutated form of the protein are at high risk of developing PD
because of the protein's toxicity,
researchers found.
They do not yet form the basis for a therapy,
researchers said,
because methods must still be perfected to get them more selectively into the cancer
cells.
The
researchers hypothesize that guanabenz stimulates a protective cascade —
because fewer oligodendrocytes die, less immune
cells are recruited to the brain, which results in a decreased inflammatory response and preservation of myelin levels.
The
researchers could tell that a single virus had travelled over more than one
cell because some viruses which left a
cell with an uncoloured actin tail picked up a red actin tail from another
cell.
The
researchers say such «hypopigmentation» occurs
because chloroquine poisons pigment - producing
cells in hair follicles.
Researchers have printed with live
cells before, but until now they only made tiny pieces of gelatinous living material, both
because large structures tended to collapse and
because the
cells inside tended to die from lack of oxygen.