And yet our understanding of the process of cancer immunoediting is incomplete, largely
because most tumors that come under study are already highly edited, having arisen in hosts with competent immune systems.
Although BRAF inhibitors rapidly and effectively shrink tumors, their success is limited
because most tumors become resistant to the drugs within a few months.
Not exact matches
Glioblastoma multiforme is the
most common and deadliest of the glial
tumors because the cells reproduce so rapidly.
For instance,
most common adult solid
tumors that are not cured by surgical removal are resistant to chemotherapy or radiation control, yet drug therapy is frequently offered as a «possibly effective» treatment
because both patient and physician want to believe it so.
Besides the fact that this was a celebration of my dad, my hero and one of the
most amazingly humble men on the planet, it was also a profound event
because little did we know that in just 4 short months, Daddy would be undergoing emergency surgery on a cancerous
tumor in his colon.
DIPGs are known as one of the
most challenging
tumors to treat
because cancer cells are intimately intermingled with normal brain cells in a part of the brain that can not be surgically resected.
Finding new treatments is critical
because less than 5 percent of patients with pancreatic neuroendocrine
tumors respond to everolimus, the
most commonly used pharmaceutical, François said.
The findings also have potential uses for
most other types of solid
tumors, including those affecting the lungs and ovaries,
because the same protein and enzyme are involved, François said.
Because cancer that comes back and spreads after initial treatment is often deadlier than the original
tumors, researchers thought
most of the mutations in recurrent
tumors happened after they spread.
«About five percent of people have some kind of cartilage
tumor in their bones, and in
most cases it's
because the growth - plate cartilage cells weren't fully replaced by bone tissue,» Alman said.
Scientists knew Apc was involved in stifling
tumor formation
because most colon cancers find a way to turn the gene off.
Unfortunately, in
most patients the melanoma recurs within a year
because the
tumor cells develop drug resistance.
«Studies have time and time again shown that brachytherapy is the
most important part of cervical cancer treatment,
because it is essential to eradicating the
tumor,» said Timothy Showalter, MD, a radiation oncologist at UVA Cancer Center.
Glioblastomas are particularly difficult to treat
because these
tumors grow exceptionally quickly and do not respond well to
most available chemotherapy drugs.
Because the highest grade
tumors cause the
most disruption of the BBB, the rate of movement of the contrast agent through the barrier is a strong indication that a
tumor is high grade.
Because a
tumor's RNA shows the real time changes a treatment is causing, the authors think this could be a useful tool to aid diagnosis and predict which treatment will
most benefit individual cancer patients.
«However, therapies targeting these alterations have not improved clinical outcomes,
most likely
because they have systematically failed to eradicate the proteins to which the
tumor is «addicted,»» said Dr. Iavarone.
One of the
most difficult things for a brain surgeon is figuring out exactly where a brain
tumor starts and stops
because brain
tumor tissue can be hard to distinguish from the rest of the brain.
«Therefore, any potential promising results get diluted
because novel therapies are not administered to those select patients who are
most likely to respond, based on their
tumors» molecular profile.
Because our team of pediatric specialists treats so many children with complex solid
tumors, we are particularly well versed in the treatment of these conditions and have special expertise in even the
most rare
tumors.
We believe DCs are the
most important immune cells to target
because they initiate the specific immune response that generates CTLs to kill the
tumor.
Parabens used to be the
most common preservative
because they're so effective and inexpensive, but in recent years they've been shown to mimic estrogen, causing breast cancer
tumors and increasing prevalence of early puberty in girls.
The
most well - known is a 2012 study originally published in Food and Chemical Toxicology that suggested that rats fed GMO corn were more likely to develop
tumors, but it was later retracted
because that breed of rat is prone to
tumors.
They are associated with arterial plaque, neoplasia,
tumors and a long list of metabolic imbalances.20 - 22 Homocysteine levels are higher in
most vegetarians
because of inadequate dietary protein and B vitamins (especially B12) in general or excess soy in particular.23 - 26 Soy is marketed as a «perfect protein»
because it contains all the essential amino acids, but «contains all» is not the same as contains optimum — and usable — levels and ratios.
It is believed that this is
because most dairy in the United States is full of oestrogen — a hormone that is known to generate the growth of
tumors.
Surgery alone will not make much difference
because these are highly malignant
tumors and
most have spread by the time they have been diagnosed.
Because hemangiosarcoma
tumors most often in develop in internal organs, frequently, there are few or no obvious symptoms before the onset of severe clinical signs of disease.
Because of this it can form almost anywhere but
tumors most frequently initiate in the spleen, heart, and occasionally the skin.
In cats, early removal of abdominal lumps is important
because most mammary
tumors are malignant and early excision is important in survival time.
Because of the time you spend grooming and petting your dog, you are the one
most likely to discover a
tumor of the skin.
This probably occurs
because most cases of Cushing's disease are caused by pituitary gland
tumors in the brain.
Because most bone
tumors are removed by amputating the entire limb, chemotherapy is not usually used to reduce the size of the
tumor.
Unfortunately,
most adrenal medulla
tumors are large by the time they are diagnosed
because few of them produce hormones and so there are no early clinical signs.