The polarised blastomere will later envelop its unpolarised sister cell, which will
become embryonic tissue.
Not exact matches
The immediate payoff was a commercialization deal in age - related macular degeneration in which Pfizer
became the first big pharma company to make a move into the use of
embryonic stem cells as the basis for a
tissue regeneration therapy.
The results help fill in the scientific puzzle kicked off by Dolly's cloning, which proved that mammalian egg cells were capable of dissolving the genetic roadblocks that limit the potential of most adult cells to give rise to only a single type of
tissue — that of the organ from which they hail — whereas
embryonic stem cells have the potential to
become virtually any kind of body
tissue.
«
Embryonic stem cells are pluripotent, meaning they have the ability to
become any type of
tissue,» Fuchs says.
They propose that normal
tissue becomes primed for cancer when oncogenes are activated and tumor suppressor genes are silenced or lost, but that cancer develops only when a cell in the
tissue reverts to a more primitive,
embryonic state and starts dividing.
And so they have long sought haploid
embryonic stem cells, which can
become any kind of
tissue but contain just one set of genes, like a sperm or egg.
In 1983, Beddington set up her own lab at Oxford and
became one of the first scientists to demonstrate that
embryonic stem cells can give rise to any
tissue found in a developed body.
The research used skin samples from five men to create what are known as induced pluripotent stem cells, which closely resemble
embryonic stem cells in their ability to
become nearly any
tissue in the body.
For example, there is no equivalent of indefinitely self - renewing
embryonic stem cells in the human embryo — these are instead transient cells that very quickly specialise to
become the precursors of
tissues in the embryo.
Tumors were suspected to be
tissues that had been triggered to
become embryonic - like again, and it is now generally accepted that tumors are indeed more «
embryonic» than the
tissues they are derived from, due to the re-expression of
embryonic - related genes.
They are present during the early stages of
embryonic development and possess the ability to
become, or «differentiate,» into almost any
tissue within the body.
Neural stem cells are found in adult or fetal brain and spinal cord or derived from
embryonic stem cells, which have the capacity to
become any cell type in the body, or induced pluripotent stem (iPS) cells,
tissue - specific cells that are reprogrammed in the lab to behave like
embryonic stem cells.