Not exact matches
This is
because the immune system is so depleted at this point that it can not make adequate
antibodies to fight the disease, hence there are no
antibodies circulating in the bloodstream for the test to detect.
perhaps
because that dog's immune system is producing large amounts of anti-heartworm
antibody that ties up the heartworm protein fragments that normally
circulate in the pet's blood stream — but, if something like that can actually occur, it is quite rare
Any dog that has such
antibodies circulating in the bloodstream, could potentially develop thyroid disease, and / or be vulnerable to other autoimmune diseases
because his or her immune system is compromised.
Puppies whose mothers have been routinely vaccinated are also less commonly and less seriously affected,
because vaccination of the dam boosts
circulating maternal
antibody levels in her young puppies.
The ELISA test is considered not as accurate
because many dogs without atopy are tested positive, which may happen when the dog has been exposed to the allergen and has developed
circulating antibodies against it.