They suggest most women in their 40s should not have routine mammograms because the tests may cause more harm than good
because of false positive results (follow - up testing proves negative for cancer).
Not exact matches
Because only about 16 in every 100,000 people end their own lives, a test with such a level
of accuracy will give many
false positive and
false negative
results if used on the general population.
Because ovarian cancer is relatively rare, occurring in approximately one out
of every 2,500 women, a test with only 99 percent specificity would
result in
false -
positive diagnoses for 25 women, leading to unnecessary and risky surgeries and procedures.
Vexing to doctors, the great majority
of positive results are
false, not
because the tandem mass spec or the other assays have made errors but
because certain babies are «borderline normal.»
It is clear, however, that evidence
of an excess
of amino acid substitutions (at least from site - by - site tests) is no longer a sufficiently convincing demonstration
of selection, not only
because a high ratio could
result from selection on synonymous mutations rather than
positive selection on proteins [5], but also
because there is potentially a high
false discovery rate
of selected sites [6].
The cost
of testing (and often re-testing
because of false positive test
results) could possibly hinder the success
of a spay and neuter program.
Because the magnitude
of the counter acting effects depends on the degree
of non-linearity, the rms
of the residuals to a linear fit, the length
of the trend and the temporal auto - correlation
of the «weather noise», it is difficult to generalize whether the method will generally
result in too many
false positives or negatives.
3 studies that assessed screening showed limited ability to predict future maltreatment
because of high
false positive results.