The imperfect - vaccine hypothesis attracted controversy [11 — 14], not least
because human vaccines have apparently not caused an increase in the virulence of their target pathogens.
Not exact matches
Another factor is use of the
human papillomavirus (HPV)
vaccine,
because HPV is a root cause of most cervical cancers.
Because there is no
vaccine for
humans, efforts to curb the disease's spread focus on controlling mosquitoes and their infection rates.
The multi-author study, by the Global Alliance for Rabies Control's Partners for Rabies Prevention Group, also shows that annual economic losses
because of the disease are around 8.6 billion US dollars, mostly due to premature deaths, but also
because of spending on
human vaccines, lost income for victims of animal bites and other costs.
For example, although early clinical trials of Listeria - based
vaccines have shown that the neutralized bacterium produces only mild flulike symptoms in
human patients with cervical cancer, the various methods of genetically disarming the bacteria should be explored to find the safest approach for people gravely ill with pancreatic cancer,
because these patients are likely to already have weak immune systems.
«The quality of these naturally occurring
human antibodies as biological drugs to treat the virus infection is remarkable, and we are doubly encouraged
because they recognize multiple species of Ebola,» said immunologist James Crowe, Director of the Vanderbilt
Vaccine Center.
Human safety tests of two
vaccines began in the summer of 2014, after the prototypes languished in labs for nearly a decade
because Ebola wasn't enough of a threat to attract Big Pharma.
A clinical trial in
humans of a
vaccine based on Ab antibodies was halted in 2002
because 5 percent of the patients developed encephalitis.
Human challenge trials like this one are an extremely efficient way for scientists to tell whether a particular
vaccine is effective, but they are rarely conducted
because of the ethical dilemma of the risk it places on volunteers who are purposely exposed to a virus.
But
because these
human strains frequently mutate to adapt to their new environment in eggs, the resulting
vaccine is often an imperfect match to the actual virus that it is supposed to protect against.
The trials would be for proof of concept, to show whether researchers can, for the first time in
humans, stimulate the right B cells to start the process of making broadly neutralizing antibodies, long considered the «holy grail» of HIV
vaccine research
because they defend against infection by a broad spectrum of HIV strains.
It's lucky that
humans, and some other primates, have this particular immune reaction,
because other mammals don't, so this
vaccine wouldn't work on them.
Because of the potential risk to people, an unvaccinated exposed cat that has bitten or scratched a human should not normally be given either antiserum or vaccine, because it may mask signs of inf
Because of the potential risk to people, an unvaccinated exposed cat that has bitten or scratched a
human should not normally be given either antiserum or
vaccine,
because it may mask signs of inf
because it may mask signs of infection.
In the early days, it was the imported Siberian sled - dogs, sometimes referred to as Siberian rats
because of their lighter body structure and smaller size than the Malamutes and mixed breeds traditionally used in Alaska, that soon won fame and success - not only as very fast competitors in the grand sled - dog races of the gold - rush era, but also as couriers of mail, and even of
vaccines which saved
human lives (one very famous instance of which, is remembered through the classic Iditarod race).
This
vaccine is required by law
because rabies is 100 percent fatal and is a risk to pets and
humans.
Because of the effectiveness of some of these
vaccines, we have seen many formerly deadly diseases and viruses all but eliminated from our memories, both
human and canine.
We do however recommend the Leptospirosis
vaccine every year
because it can be contagious to
humans causing kidney failure.
Because of the serious health risks to both pets and
humans, the rabies
vaccine is required by law in most areas of the country, including Virginia.
If you've ever wondered why there's no Lyme
vaccine for
humans... that's
because it proved so dangerous in testing that it was withdrawn.
According to the Merck Veterinary Manual,
because the canine distemper virus resembles the virus responsible for
human measles, the
vaccine for the measles virus provides immunity to the canine distemper virus when there's a high level of distemper antibodies in the mother.
The rabies
vaccine is important
because this increasing threat can lead to
human exposure if not controlled.
Because there has been next to nothing published on the relationship of veterinary
vaccines to autoimmune / autoinflammatory disease, I rely on the experiences of laboratory animals like mice (ref) and the experiences of
humans.